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PDB: 97 件
3E5T
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Crystal Structure Analysis of FP611
分子名称: Red fluorescent protein eqFP611
著者Nar, H, Nienhaus, K, Nienhaus, U, Wiedenmann, J.
登録日2008-08-14
公開日2008-09-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Trans-cis isomerization is responsible for the red-shifted fluorescence in variants of the red fluorescent protein eqFP611.
J.Am.Chem.Soc., 130, 2008
2BTJ
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Fluorescent Protein EosFP - red form
分子名称: Green to red photoconvertible GFP-like protein EosFP
著者Nar, H, Nienhaus, K, Wiedenmann, J, Nienhaus, G.U.
登録日2005-06-01
公開日2005-06-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Photo-Induced Protein Cleavage and Green-to-Red Conversion of Fluorescent Protein Eosfp.
Proc.Natl.Acad.Sci.USA, 102, 2005
2AZU
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X-RAY CRYSTAL STRUCTURE OF THE TWO SITE-SPECIFIC MUTANTS HIS35*GLN AND HIS35*LEU OF AZURIN FROM PSEUDOMONAS AERUGINOSA
分子名称: AZURIN, COPPER (II) ION, NITRATE ION
著者Nar, H, Messerschmidt, A, Huber, R.
登録日1991-01-11
公開日1993-07-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray crystal structure of the two site-specific mutants His35Gln and His35Leu of azurin from Pseudomonas aeruginosa.
J.Mol.Biol., 218, 1991
5F2P
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Crystal structure of the BRD9 bromodomain in complex with compound 3.
分子名称: 2-(dimethylamino)-6-methyl-pyrido[4,3-d]pyrimidin-5-one, BRD9
著者Nar, H, Fiegen, D, Zoephel, A, Bader, G.
登録日2015-12-02
公開日2016-03-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor.
J.Med.Chem., 59, 2016
6TLA
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CRYSTAL STRUCTURE OF LECTIN-LIKE OX-LDL RECEPTOR 1 (C 1 2 1)
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Oxidized low-density lipoprotein receptor 1
著者Nar, H, Fiegen, D, Schnapp, G.
登録日2019-12-02
公開日2020-07-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献A small-molecule inhibitor of lectin-like oxidized LDL receptor-1 acts by stabilizing an inactive receptor tetramer state
Commun Chem, 2020
6TL7
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CRYSTAL STRUCTURE OF LECTIN-LIKE OX-LDL RECEPTOR 1 (P212121)
分子名称: NICKEL (II) ION, Oxidized low-density lipoprotein receptor 1
著者Nar, H, Fiegen, D, Schnapp, G.
登録日2019-12-02
公開日2020-07-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献A small-molecule inhibitor of lectin-like oxidized LDL receptor-1 acts by stabilizing an inactive receptor tetramer state
Commun Chem, 2020
3NJW
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First High Resolution Crystal Structure of a Lasso Peptide
分子名称: Bicyclic peptide BI-32169
著者Nar, H, Schmid, A, Puder, C, Potterat, O.
登録日2010-06-18
公開日2010-09-01
最終更新日2011-08-10
実験手法X-RAY DIFFRACTION (0.86 Å)
主引用文献High-resolution crystal structure of a lasso Peptide.
Chemmedchem, 5, 2010
1DB2
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CRYSTAL STRUCTURE OF NATIVE PLASMINOGEN ACTIVATOR INHIBITOR-1
分子名称: PLASMINOGEN ACTIVATOR INHIBITOR-1
著者Nar, H, Bauer, M, Stassen, J.M, Lang, D, Gils, A, Declerck, P.
登録日1999-11-02
公開日1999-11-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation.
J.Mol.Biol., 297, 2000
1N3R
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Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I
分子名称: GTP cyclohydrolase I, GUANOSINE-5'-TRIPHOSPHATE
著者Rebelo, J, Auerbach, G, Bader, G, Bracher, A, Nar, H, Hoesl, C, Schramek, N, Kaiser, J, Bacher, A, Huber, R, Fischer, M.
