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PDB: 12 results

8P34
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Tau filaments extracted from human brain with the DeltaK281 mutation in MAPT
Descriptor: Microtubule-associated protein tau
Authors:Schweighauser, M, Garringer, H.J, Klingstedt, T, Masuda-Suzukake, M, Murrell, J.R, Vidal, R, Scheres, S.H.W, Goedert, M, Ghetti, B, Newell, K.L.
Deposit date:2023-05-17
Release date:2023-07-05
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Mutation ∆K281 in MAPT causes Pick's disease.
Acta Neuropathol, 146, 2023
7Q4M
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Type II beta-amyloid 42 Filaments from Human Brain
Descriptor: Amyloid-beta precursor protein, UNKNOWN ATOM OR ION
Authors:Yang, Y, Arseni, D, Zhang, W, Huang, M, Lovestam, S.K.A, Schweighauser, M, Kotecha, A, Murzin, A.G, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Garringer, H.J, Gelpi, E, Newell, K.L, Kovacs, G.G, Vidal, R, Ghetti, B, Falcon, B, Scheres, S.H.W, Goedert, M.
Deposit date:2021-11-01
Release date:2021-11-24
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structures of amyloid-beta 42 filaments from human brains.
Science, 375, 2022
7Q4B
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Type I beta-amyloid 42 Filaments from Human Brain
Descriptor: Amyloid-beta precursor protein, UNKNOWN ATOM OR ION
Authors:Yang, Y, Arseni, D, Zhang, W, Huang, M, Lovestam, S.K.A, Schweighauser, M, Kotecha, A, Murzin, A.G, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Garringer, H.J, Gelpi, E, Newell, K.L, Kovacs, G.G, Vidal, R, Ghetti, B, Falcon, B, Scheres, S.H.W, Goedert, M.
Deposit date:2021-10-30
Release date:2021-11-24
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Cryo-EM structures of amyloid-beta 42 filaments from human brains.
Science, 375, 2022
6NWP
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Chronic traumatic encephalopathy Type I Tau filament
Descriptor: Microtubule-associated protein tau
Authors:Falcon, B, Zivanov, J, Zhang, W, Murzin, A.G, Garringer, H.J, Vidal, R, Crowther, R.A, Newell, K.L, Ghetti, B, Goedert, M, Scheres, H.W.
Deposit date:2019-02-07
Release date:2019-03-27
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules.
Nature, 568, 2019
6NWQ
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Chronic traumatic encephalopathy Type II Tau filament
Descriptor: Microtubule-associated protein tau
Authors:Falcon, B, Zivanov, J, Zhang, W, Murzin, A.G, Garringer, H.J, Vidal, R, Crowther, R.A, Newell, K.L, Ghetti, B, Goedert, M, Scheres, H.W.
Deposit date:2019-02-07
Release date:2019-03-27
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules.
Nature, 568, 2019
7NRV
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Paired helical filament from Alzheimer's disease with PET ligand APN-1607
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
Deposit date:2021-03-04
Release date:2021-03-24
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRQ
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Paired helical filament from primary age-related tauopathy brain
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
Deposit date:2021-03-04
Release date:2021-03-24
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRT
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Conformation 2 of straight filament from primary age-related tauopathy brain
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
Deposit date:2021-03-04
Release date:2021-03-24
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRX
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BU of 7nrx by Molmil
Straight filament from Alzheimer's disease with PET ligand APN-1607
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
Deposit date:2021-03-04
Release date:2021-03-24
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRS
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BU of 7nrs by Molmil
Conformation 1 of straight filament from primary age-related tauopathy brain
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
Deposit date:2021-03-04
Release date:2021-03-24
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
8QN7
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BU of 8qn7 by Molmil
Amyloid-beta 40 type 1 filament from the leptomeninges of individual with Alzheimer's disease and cerebral amyloid angiopathy
Descriptor: Amyloid-beta A4 protein
Authors:Yang, Y, Murzin, A.S, Peak-Chew, S.Y, Franco, C, Newell, K.L, Ghetti, B, Goedert, M, Scheres, S.H.W.
Deposit date:2023-09-25
Release date:2023-12-13
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM structures of A beta 40 filaments from the leptomeninges of individuals with Alzheimer's disease and cerebral amyloid angiopathy.
Acta Neuropathol Commun, 11, 2023
8QN6
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Amyloid-beta 40 type 2 filament from the leptomeninges of individual with Alzheimer's disease and cerebral amyloid angiopathy
Descriptor: Amyloid-beta A4 protein
Authors:Yang, Y, Murzin, A.S, Peak-Chew, S.Y, Franco, C, Newell, K.L, Ghetti, B, Goedert, M, Scheres, S.H.W.
Deposit date:2023-09-25
Release date:2023-12-13
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Cryo-EM structures of A beta 40 filaments from the leptomeninges of individuals with Alzheimer's disease and cerebral amyloid angiopathy.
Acta Neuropathol Commun, 11, 2023

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PDB entries from 2024-06-12

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