5Y80

Complex structure of cyclin G-associated kinase with gefitinib

Summary for 5Y80

• Entry DOI: 10.2210/pdb5y80/pdb
• Descriptor: Cyclin-G-associated kinase, NANOBODY, Gefitinib, ... (4 entities in total)
• Functional Keywords: kinase, complex, transferase-immune system complex, transferase/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 52741.30

Authors

Ohbayashi, N.,Murayama, K.,Kato-Murayama, M.,Shirouzu, M. (deposition date: 2017-08-18, release date: 2018-08-29, Last modification date: 2023-11-22)

• Primary citation: Ohbayashi, N.,Murayama, K.,Kato-Murayama, M.,Kukimoto-Niino, M.,Uejima, T.,Matsuda, T.,Ohsawa, N.,Yokoyoma, S.,Nojima, H.,Shirouzu, M.; Structural Basis for the Inhibition of Cyclin G-Associated Kinase by Gefitinib.; ChemistryOpen, 7:721-727, 2018; PubMed: 30214852; DOI: 10.1002/open.201800177

Experimental method

X-RAY DIFFRACTION (2.5 Å)