1BAG
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![BU of 1bag by Molmil](/molmil-images/mine/1bag) | ALPHA-AMYLASE FROM BACILLUS SUBTILIS COMPLEXED WITH MALTOPENTAOSE | Descriptor: | ALPHA-1,4-GLUCAN-4-GLUCANOHYDROLASE, CALCIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose | Authors: | Fujimoto, Z, Mizuno, H, Takase, K, Doui, N. | Deposit date: | 1998-01-30 | Release date: | 1998-10-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of a catalytic-site mutant alpha-amylase from Bacillus subtilis complexed with maltopentaose. J.Mol.Biol., 277, 1998
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1BCG
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![BU of 1bcg by Molmil](/molmil-images/mine/1bcg) | SCORPION TOXIN BJXTR-IT | Descriptor: | TOXIN BJXTR-IT | Authors: | Oren, D, Froy, O, Amit, E, Kleinberger-Doron, N, Gurevitz, M, Shaanan, B. | Deposit date: | 1998-04-29 | Release date: | 1998-11-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | An excitatory scorpion toxin with a distinctive feature: an additional alpha helix at the C terminus and its implications for interaction with insect sodium channels. Structure, 6, 1998
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6WX7
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![BU of 6wx7 by Molmil](/molmil-images/mine/6wx7) | SOX2 bound to Importin-alpha 2 | Descriptor: | Importin subunit alpha-1, Transcription factor SOX-2 | Authors: | Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N. | Deposit date: | 2020-05-09 | Release date: | 2020-10-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for nuclear import selectivity of pioneer transcription factor SOX2. Nat Commun, 12, 2021
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1MJU
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![BU of 1mju by Molmil](/molmil-images/mine/1mju) | 1.22 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF ESTEROLYTIC ANTIBODY MS6-12 | Descriptor: | GLYCEROL, IMMUNOGLOBULIN MS6-12 | Authors: | Ruzheinikov, S.N, Muranova, T.A, Sedelnikova, S.E, Partridge, L.J, Blackburn, G.M, Murray, I.A, Kakinuma, H, Takashi, N, Shimazaki, K, Sun, J, Nishi, Y, Rice, D.W. | Deposit date: | 2002-08-28 | Release date: | 2003-09-23 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | High-resolution crystal structure of the Fab-fragments of a family of mouse catalytic antibodies with esterase activity J.Mol.Biol., 332, 2003
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6X4I
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![BU of 6x4i by Molmil](/molmil-images/mine/6x4i) | Crystal Structure of NSP15 Endoribonuclease from SARS CoV-2 in the Complex with 3'-uridinemonophosphate | Descriptor: | 1,2-ETHANEDIOL, 3'-URIDINEMONOPHOSPHATE, SODIUM ION, ... | Authors: | Chang, C, Kim, Y, Maltseva, N, Jedrzejczak, R, Endres, M, Michalska, K, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-05-22 | Release date: | 2020-06-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2. Commun Biol, 4, 2021
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5MHF
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![BU of 5mhf by Molmil](/molmil-images/mine/5mhf) | Murine endoplasmic reticulum alpha-glucosidase I with N-9'-methoxynonyl-1-deoxynojirimycin. | Descriptor: | 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mannosyl-oligosaccharide glucosidase, ... | Authors: | Hill, J.C, Caputo, A.T, Roversi, P, Zitzmann, N. | Deposit date: | 2016-11-24 | Release date: | 2017-12-20 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Targeting Endoplasmic Reticulum alpha-Glucosidase I with a Single-Dose Iminosugar Treatment Protects against Lethal Influenza and Dengue Virus Infections. J.Med.Chem., 2020
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1MO3
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1A1S
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![BU of 1a1s by Molmil](/molmil-images/mine/1a1s) | ORNITHINE CARBAMOYLTRANSFERASE FROM PYROCOCCUS FURIOSUS | Descriptor: | ORNITHINE CARBAMOYLTRANSFERASE | Authors: | Villeret, V, Clantin, B, Tricot, C, Legrain, C, Roovers, M, Stalon, V, Glansdorff, N, Van Beeumen, J. | Deposit date: | 1997-12-15 | Release date: | 1998-06-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The crystal structure of Pyrococcus furiosus ornithine carbamoyltransferase reveals a key role for oligomerization in enzyme stability at extremely high temperatures. Proc.Natl.Acad.Sci.USA, 95, 1998
