8IMZ

Cryo-EM structure of mouse Piezo1-MDFIC complex (composite map)

Summary for 8IMZ

• Entry DOI: 10.2210/pdb8imz/pdb
• EMDB information: 35577 36241 36242 36243 36244
• Descriptor: Piezo-type mechanosensitive ion channel component 1, MyoD family inhibitor domain-containing protein (2 entities in total)
• Functional Keywords: piezo1 complex, mechanosensation, mechanotransduction, membrane protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 6
• Total formula weight: 955330.16

Authors

Zhou, Z.,Ma, X.,Lin, Y.,Cheng, D.,Bavi, N.,Li, J.V.,Sutton, D.,Yao, M.,Harvey, N.,Corry, B.,Zhang, Y.,Cox, C.D. (deposition date: 2023-03-07, release date: 2023-08-09, Last modification date: 2023-08-30)

• Primary citation: Zhou, Z.,Ma, X.,Lin, Y.,Cheng, D.,Bavi, N.,Secker, G.A.,Li, J.V.,Janbandhu, V.,Sutton, D.L.,Scott, H.S.,Yao, M.,Harvey, R.P.,Harvey, N.L.,Corry, B.,Zhang, Y.,Cox, C.D.; MyoD-family inhibitor proteins act as auxiliary subunits of Piezo channels.; Science, 381:799-804, 2023; PubMed: 37590348; DOI: 10.1126/science.adh8190

Experimental method

ELECTRON MICROSCOPY (3.66 Å)