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PDB: 35 件
1VIF
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STRUCTURE OF DIHYDROFOLATE REDUCTASE
分子名称: DIHYDROFOLATE REDUCTASE, FOLIC ACID
著者Narayana, N, Matthews, D.A, Howell, E.E, Xuong, N.-H.
登録日1996-10-03
公開日1997-10-22
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A plasmid-encoded dihydrofolate reductase from trimethoprim-resistant bacteria has a novel D2-symmetric active site.
Nat.Struct.Biol., 2, 1995
1VIE
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STRUCTURE OF DIHYDROFOLATE REDUCTASE
分子名称: DIHYDROFOLATE REDUCTASE
著者Narayana, N, Matthews, D.A, Howell, E.E, Xuong, N.-H.
登録日1996-10-03
公開日1997-10-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A plasmid-encoded dihydrofolate reductase from trimethoprim-resistant bacteria has a novel D2-symmetric active site.
Nat.Struct.Biol., 2, 1995
2GQV
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High-resolution structure of a plasmid-encoded dihydrofolate reductase: pentagonal network of water molecules in the D2-symmetric active site
分子名称: Dihydrofolate reductase type 2
著者Narayana, N.
登録日2006-04-22
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献High-resolution structure of a plasmid-encoded dihydrofolate reductase: pentagonal network of water molecules in the D(2)-symmetric active site.
Acta Crystallogr.,Sect.D, 62, 2006
1JB6
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Crystal Structure of Dimerization Domain (1-33) of HNF-1alpha
分子名称: HEPATOCYTE NUCLEAR FACTOR 1-ALPHA
著者Narayana, N, Hua, Q.-X, Weiss, M.A.
登録日2001-06-01
公開日2001-07-11
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The dimerization domain of HNF-1alpha: structure and plasticity of an intertwined four-helix bundle with application to diabetes mellitus.
J.Mol.Biol., 310, 2001
2GYP
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Diabetes mellitus due to a frustrated Schellman motif in HNF-1a
分子名称: Hepatocyte nuclear factor 1-alpha
著者Narayana, N, Phillips, N.B, Hua, Q.X, Jia, W, Weiss, M.A.
登録日2006-05-09
公開日2007-03-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Diabetes mellitus due to misfolding of a beta-cell transcription factor: stereospecific frustration of a Schellman motif in HNF-1alpha.
J.Mol.Biol., 362, 2006
2F8W
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Crystal structure of d(CACGTG)2
分子名称: 1,3-DIAMINOPROPANE, 5'-D(*CP*AP*CP*GP*TP*G)-3', SPERMINE
著者Narayana, N, Shamala, N, Ganesh, K.N, Viswamitra, M.A.
登録日2005-12-04
公開日2006-01-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Interaction between the Z-Type DNA Duplex and 1,3-Propanediamine: Crystal Structure of d(CACGTG)2 at 1.2 A Resolution
Biochemistry, 45, 2006
1BX6
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CRYSTAL STRUCTURE OF THE POTENT NATURAL PRODUCT INHIBITOR BALANOL IN COMPLEX WITH THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE
分子名称: BALANOL, CAMP-DEPENDENT PROTEIN KINASE
著者Narayana, N, Xuong, N.-H, Ten Eyck, L.F, Taylor, S.S.
登録日1998-10-13
公開日1999-04-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of cAMP-dependent protein kinase.
Biochemistry, 38, 1999
1FMO
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CRYSTAL STRUCTURE OF A POLYHISTIDINE-TAGGED RECOMBINANT CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE COMPLEXED WITH THE PEPTIDE INHIBITOR PKI(5-24) AND ADENOSINE
分子名称: ADENOSINE, CAMP-DEPENDENT PROTEIN KINASE, HEAT STABLE RABBIT SKELETAL MUSCLE INHIBITOR PROTEIN
著者Narayana, N, Cox, S, Shaltiel, S, Taylor, S.S, Xuong, N.-H.
登録日1997-07-08
公開日1998-01-14
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of cAMP-dependent protein kinase complexed with the peptide inhibitor PKI(5-24) and adenosine.
Biochemistry, 36, 1997
1BKX
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A BINARY COMPLEX OF THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE AND ADENOSINE FURTHER DEFINES CONFORMATIONAL FLEXIBILITY
分子名称: ADENOSINE-5'-MONOPHOSPHATE, CAMP-DEPENDENT PROTEIN KINASE
著者Narayana, N, Cox, S, Xuong, N, Ten Eyck, L.F, Taylor, S.S.
登録日1997-07-01
公開日1998-03-18
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A binary complex of the catalytic subunit of cAMP-dependent protein kinase and adenosine further defines conformational flexibility.
Structure, 5, 1997
3BSE
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Crystal structure analysis of a 16-base-pair B-DNA
分子名称: CALCIUM ION, DNA (5'-D(*DA*DCP*DAP*DCP*DTP*DAP*DCP*DAP*DAP*DTP*DGP*DTP*DTP*DGP*DCP*DAP*DAP*DT)-3'), DNA (5'-D(*DG*DTP*DAP*DTP*DTP*DGP*DCP*DAP*DAP*DCP*DAP*DTP*DTP*DGP*DTP*DAP*DGP*DT)-3')
著者Narayana, N.
登録日2007-12-23
公開日2008-12-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystallographic Analysis of a Sex-Specific Enhancer Element: Sequence-Dependent DNA Structure, Hydration, and Dynamics
J.Mol.Biol., 385, 2009
1D28
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CRYSTAL AND MOLECULAR STRUCTURE OF A DNA FRAGMENT: D(CGTGAATTCACG)
分子名称: DNA (5'-D(*CP*GP*TP*GP*AP*AP*TP*TP*CP*AP*CP*G)-3')
著者Narayana, N, Ginell, S.L, Russu, I.M, Berman, H.M.
登録日1990-12-18
公開日1992-04-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal and molecular structure of a DNA fragment: d(CGTGAATTCACG).
Biochemistry, 30, 1991
7WVL
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Structure of P4A2 Fab in complex with Spike-RBD from SARS-CoV-2
分子名称: P4A2 Fab Light Chain, P4A2 Fab heavy chain, Spike protein S1
著者Narayanan, N, Nair, D.T.
登録日2022-02-10
公開日2022-12-07
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A broadly neutralizing monoclonal antibody overcomes the mutational landscape of emerging SARS-CoV-2 variants of concern.
Plos Pathog., 18, 2022
6K0W
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DNA methyltransferase in complex with sinefungin
分子名称: Adenine specific DNA methyltransferase (Mod), SINEFUNGIN
著者Narayanan, N, Nair, D.T.
登録日2019-05-07
公開日2019-12-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Tetramerization at Low pH Licenses DNA Methylation Activity of M.HpyAXI in the Presence of Acid Stress.
J.Mol.Biol., 432, 2020
2KZ9
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Structure of E1-69 of Yeast V-ATPase
分子名称: V-type proton ATPase subunit E
著者Sankaranarayanan, N, Gruber, G.
登録日2010-06-14
公開日2011-02-16
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献NMR Solution Structure of Subunit E (E1-69) of the Saccharomyces cerevisiae V1VO ATPase
To be Published
2K88
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Association of subunit d (Vma6p) and E (Vma4p) with G (Vma10p) and the NMR solution structure of subunit G (G1-59) of the Saccharomyces cerevisiae V1VO ATPase
分子名称: Vacuolar proton pump subunit G
著者Sankaranarayanan, N, Gayen, S, Thaker, Y, Subramanian, V, Manimekalai, M.S.S, Gruber, G.
登録日2008-09-04
公開日2009-08-11
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Assembly of subunit d (Vma6p) and G (Vma10p) and the NMR solution structure of subunit G (G(1-59)) of the Saccharomyces cerevisiae V(1)V(O) ATPase.
Biochim.Biophys.Acta, 1787, 2009
2P4T
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Structure of the Q67H mutant of R67 dihydrofolate reductase-NADP+ complex reveals a novel cofactor binding mode
分子名称: Dihydrofolate reductase type 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Divya, N, Grifith, E, Narayana, N.
登録日2007-03-13
公開日2007-06-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structure of the Q67H mutant of R67 dihydrofolate reductase-NADP+ complex reveals a novel cofactor binding mode.
Protein Sci., 16, 2007
3GZO
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HUMAN SOD1 G93A Variant
分子名称: COPPER (II) ION, GLYCEROL, MALONATE ION, ...