登録日2002-10-29
公開日2003-10-14
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Biosynthesis of Pteridines. Reaction Mechanism of GTP Cyclohydrolase I
J.MOL.BIOL., 326, 2003
1N3T
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Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I
分子名称: GTP cyclohydrolase I, GUANOSINE-5'-TRIPHOSPHATE
著者Rebelo, J, Auerbach, G, Bader, G, Bracher, A, Nar, H, Hoesl, C, Schramek, N, Kaiser, J, Bacher, A, Huber, R, Fischer, M.
登録日2002-10-29
公開日2003-10-14
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Biosynthesis of Pteridines. Reaction Mechanism of GTP Cyclohydrolase I
J.MOL.BIOL., 326, 2003
1N3S
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Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I
分子名称: GTP cyclohydrolase I, GUANOSINE-5'-TRIPHOSPHATE
著者Rebelo, J, Auerbach, G, Bader, G, Bracher, A, Nar, H, Hoesl, C, Schramek, N, Kaiser, J, Bacher, A, Huber, R, Fischer, M.
登録日2002-10-29
公開日2004-03-02
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Biosynthesis of Pteridines. Reaction Mechanism of GTP Cyclohydrolase I
J.MOL.BIOL., 326, 2003
8C7H
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Cryo-EM Map of the latTGF-beta 28G11 Fab complex
分子名称: 28G11 Fab heavy chain, 28G11 Fab light chain, Transforming growth factor beta activator LRRC32, ...
著者Ebenhoch, R, Nar, H.
登録日2023-01-16
公開日2023-03-01
最終更新日2023-03-29
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Anti-GARP Antibodies Inhibit Release of TGF-beta by Regulatory T Cells via Different Modes of Action, but Do Not Influence Their Function In Vitro.
Immunohorizons, 7, 2023
1FBX
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CRYSTAL STRUCTURE OF ZINC-CONTAINING E.COLI GTP CYCLOHYDROLASE I
分子名称: CHLORIDE ION, GTP CYCLOHYDROLASE I, ZINC ION
著者Auerbach, G, Herrmann, A, Bracher, A, Bader, A, Gutlich, M, Fischer, M, Neukamm, M, Nar, H, Garrido-Franco, M, Richardson, J, Huber, R, Bacher, A.
登録日2000-07-17
公開日2001-02-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Zinc plays a key role in human and bacterial GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 97, 2000
1FB1
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CRYSTAL STRUCTURE OF HUMAN GTP CYCLOHYDROLASE I
分子名称: GTP CYCLOHYDROLASE I, ISOPROPYL ALCOHOL, ZINC ION
著者Auerbach, G, Herrmann, A, Bracher, A, Bader, G, Gutlich, M, Fischer, M, Neukamm, M, Nar, H, Garrido-Franco, M, Richardson, J, Huber, R, Bacher, A.
登録日2000-07-14
公開日2000-12-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Zinc plays a key role in human and bacterial GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 97, 2000
6Z86
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human GTP cyclohydrolase I in complex with 7-deaza-GTP
分子名称: 7-deaza-GTP, GTP cyclohydrolase 1, ZINC ION
著者Ebenhoch, R, Nar, H.
登録日2020-06-02
公開日2020-12-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.206 Å)
主引用文献A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
1A9C
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GTP CYCLOHYDROLASE I (C110S MUTANT) IN COMPLEX WITH GTP
分子名称: GTP CYCLOHYDROLASE I, GUANOSINE-5'-TRIPHOSPHATE
著者Auerbach, G, Nar, H, Bracher, A, Bacher, A, Huber, R.
登録日1998-04-04
公開日1999-05-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献GTP Cyclohydrolase I in Complex with GTP at 2.1 A Resolution
To be Published
1A8R
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GTP CYCLOHYDROLASE I (H112S MUTANT) IN COMPLEX WITH GTP
分子名称: GTP CYCLOHYDROLASE I, GUANOSINE-5'-TRIPHOSPHATE
著者Auerbach, G, Nar, H, Bracher, A, Bacher, A, Huber, R.
