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PDB: 17048 件
6SGY
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Structure of EccB3 dimer from the ESX-3 core complex
分子名称: ESX-3 secretion system protein EccB3
著者Famelis, N, Rivera-Calzada, A, Llorca, O, Geibel, S.
登録日2019-08-05
公開日2019-10-09
最終更新日2019-12-25
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Architecture of the mycobacterial type VII secretion system.
Nature, 576, 2019
6SGW
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Structure of the ESX-3 core complex
分子名称: ESX-3 secretion system ATPase EccB3, ESX-3 secretion system protein EccC3, ESX-3 secretion system protein EccD3, ...
著者Famelis, N, Rivera-Calzada, A, Llorca, O, Geibel, S.
登録日2019-08-05
公開日2019-10-09
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Architecture of the mycobacterial type VII secretion system.
Nature, 576, 2019
5Y7Z
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Complex structure of cyclin G-associated kinase with gefitinib
分子名称: Cyclin-G-associated kinase, Gefitinib, NANOBODY, ...
著者Ohbayashi, N, Murayama, K, Kato-Murayama, M, Shirouzu, M.
登録日2017-08-18
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.804 Å)
主引用文献Structural Basis for the Inhibition of Cyclin G-Associated Kinase by Gefitinib.
ChemistryOpen, 7, 2018
6SGZ
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Structure of protomer 2 of the ESX-3 core complex
分子名称: ESX-3 secretion system ATPase EccB3, ESX-3 secretion system protein EccC3, ESX-3 secretion system protein EccD3, ...
著者Famelis, N, Rivera-Calzada, A, Llorca, O, Geibel, S.
登録日2019-08-05
公開日2019-10-09
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Architecture of the mycobacterial type VII secretion system.
Nature, 576, 2019
5W8M
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Crystal structure of Chaetomium thermophilum Vps29
分子名称: GLYCEROL, TRIETHYLENE GLYCOL, Vacuolar protein sorting-associated protein 29
著者Collins, B.M, Leneva, N.
登録日2017-06-21
公開日2018-06-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Structure of the membrane-assembled retromer coat determined by cryo-electron tomography.
Nature, 561, 2018
7JRJ
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Chlamydomonas reinhardtii radial spoke head and neck (recombinant)
分子名称: Flagellar radial spoke protein 1, Flagellar radial spoke protein 10, Flagellar radial spoke protein 2, ...
著者Grossman-Haham, I, Coudray, N, Yu, Z, Wang, F, Zhang, N, Bhabha, G, Vale, R.D.
登録日2020-08-12
公開日2020-12-16
最終更新日2021-01-27
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structure of the radial spoke head and insights into its role in mechanoregulation of ciliary beating.
Nat.Struct.Mol.Biol., 28, 2021
5YJO
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Crystal structure of SmyD3 in complex with covalent inhibitor 4
分子名称: Histone-lysine N-methyltransferase SMYD3, S-ADENOSYLMETHIONINE, ZINC ION, ...
著者Baburajendran, N, Anna E, J.
登録日2017-10-11
公開日2018-10-17
最終更新日2019-07-10
実験手法X-RAY DIFFRACTION (2.135 Å)
主引用文献Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3.
Acs Med.Chem.Lett., 10, 2019
6SWZ
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Structure of the C-terminal domain of C. glutamicum mycoloyltransferase A
分子名称: GLYCEROL, Protein PS1
著者Li de la Sierra-Gallay, I, Van tilbeurgh, H, Bayan, N.
登録日2019-09-24
公開日2020-03-04
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.995 Å)
主引用文献The C-terminal domain of Corynebacterium glutamicum mycoloyltransferase A is composed of five repeated motifs involved in cell wall binding and stability.
Mol.Microbiol., 114, 2020
6SF7
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Atomic resolution structure of SplF protease from Staphylococcus aureus
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, SULFATE ION, ...
著者Golik, P, Stach, N, Karim, A, Dubin, G.
