7WVL

Structure of P4A2 Fab in complex with Spike-RBD from SARS-CoV-2

Summary for 7WVL

• Entry DOI: 10.2210/pdb7wvl/pdb
• Descriptor: P4A2 Fab Light Chain, P4A2 Fab heavy chain, Spike protein S1, ... (4 entities in total)
• Functional Keywords: fab, spike-rbd, complex, antiviral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 3
• Total formula weight: 71534.84

Authors

Narayanan, N.,Nair, D.T. (deposition date: 2022-02-10, release date: 2022-12-07, Last modification date: 2022-12-21)

• Primary citation: Parray, H.A.,Narayanan, N.,Garg, S.,Rizvi, Z.A.,Shrivastava, T.,Kushwaha, S.,Singh, J.,Murugavelu, P.,Anantharaj, A.,Mehdi, F.,Raj, N.,Singh, S.,Dandotiya, J.,Lukose, A.,Jamwal, D.,Kumar, S.,Chiranjivi, A.,Dhyani, S.,Mishra, N.,Kumar, S.,Jakhar, K.,Sonar, S.,Panchal, A.K.,Tripathy, M.R.,Chowdhury, S.R.,Ahmed, S.,Samal, S.,Mani, S.,Bhattacharyya, S.,Das, S.,Sinha, S.,Luthra, K.,Batra, G.,Sehgal, D.,Medigeshi, G.R.,Sharma, C.,Awasthi, A.,Garg, P.K.,Nair, D.T.,Kumar, R.; A broadly neutralizing monoclonal antibody overcomes the mutational landscape of emerging SARS-CoV-2 variants of concern.; Plos Pathog., 18:e1010994-e1010994, 2022; PubMed: 36508467; DOI: 10.1371/journal.ppat.1010994

Experimental method

X-RAY DIFFRACTION (3 Å)