5XJB

The Crystal Structure of the Minimal Core Domain of the Microtubule Depolymerizer KIF2C Complexed with ADP-Mg-BeFx

Summary for 5XJB

Entry DOI	10.2210/pdb5xjb/pdb
Descriptor	Kinesin-like protein KIF2C, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... (5 entities in total)
Functional Keywords	kinesin, microtubule, tubulin, kif2, mcak, depolymerization, structural protein
Biological source	Mus musculus (Mouse)
Cellular location	Cytoplasm, cytoskeleton : Q922S8
Total number of polymer chains	2
Total formula weight	97942.11
Authors	Ogawa, T.,Jiang, X.,Hirokawa, N. (deposition date: 2017-04-30, release date: 2017-09-13, Last modification date: 2023-11-22)
Primary citation	Ogawa, T.,Saijo, S.,Shimizu, N.,Jiang, X.,Hirokawa, N. Mechanism of Catalytic Microtubule Depolymerization via KIF2-Tubulin Transitional Conformation Cell Rep, 20:2626-2638, 2017 Cited by PubMed: 28903043 DOI: 10.1016/j.celrep.2017.08.067 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation