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PDB: 17170 results

8V3P
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CCP5 in complex with Glu-P-peptide 2 transition state analog
Descriptor: Cytosolic carboxypeptidase-like protein 5, Tubulin beta-2A chain, ZINC ION
Authors:Chen, J, Zehr, E.A, Gruschus, J.M, Szyk, A, Liu, Y, Tanner, M.E, Tjandra, N, Roll-Mecak, A.
Deposit date:2023-11-28
Release date:2024-07-17
Last modified:2024-08-07
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Tubulin code eraser CCP5 binds branch glutamates by substrate deformation.
Nature, 631, 2024
8V4L
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CCP5 in complex with microtubules class2
Descriptor: Cytosolic carboxypeptidase-like protein 5, GLUTAMIC ACID, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Chen, J, Zehr, E.A, Gruschus, J.M, Szyk, A, Liu, Y, Tanner, M.E, Tjandra, N, Roll-Mecak, A.
Deposit date:2023-11-29
Release date:2024-07-17
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Tubulin code eraser CCP5 binds branch glutamates by substrate deformation.
Nature, 631, 2024
8V3Q
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Structure of CCP5 class1
Descriptor: Cytosolic carboxypeptidase-like protein 5, GLUTAMIC ACID, ZINC ION, ...
Authors:Chen, J, Zehr, E.A, Gruschus, J.M, Szyk, A, Liu, Y, Tanner, M.E, Tjandra, N, Roll-Mecak, A.
Deposit date:2023-11-28
Release date:2024-07-17
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Tubulin code eraser CCP5 binds branch glutamates by substrate deformation.
Nature, 631, 2024
8UXS
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KLHDC2 ubiquitin ligase in complex with a novel small-molecule
Descriptor: Kelch domain-containing protein 2, {4-[(2-{[(4-tert-butylphenyl)methyl]sulfanyl}acetamido)methyl]-1H-1,2,3-triazol-1-yl}acetic acid
Authors:Rusnac, D.V, Zheng, N.
Deposit date:2023-11-10
Release date:2024-07-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:KLHDC2 ubiquitin ligase in complex with a novel small-molecule
To Be Published
7JX3
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Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab domain of monoclonal antibody S2H14, Heavy chain of Fab domain of monoclonal antibody S304, ...
Authors:Snell, G, Czudnochowski, N, Rosen, L.E, Nix, J.C, Corti, D, Veesler, D, Park, Y.J, Walls, A.C, Tortorici, M.A, Cameroni, E, Pinto, D, Beltramello, M, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-08-26
Release date:2020-10-14
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell, 183, 2020
6CBC
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Crystal structure of an N-terminal fragment of Vps13.
Descriptor: Vacuolar protein sorting-associated protein
Authors:Kumar, N, Horenkamp, F.A, Reinisch, K.M.
Deposit date:2018-02-02
Release date:2018-08-08
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites.
J. Cell Biol., 217, 2018
8UG5
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Caenorhabditis elegans Otopetrin 8 (CeOtop8) in pH 5.0
Descriptor: Otopetrin-2
Authors:Gan, N, Jiang, Y.
Deposit date:2023-10-05
Release date:2024-08-21
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024
8UGA
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Mus musculus Otopetrin 2 (mOTOP2) M374W in pH 8.0
Descriptor: Proton channel OTOP2
Authors:Gan, N, Jiang, Y.
Deposit date:2023-10-05
Release date:2024-08-21
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024
8UG4
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Caenorhabditis elegans Otopetrin 8 (CeOtop8) in pH 8.0
Descriptor: Otopetrin-2
Authors:Gan, N, Jiang, Y.
Deposit date:2023-10-05
Release date:2024-08-21
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024
8UG7
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Mus musculus Otopetrin 2 (mOTOP2) in pH 8.0
Descriptor: Proton channel OTOP2
Authors:Gan, N, Jiang, Y.