登録日1998-03-27
公開日1999-05-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I.
J.Mol.Biol., 326, 2003
6Z80
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stimulatory human GTP cyclohydrolase I - GFRP complex
分子名称: 8-OXO-GUANOSINE-5'-TRIPHOSPHATE, GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, ...
著者Ebenhoch, R, Nar, H, Vonck, J.
登録日2020-06-02
公開日2020-12-09
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
6Z85
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inhibitory human GTP cyclohydrolase I - GFRP complex
分子名称: 7,8-DIHYDROBIOPTERIN, GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, ...
著者Ebenhoch, R, Nar, H, Vonck, J.
登録日2020-06-02
公開日2020-12-09
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
1VLX
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STRUCTURE OF ELECTRON TRANSFER (COBALT-PROTEIN)
分子名称: AZURIN, COBALT (II) ION
著者Bonander, N, Vanngard, T, Tsai, L.-C, Langer, V, Nar, H, Sjolin, L.
登録日1996-10-08
公開日1997-03-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The metal site of Pseudomonas aeruginosa azurin, revealed by a crystal structure determination of the Co(II) derivative and Co-EPR spectroscopy.
Proteins, 27, 1997
6Z88
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human GTP cyclohydrolase I in complex with allosteric inhibitor
分子名称: 5-azanyl-[1,3]thiazolo[5,4-d]pyrimidine-2,7-dione, GTP cyclohydrolase 1, ZINC ION
著者Ebenhoch, R, Nar, H.
登録日2020-06-02
公開日2020-12-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.687 Å)
主引用文献A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
1NZR
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CRYSTAL STRUCTURE OF THE AZURIN MUTANT NICKEL-TRP48MET FROM PSEUDOMONAS AERUGINOSA AT 2.2 ANGSTROMS RESOLUTION
分子名称: AZURIN, NICKEL (II) ION, NITRATE ION
著者Tsai, L.-C, Sjolin, L, Langer, V, Bonander, N, Karlsson, B.G, Vanngard, T, Hammann, C, Nar, H.
登録日1994-12-09
公開日1995-02-27
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the azurin mutant nickel-Trp48Met from Pseudomonas aeruginosa at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 51, 1995
1ILU
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X-RAY CRYSTAL STRUCTURE THE TWO SITE-SPECIFIC MUTANTS ILE7SER AND PHE110SER OF AZURIN FROM PSEUDOMONAS AERUGINOSA
分子名称: AZURIN, COPPER (II) ION
著者Hammann, C, Nar, H, Huber, R, Messerschmidt, A.
登録日1995-10-12
公開日1996-03-08
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献X-ray crystal structure of the two site-specific mutants Ile7Ser and Phe110Ser of azurin from Pseudomonas aeruginosa.
J.Mol.Biol., 255, 1996
7NM2
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Solution structure of MLKL executioner domain in complex with a fragment
分子名称: 2-[(~{S})-methoxy-(4-propan-2-ylphenyl)methyl]-3~{H}-benzimidazole-5-carboxylic acid, Mixed lineage kinase domain-like protein
著者Ruebbelke, M, Bauer, M, Hamilton, J, Binder, F, Nar, H, Zeeb, M.
登録日2021-02-23
公開日2021-09-22
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Discovery and Structure-Based Optimization of Fragments Binding the Mixed Lineage Kinase Domain-like Protein Executioner Domain.
J.Med.Chem., 64, 2021
6Z89
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human GTP cyclohydrolase I in complex with allosteric inhibitor
分子名称: 5-azanyl-[1,3]thiazolo[5,4-d]pyrimidine-2,7-dione, GTP cyclohydrolase 1, ZINC ION
著者Ebenhoch, R, Nar, H.
登録日2020-06-02
公開日2020-12-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.366 Å)
主引用文献A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020

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