6IRZ
Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH and m7G-capped RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PDX1 C-terminal-inhibiting factor 1 | polymer | 496 | 57570.8 | 1 | UniProt (A0A0R4IKJ1) Pfam (PF12237) | Danio rerio (Zebrafish) | |
| 2 | B (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 3 | C, D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | F (A) | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE | non-polymer | 459.2 | 1 | Chemie (M7G) | |||
| 5 | G (A) | water | water | 18.0 | 160 | Chemie (HOH) |
Sequence modifications
A: 178 - 673 (UniProt: A0A0R4IKJ1)
| PDB | External Database | Details |
|---|---|---|
| Val 308 | Ala 308 | engineered mutation |
| Asn 344 | His 344 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 57570.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1029.9 | |
| All* | Total formula weight | 58600.6 |