著者Galaleldeen, A, Taylor, A.B, Narayana, N, Whitson, L.J, Hart, P.J.
登録日2009-04-07
公開日2009-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A.
Arch.Biochem.Biophys., 492, 2009
2WKO
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Structure of metal loaded Pathogenic SOD1 Mutant G93A.
分子名称: COPPER (II) ION, IODIDE ION, SUPEROXIDE DISMUTASE [CU-ZN], ...
著者Antonyuk, S.V, Galaleldeen, A, Strange, R, Whitson, L, Narayana, N, Taylor, A, Schuermann, J.P, Holloway, S.P, Hasnain, S.S, Hart, P.J.
登録日2009-06-16
公開日2009-11-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural and Biophysical Properties of Metal-Free Pathogenic Sod1 Mutants A4V and G93A.
Arch.Biochem.Biophys., 492, 2009
1KLS
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NMR Structure of the ZFY-6T[Y10L] Zinc Finger
分子名称: ZINC FINGER Y-CHROMOSOMAL PROTEIN, ZINC ION
著者Lachenmann, M.J, Ladbury, J.E, Phillips, N.B, Narayana, N, Qian, X, Weiss, M.A.
登録日2001-12-12
公開日2002-03-13
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献The hidden thermodynamics of a zinc finger.
J.Mol.Biol., 316, 2002
1KLR
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NMR Structure of the ZFY-6T[Y10F] Zinc Finger
分子名称: ZINC FINGER Y-CHROMOSOMAL PROTEIN, ZINC ION
著者Lachenmann, M.J, Ladbury, J.E, Phillips, N.B, Narayana, N, Qian, X, Weiss, M.A.
登録日2001-12-12
公開日2002-03-13
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献The hidden thermodynamics of a zinc finger.
J.Mol.Biol., 316, 2002
1TPU
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S96P CHANGE IS A SECOND-SITE SUPPRESSOR FOR H95N SLUGGISH MUTANT TRIOSEPHOSPHATE ISOMERASE
分子名称: PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Stock, A.M, Narayana, N, Xuong, Ng.H, Knowles, J.R, Petsko, G.A, Ringe, D.
登録日1994-11-07
公開日1995-04-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis for pseudoreversion of the H95N lesion by the secondary S96P mutation in triosephosphate isomerase.
Biochemistry, 35, 1996
1TPV
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S96P CHANGE IS A SECOND-SITE SUPPRESSOR FOR H95N SLUGGISH MUTANT TRIOSEPHOSPHATE ISOMERASE
分子名称: PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Stock, A.M, Narayana, N, Xuong, Ng.H, Knowles, J.R, Petsko, G.A, Ringe, D.
登録日1994-11-07
公開日1995-04-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis for pseudoreversion of the H95N lesion by the secondary S96P mutation in triosephosphate isomerase.
Biochemistry, 35, 1996
1TPW
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TRIOSEPHOSPHATE ISOMERASE DRINKS WATER TO KEEP HEALTHY
分子名称: PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Stock, A.M, Narayana, N, Xuong, Ng.H, Knowles, J.R, Petsko, G.A, Ringe, D.
登録日1994-11-07
公開日1995-04-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The role of water in the catalytic efficiency of triosephosphate isomerase.
Biochemistry, 38, 1999
8U7Z
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KCTD5/Cullin3/Gbeta1gamma2 Complex: Local Refinment of KCTD5(CTD)/Gbeta1gamma2
分子名称: BTB/POZ domain-containing protein KCTD5, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
著者Kuntz, D.A, Nguyen, D.M, Narayanan, N, Prive, G.G.
登録日2023-09-15
公開日2023-10-11
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structure and dynamics of a pentameric KCTD5/CUL3/G beta gamma E3 ubiquitin ligase complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8U81
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KCTD5/Cullin3/Gbeta1gamma2 Complex: State A From Composite RELION Multi-body Refinement Map
分子名称: BTB/POZ domain-containing protein KCTD5, Cullin-3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Kuntz, D.A, Nguyen, D.M, Narayanan, N, Prive, G.G.
登録日2023-09-15
公開日2023-10-11
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.82 Å)
主引用文献Structure and dynamics of a pentameric KCTD5/CUL3/G beta gamma E3 ubiquitin ligase complex.
Proc.Natl.Acad.Sci.USA, 121, 2024

 

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