Deposit date:2023-10-05
Release date:2024-08-21
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024
8UG8
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Mus musculus Otopetrin 2 (mOTOP2) in pH 7.0, intermediate state
Descriptor: Proton channel OTOP2
Authors:Gan, N, Jiang, Y.
Deposit date:2023-10-05
Release date:2024-08-21
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.79 Å)
Cite:Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024
7Z1U
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Biochemical implications of the substitution of a unique cysteine residue in sugar beet phytoglobin BvPgb 1.2
Descriptor: Non-symbiotic hemoglobin class 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Nyblom, M, Christensen, S, Leiva Eriksson, N, Bulow, L.
Deposit date:2022-02-25
Release date:2022-09-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Oxidative Implications of Substituting a Conserved Cysteine Residue in Sugar Beet Phytoglobin BvPgb 1.2.
Antioxidants, 11, 2022
6RV5
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X-ray structure of the levansucrase from Erwinia tasmaniensis in complex with levanbiose
Descriptor: GLYCEROL, Levansucrase (Beta-D-fructofuranosyl transferase), ZINC ION, ...
Authors:Polsinelli, I, Caliandro, R, Demitri, N, Benini, S.
Deposit date:2019-05-31
Release date:2020-04-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:The Structure of Sucrose-Soaked Levansucrase Crystals fromErwinia tasmaniensisreveals a Binding Pocket for Levanbiose.
Int J Mol Sci, 21, 2019
8UPY
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Methanosarcine mazei tRNAPyl in A-site of ribosome
Descriptor: RNA (72-MER)
Authors:Krahn, N, Zhang, J, Melnikov, S.V, Tharp, J.M, Villa, A, Patel, A, Howard, R.J, Gabir, H, Patel, T.R, Stetefeld, J, Puglisi, J, Soll, D.
Deposit date:2023-10-23
Release date:2024-09-04
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:tRNA shape is an identity element for an archaeal pyrrolysyl-tRNA synthetase from the human gut.
Nucleic Acids Res., 52, 2024
8UG6
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Mus musculus Otopetrin 2 (mOTOP2) in pH 5.0
Descriptor: Proton channel OTOP2
Authors:Gan, N, Jiang, Y.
Deposit date:2023-10-05
Release date:2024-08-21
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024
8UEN
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BU of 8uen by Molmil
Crystal structure of Corynebacterium ulcerans endo-beta-N-acetylglucosaminidase catalytically inactive CU43 D187A-E189A at 2.3 A (P 21 21 2)
Descriptor: Corynebacterial protease CP40
Authors:Sastre, D.E, Sultana, N, Sundberg, E.J.
Deposit date:2023-10-02
Release date:2024-10-16
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Potent efficacy of an IgG-specific endoglycosidase against IgG-mediated pathologies
Cell(Cambridge,Mass.), 2024
6CMO
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Rhodopsin-Gi complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Heavy chain, Fab light chain, ...
Authors:Kang, Y, Kuybeda, O, de Waal, P.W, Mukherjee, S, Van Eps, N, Dutka, P, Zhou, X.E, Bartesaghi, A, Erramilli, S, Morizumi, T, Gu, X, Yin, Y, Liu, P, Jiang, Y, Meng, X, Zhao, G, Melcher, K, Earnst, O.P, Kossiakoff, A.A, Subramaniam, S, Xu, H.E.
Deposit date:2018-03-05
Release date:2018-06-20
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.
Nature, 558, 2018
6RHY
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Structure of pore-forming amyloid-beta tetramers
Descriptor: Amyloid beta A4 protein
Authors:Bardiaux, B, Ciudad, S, Carulla, N.
Deposit date:2019-04-23
Release date:2019-09-25
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:A beta (1-42) tetramer and octamer structures reveal edge conductivity pores as a mechanism for membrane damage.
