4N0F
Human FcRn complexed with human serum albumin
Summary for 4N0F
Entry DOI | 10.2210/pdb4n0f/pdb |
Related | 1AO6 1EXU 4N0U |
Descriptor | IgG receptor FcRn large subunit p51, Beta-2-microglobulin, Serum albumin (3 entities in total) |
Functional Keywords | alpha/beta, receptor, igg constant domain, membrane, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Single-pass type I membrane protein (By similarity): P55899 Secreted: P61769 P02768 |
Total number of polymer chains | 12 |
Total formula weight | 433760.87 |
Authors | Oganesyan, V.,Wu, H.,Dall'Acqua, W.F. (deposition date: 2013-10-01, release date: 2014-02-05, Last modification date: 2014-04-09) |
Primary citation | Oganesyan, V.,Damschroder, M.M.,Cook, K.E.,Li, Q.,Gao, C.,Wu, H.,Dall'acqua, W.F. Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms. J.Biol.Chem., 289:7812-7824, 2014 Cited by PubMed: 24469444DOI: 10.1074/jbc.M113.537563 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.02 Å) |
Structure validation
Download full validation report