6IRX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6irx by Molmil](/molmil-images/mine/6irx) | |
6IRY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6iry by Molmil](/molmil-images/mine/6iry) | Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH | 分子名称: | 1,2-ETHANEDIOL, PDX1 C-terminal-inhibiting factor 1, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2018-11-14 | 公開日 | 2018-12-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase. Science, 363, 2019
|
|
5B2T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5b2t by Molmil](/molmil-images/mine/5b2t) | Crystal structure of the Streptococcus pyogenes Cas9 VRER variant in complex with sgRNA and target DNA (TGCG PAM) | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CRISPR-associated endonuclease Cas9, ... | 著者 | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2016-02-02 | 公開日 | 2016-03-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9 Mol.Cell, 61, 2016
|
|
5B2S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5b2s by Molmil](/molmil-images/mine/5b2s) | Crystal structure of the Streptococcus pyogenes Cas9 EQR variant in complex with sgRNA and target DNA (TGAG PAM) | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CRISPR-associated endonuclease Cas9, ... | 著者 | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2016-02-02 | 公開日 | 2016-03-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9 Mol.Cell, 61, 2016
|
|
7WAH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wah by Molmil](/molmil-images/mine/7wah) | Structure of Cas7-11 in complex with guide RNA and target RNA | 分子名称: | CRISPR-associated RAMP family protein, ZINC ION, crRNA (39-MER), ... | 著者 | Kato, K, Okazaki, S, Isayama, Y, Nishizawa, T, Nishimasu, H. | 登録日 | 2021-12-14 | 公開日 | 2022-06-15 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.45 Å) | 主引用文献 | Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex. Cell, 185, 2022
|
|
5B2R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5b2r by Molmil](/molmil-images/mine/5b2r) | Crystal structure of the Streptococcus pyogenes Cas9 VQR variant in complex with sgRNA and target DNA (TGA PAM) | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CRISPR-associated endonuclease Cas9, ... | 著者 | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2016-02-02 | 公開日 | 2016-03-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9 Mol.Cell, 61, 2016
|
|
6IRZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6irz by Molmil](/molmil-images/mine/6irz) | Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH and m7G-capped RNA | 分子名称: | 1,2-ETHANEDIOL, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, PDX1 C-terminal-inhibiting factor 1, ... | 著者 | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2018-11-15 | 公開日 | 2018-12-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase. Science, 363, 2019
|
|
7V94
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v94 by Molmil](/molmil-images/mine/7v94) | Cryo-EM structure of the Cas12c2-sgRNA-target DNA ternary complex | 分子名称: | Cas12c2, sgRNA, target DNA (non target strand), ... | 著者 | Kurihara, N, Hirano, H, Tomita, A, Kobayashi, K, Kusakizako, T, Nishizawa, T, Yamashita, K, Nishimasu, H, Nureki, O. | 登録日 | 2021-08-24 | 公開日 | 2022-04-13 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structure of the type V-C CRISPR-Cas effector enzyme. Mol.Cell, 82, 2022
|
|
7V93
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v93 by Molmil](/molmil-images/mine/7v93) | Cryo-EM structure of the Cas12c2-sgRNA binary complex | 分子名称: | cas12c2, sgRNA | 著者 | Kurihara, N, Hirano, H, Tomita, A, Kobayashi, K, Kusakizako, T, Nishizawa, T, Yamashita, K, Nishimasu, H, Nureki, O. | 登録日 | 2021-08-24 | 公開日 | 2022-04-13 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of the type V-C CRISPR-Cas effector enzyme. Mol.Cell, 82, 2022
|
|
7Y9X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y9x by Molmil](/molmil-images/mine/7y9x) | Structure of the Cas7-11-Csx29-guide RNA complex | 分子名称: | CHAT domain-containing protein, CRISPR-associated RAMP family protein, ZINC ION, ... | 著者 | Kato, K, Okazaki, S, Ishikawa, J, Isayama, Y, Nishizawa, T, Nishimasu, H. | 登録日 | 2022-06-26 | 公開日 | 2022-11-09 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.49 Å) | 主引用文献 | RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease. Science, 378, 2022
|
|
3A27
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3a27 by Molmil](/molmil-images/mine/3a27) | Crystal structure of M. jannaschii TYW2 in complex with AdoMet | 分子名称: | S-ADENOSYLMETHIONINE, Uncharacterized protein MJ1557 | 著者 | Umitsu, M, Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2009-04-28 | 公開日 | 2009-09-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.005 Å) | 主引用文献 | Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2 Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
7V6B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v6b by Molmil](/molmil-images/mine/7v6b) | Structure of the Dicer-2-R2D2 heterodimer | 分子名称: | Dicer-2, isoform A, R2D2 | 著者 | Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O. | 登録日 | 2021-08-20 | 公開日 | 2022-03-23 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex. Nature, 607, 2022
|
|
7V6C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v6c by Molmil](/molmil-images/mine/7v6c) | Structure of the Dicer-2-R2D2 heterodimer bound to small RNA duplex | 分子名称: | Dicer-2, isoform A, R2D2, ... | 著者 | Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O. | 登録日 | 2021-08-20 | 公開日 | 2022-03-23 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex. Nature, 607, 2022
|
|