5Y80
Complex structure of cyclin G-associated kinase with gefitinib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cyclin-G-associated kinase | polymer | 313 | 35657.8 | 1 | UniProt (O14976) Pfam (PF00069) | Homo sapiens (Human) | |
| 2 | B (B) | NANOBODY | polymer | 148 | 16189.7 | 1 | Lama glama | ||
| 3 | C, D (A) | Gefitinib | non-polymer | 446.9 | 2 | Chemie (IRE) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A: 25 - 335 (UniProt: O14976)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
| Ser 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51847.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 893.8 | |
| All* | Total formula weight | 52741.3 |