Nat Commun, 11, 2020
6CO9
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Crystal structure of Rhodococcus jostii RHA1 IpdAB COCHEA-COA complex
Descriptor: Probable CoA-transferase alpha subunit, Probable CoA-transferase beta subunit, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (5R,10R)-7-hydroxy-10-methyl-2-oxo-1-oxaspiro[4.5]dec-6-ene-6-carbothioate (non-preferred name), ...
Authors:Crowe, A.M, Workman, S.D, Watanabe, N, Worrall, L.J, Strynadka, N.C.J, Eltis, L.D.
Deposit date:2018-03-12
Release date:2018-03-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:IpdAB, a virulence factor inMycobacterium tuberculosis, is a cholesterol ring-cleaving hydrolase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8V5L
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Structure of the Varicella Zoster Virus (VZV) gI binding domain of glycoprotein E (gE) in complex with human Fab 1A2 and 1E12
Descriptor: Envelope glycoprotein E, Fab 1A2 Heavy Chain, Fab 1A2 Light Chain, ...
Authors:Seraj, N, Holzapfel, G, Harshbarger, W.
Deposit date:2023-11-30
Release date:2024-10-09
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Structures of the Varicella Zoster Virus Glycoprotein E and Epitope Mapping of Vaccine-Elicited Antibodies
Vaccines (Basel), 12, 2024
6CQI
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2.42A Crystal structure of Mycobacterium tuberculosis Topoisomerase I in complex with an oligonucleotide MTS2-11
Descriptor: ACETATE ION, DNA (5'-D(P*TP*TP*CP*CP*GP*CP*TP*TP*GP*A)-3'), DNA topoisomerase 1, ...
Authors:Cao, N, Thirunavukkarasu, A, Tan, K, Tse-Dinh, Y.-C.
Deposit date:2018-03-15
Release date:2018-05-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Investigating mycobacterial topoisomerase I mechanism from the analysis of metal and DNA substrate interactions at the active site.
Nucleic Acids Res., 46, 2018
6COJ
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Crystal structure of Rhodococcus jostii RHA1 IpdAB E105A COCHEA-COA complex
Descriptor: Probable CoA-transferase alpha subunit, Probable CoA-transferase beta subunit, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (5R,10R)-7-hydroxy-10-methyl-2-oxo-1-oxaspiro[4.5]dec-6-ene-6-carbothioate (non-preferred name), ...
Authors:Crowe, A.M, Workman, S.D, Watanabe, N, Worrall, L.J, Strynadka, N.C.J, Eltis, L.D.
Deposit date:2018-03-12
Release date:2018-03-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:IpdAB, a virulence factor inMycobacterium tuberculosis, is a cholesterol ring-cleaving hydrolase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CQ2
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Crystal structure of Mycobacterium tuberculosis Topoisomerase I in complex with oligonucleotide MTS2-12 and Magnesium
Descriptor: DNA (5'-D(P*TP*TP*CP*CP*GP*CP*TP*TP*GP*A)-3'), DNA topoisomerase 1, MAGNESIUM ION, ...
Authors:Cao, N, Thirunavukkaraus, A, Tan, K, Tse-Dinh, Y.-C.
Deposit date:2018-03-14
Release date:2018-05-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.004 Å)
Cite:Investigating mycobacterial topoisomerase I mechanism from the analysis of metal and DNA substrate interactions at the active site.
Nucleic Acids Res., 46, 2018
6CRZ
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SARS Spike Glycoprotein, Trypsin-cleaved, Stabilized variant, C3 symmetry
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ...
Authors:Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
8URA
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BU of 8ura by Molmil
Crystal structure of Corynebacterium ulcerans endo-beta-N-acetylglucosaminidase catalytically inactive CU43 D187A-E189A at 2.6 A resolution (space group P21)
Descriptor: Corynebacterial protease CP40
Authors:Sastre, D.E, Sultana, N, Sundberg, E.J.
Deposit date:2023-10-25
Release date:2024-10-23
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Potent efficacy of an IgG-specific endoglycosidase against IgG-mediated pathologies
Cell(Cambridge,Mass.), 2024

226707

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