6CYF
PcrV fragment with bound Fab
Summary for 6CYF
Entry DOI | 10.2210/pdb6cyf/pdb |
Descriptor | Type III secretion system protein, IgG1 antibody, kappa light chain, IgG1 antibody, heavy chain fragment, ... (4 entities in total) |
Functional Keywords | part of type 3 secretion system in pseudomonas aeruginosa, immune system |
Biological source | Pseudomonas aeruginosa More |
Total number of polymer chains | 12 |
Total formula weight | 246318.54 |
Authors | Oganesyan, V. (deposition date: 2018-04-05, release date: 2018-08-01, Last modification date: 2023-10-04) |
Primary citation | Tabor, D.E.,Oganesyan, V.,Keller, A.E.,Yu, L.,McLaughlin, R.E.,Song, E.,Warrener, P.,Rosenthal, K.,Esser, M.,Qi, Y.,Ruzin, A.,Stover, C.K.,DiGiandomenico, A. Pseudomonas aeruginosa PcrV and Psl, the Molecular Targets of Bispecific Antibody MEDI3902, Are Conserved Among Diverse Global Clinical Isolates. J. Infect. Dis., 218:1983-1994, 2018 Cited by PubMed: 30016475DOI: 10.1093/infdis/jiy438 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.78 Å) |
Structure validation
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