6IRZ

Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH and m7G-capped RNA

Summary for 6IRZ

Entry DOI	10.2210/pdb6irz/pdb
Descriptor	PDX1 C-terminal-inhibiting factor 1, S-ADENOSYL-L-HOMOCYSTEINE, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	rna methylation, methyltransferase, m6a, n6-methyladenosine, transferase
Biological source	Danio rerio (Zebrafish)
Total number of polymer chains	1
Total formula weight	58600.64
Authors	Hirano, S.,Nishimasu, H.,Ishitani, R.,Nureki, O. (deposition date: 2018-11-15, release date: 2018-12-05, Last modification date: 2023-11-22)
Primary citation	Akichika, S.,Hirano, S.,Shichino, Y.,Suzuki, T.,Nishimasu, H.,Ishitani, R.,Sugita, A.,Hirose, Y.,Iwasaki, S.,Nureki, O.,Suzuki, T. Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase. Science, 363:-, 2019 Cited by PubMed: 30467178 DOI: 10.1126/science.aav0080 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation