2GQV
High-resolution structure of a plasmid-encoded dihydrofolate reductase: pentagonal network of water molecules in the D2-symmetric active site
Summary for 2GQV
| Entry DOI | 10.2210/pdb2gqv/pdb |
| Related | 1VIE 1VIF |
| Descriptor | Dihydrofolate reductase type 2 (2 entities in total) |
| Functional Keywords | anisotropic refinement, atomic-resolution structure, folate metabolism, plasmid-encoded r67 dhfr, tmp-resistant dhfr, oxidoreductase |
| Biological source | Escherichia coli |
| Total number of polymer chains | 1 |
| Total formula weight | 6732.53 |
| Authors | Narayana, N. (deposition date: 2006-04-22, release date: 2007-04-24, Last modification date: 2023-08-30) |
| Primary citation | Narayana, N. High-resolution structure of a plasmid-encoded dihydrofolate reductase: pentagonal network of water molecules in the D(2)-symmetric active site. Acta Crystallogr.,Sect.D, 62:695-706, 2006 Cited by PubMed: 16790925DOI: 10.1107/S0907444906014764 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.1 Å) |
Structure validation
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