8V3Q

Structure of CCP5 class1

Summary for 8V3Q

• Entry DOI: 10.2210/pdb8v3q/pdb
• EMDB information: 42950
• Descriptor: Cytosolic carboxypeptidase-like protein 5, beta tubulin tail, ZINC ION, ... (4 entities in total)
• Functional Keywords: carboxypeptidase, deglutamylation, branch glutamate removal, microtubule, hydrolase, hydrolase-substrate complex, hydrolase/substrate
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 69270.05

Authors

Chen, J.,Zehr, E.A.,Gruschus, J.M.,Szyk, A.,Liu, Y.,Tanner, M.E.,Tjandra, N.,Roll-Mecak, A. (deposition date: 2023-11-28, release date: 2024-07-17)

• Primary citation: Chen, J.,Zehr, E.A.,Gruschus, J.M.,Szyk, A.,Liu, Y.,Tanner, M.E.,Tjandra, N.,Roll-Mecak, A.; Tubulin code eraser CCP5 binds branch glutamates by substrate deformation; Nature, 2024; DOI: 10.1038/s41586-024-07699-0

Experimental method

ELECTRON MICROSCOPY (3.1 Å)