登録日2019-08-01
公開日2021-03-03
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Determinants of Substrate Specificity of SplF Protease from Staphylococcus aureus .
Int J Mol Sci, 22, 2021
5Y6U
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Crystal structure of wild-type YabJ protein from Bacillus subtilis (natto).
分子名称: ACETIC ACID, YabJ protein
著者Fujimoto, Z, Kishine, N, Kimura, K.
登録日2017-08-15
公開日2018-08-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Tetramer formation of Bacillus subtilis YabJ protein that belongs to YjgF/YER057c/UK114 family.
Biosci.Biotechnol.Biochem., 85, 2021
5Y80
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Complex structure of cyclin G-associated kinase with gefitinib
分子名称: Cyclin-G-associated kinase, Gefitinib, NANOBODY
著者Ohbayashi, N, Murayama, K, Kato-Murayama, M, Shirouzu, M.
登録日2017-08-18
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for the Inhibition of Cyclin G-Associated Kinase by Gefitinib.
ChemistryOpen, 7, 2018
5YE5
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structure of endo-lysosomal TRPML1 channel inserting into nanodisc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, mammalian endo-lysosomal TRPML1 channel
著者Yang, M, Gao, N.
登録日2017-09-15
公開日2017-11-15
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
Protein Cell, 8, 2017
5X02
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Crystal structure of the FLT3 kinase domain bound to the inhibitor FF-10101
分子名称: N-[(2S)-1-[5-[2-[(4-cyanophenyl)amino]-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxidanylidene-propan-2-yl]-4-(dimethylamino)-N-methyl-but-2-enamide, Receptor-type tyrosine-protein kinase FLT3, SULFATE ION
著者Fujikawa, N, Hirano, D, Takasaki, M, Terada, D, Hagiwara, S, Park, S.-Y, Sugiyama, K.
登録日2017-01-19
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献A novel irreversible FLT3 inhibitor, FF-10101, shows excellent efficacy against AML cells withFLT3mutations.
Blood, 131, 2018
5YDZ
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structure of endo-lysosomal TRPML1 channel inserting into amphipol: state 1
分子名称: mammalian endo-lysosomal TRPML1 channel
著者Yang, M, Gao, N.
登録日2017-09-15
公開日2017-12-27
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
Protein Cell, 8, 2017
8IMZ
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Cryo-EM structure of mouse Piezo1-MDFIC complex (composite map)
分子名称: MyoD family inhibitor domain-containing protein, Piezo-type mechanosensitive ion channel component 1
著者Zhou, Z, Ma, X, Lin, Y, Cheng, D, Bavi, N, Li, J.V, Sutton, D, Yao, M, Harvey, N, Corry, B, Zhang, Y, Cox, C.D.
登録日2023-03-07
公開日2023-08-09
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献MyoD-family inhibitor proteins act as auxiliary subunits of Piezo channels.
Science, 381, 2023
6SX4
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Structure of C. glutamicum mycoloyltransferase A
分子名称: ACETATE ION, Protein PS1
著者Li de la Sierra-Gallay, I, Van tilbeurgh, H, Bayan, N.
登録日2019-09-24
公開日2020-03-04
最終更新日2020-07-22
実験手法X-RAY DIFFRACTION (2.796 Å)
主引用文献The C-terminal domain of Corynebacterium glutamicum mycoloyltransferase A is composed of five repeated motifs involved in cell wall binding and stability.
Mol.Microbiol., 114, 2020
5XJA
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The Crystal Structure of the Minimal Core Domain of the Microtubule Depolymerizer KIF2C Complexed with ADP-Mg-AlFx
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Kinesin-like protein KIF2C, ...
著者Ogawa, T, Jiang, X, Hirokawa, N.
登録日2017-04-30
公開日2017-09-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.43 Å)
主引用文献Mechanism of Catalytic Microtubule Depolymerization via KIF2-Tubulin Transitional Conformation
Cell Rep, 20, 2017
6BX8
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Human Mesotrypsin (PRSS3) Complexed with Tissue Factor Pathway Inhibitor Variant (TFPI1-KD1-K15R-I17C-I34C)
分子名称: SULFATE ION, Tissue factor pathway inhibitor, Trypsin-3
著者Coban, M, Sankaran, B, Cohen, I, Hockla, A, Papo, N, Radisky, E.S.
登録日2017-12-18
公開日2019-02-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin.
J. Biol. Chem., 294, 2019
5XJB
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The Crystal Structure of the Minimal Core Domain of the Microtubule Depolymerizer KIF2C Complexed with ADP-Mg-BeFx
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Kinesin-like protein KIF2C, ...
著者Ogawa, T, Jiang, X, Hirokawa, N.
登録日2017-04-30
公開日2017-09-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Mechanism of Catalytic Microtubule Depolymerization via KIF2-Tubulin Transitional Conformation
Cell Rep, 20, 2017
8U7Z
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KCTD5/Cullin3/Gbeta1gamma2 Complex: Local Refinment of KCTD5(CTD)/Gbeta1gamma2
分子名称: BTB/POZ domain-containing protein KCTD5, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
著者Kuntz, D.A, Nguyen, D.M, Narayanan, N, Prive, G.G.
登録日2023-09-15
公開日2023-10-11
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structure and dynamics of a pentameric KCTD5/CUL3/G beta gamma E3 ubiquitin ligase complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8U82
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KCTD5/Cullin3/Gbeta1gamma2 Complex: State B From Composite RELION Multi-body Refinement Map
分子名称: BTB/POZ domain-containing protein KCTD5, Cullin-3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Kuntz, D.A, Nguyen, D.M, Narayanan, N, Prive, G.G.
登録日2023-09-15
公開日2023-10-11
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Structure and dynamics of a pentameric KCTD5/CUL3/G beta gamma E3 ubiquitin ligase complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8U81
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KCTD5/Cullin3/Gbeta1gamma2 Complex: State A From Composite RELION Multi-body Refinement Map
分子名称: BTB/POZ domain-containing protein KCTD5, Cullin-3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Kuntz, D.A, Nguyen, D.M, Narayanan, N, Prive, G.G.
登録日2023-09-15
公開日2023-10-11
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.82 Å)
主引用文献Structure and dynamics of a pentameric KCTD5/CUL3/G beta gamma E3 ubiquitin ligase complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8U83
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KCTD5/Cullin3/Gbeta1gamma2 Complex: State C From Composite RELION Multi-body Refinement Map
分子名称: BTB/POZ domain-containing protein KCTD5, Cullin-3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Kuntz, D.A, Nguyen, D.M, Narayanan, N, Prive, G.G.
登録日2023-09-15
公開日2023-10-11
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.975 Å)
主引用文献Structure and dynamics of a pentameric KCTD5/CUL3/G beta gamma E3 ubiquitin ligase complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8U80
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KCTD5/Cullin3/Gbeta1gamma2 Complex: Local Refinment of KCTD5(BTB)/Cullin3(NTD)
分子名称: BTB/POZ domain-containing protein KCTD5, Cullin-3
著者Kuntz, D.A, Nguyen, D.M, Narayanan, N, Prive, G.G.
登録日2023-09-15
公開日2023-10-11
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure and dynamics of a pentameric KCTD5/CUL3/G beta gamma E3 ubiquitin ligase complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8U84
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KCTD5/Cullin3/Gbeta1gamma2 Complex: State D From Composite RELION Multi-body Refinement Map
分子名称: BTB/POZ domain-containing protein KCTD5, Cullin-3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Kuntz, D.A, Nguyen, D.M, Narayanan, N, Prive, G.G.
登録日2023-09-15
公開日2023-10-11
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.88 Å)
主引用文献Structure and dynamics of a pentameric KCTD5/CUL3/G beta gamma E3 ubiquitin ligase complex.
Proc.Natl.Acad.Sci.USA, 121, 2024

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件を2024-08-21に公開中

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