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2PQ5
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![BU of 2pq5 by Molmil](/molmil-images/mine/2pq5) | Crystal structure of Dual specificity protein phosphatase 13 (DUSP13) | Descriptor: | Dual specificity protein phosphatase 13 | Authors: | Ugochukwu, E, Salah, E, Savitsky, P, Barr, A, Pantic, N, Niesen, F, Burgess-Brown, N, Berridge, G, Bunkoczi, G, Uppenberg, J, Pike, A.C.W, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2007-05-01 | Release date: | 2007-05-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of Dual specificity protein phosphatase 13 (DUSP13). To be Published
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6WX8
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![BU of 6wx8 by Molmil](/molmil-images/mine/6wx8) | SOX2 bound to Importin-alpha 3 | Descriptor: | Importin subunit alpha-3, SULFATE ION, Transcription factor SOX-2 | Authors: | Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N. | Deposit date: | 2020-05-10 | Release date: | 2020-10-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for nuclear import selectivity of pioneer transcription factor SOX2. Nat Commun, 12, 2021
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2OC8
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![BU of 2oc8 by Molmil](/molmil-images/mine/2oc8) | Structure of Hepatitis C Viral NS3 protease domain complexed with NS4A peptide and ketoamide SCH503034 | Descriptor: | BETA-MERCAPTOETHANOL, Hepatitis C virus, ZINC ION, ... | Authors: | Prongay, A.J, Guo, Z, Yao, N, Fischmann, T, Strickland, C, Myers, J, Weber, P.C, Malcolm, B, Beyer, B.M, Ingram, R, Pichardo, J, Hong, Z, Prosise, W.W, Ramanathan, L, Taremi, S.S, Yarosh-Tomaine, T, Zhang, R, Senior, M, Yang, R.S, Arasappan, A, Bennett, F, Bogen, S.L, Chen, K, Jao, E, Liu, Y.T, Lovey, R.G, Saksena, A.K, Venkatraman, S, Girijavallabhan, V, Njoroge, F.G, Madison, V. | Deposit date: | 2006-12-20 | Release date: | 2007-07-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization. J.Med.Chem., 50, 2007
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6WU2
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![BU of 6wu2 by Molmil](/molmil-images/mine/6wu2) | Structure of the LaINDY-malate complex | Descriptor: | DASS family sodium-coupled anion symporter, DECANE, HEXANE, ... | Authors: | Sauer, D.B, Marden, J.J, Cocco, N, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2020-05-04 | Release date: | 2020-09-16 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Structural basis for the reaction cycle of DASS dicarboxylate transporters. Elife, 9, 2020
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6X1B
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![BU of 6x1b by Molmil](/molmil-images/mine/6x1b) | Crystal Structure of NSP15 Endoribonuclease from SARS CoV-2 in the Complex with the Product Nucleotide GpU. | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-R(*GP*U)-3'), PHOSPHATE ION, ... | Authors: | Kim, Y, Maltseva, N, Jedrzejczak, R, Welk, L, Endres, M, Chang, C, Michalska, K, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-05-18 | Release date: | 2020-05-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2. Commun Biol, 4, 2021
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1D78
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![BU of 1d78 by Molmil](/molmil-images/mine/1d78) | HIGH RESOLUTION REFINEMENT OF THE HEXAGONAL A-DNA OCTAMER D(GTGTACAC) AT 1.4 ANGSTROMS RESOLUTION | Descriptor: | DNA (5'-D(*GP*TP*GP*TP*AP*CP*AP*C)-3') | Authors: | Thota, N, Li, X.H, Bingman, C.A, Sundaralingam, M. | Deposit date: | 1992-06-12 | Release date: | 1993-04-15 | Last modified: | 2023-03-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | High-resolution refinement of the hexagonal A-DNA octamer d(GTGTACAC) at 1.4 A. Acta Crystallogr.,Sect.D, 49, 1993
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6WEY
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6WTW
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![BU of 6wtw by Molmil](/molmil-images/mine/6wtw) | Structure of LaINDY crystallized in the presence of alpha-ketoglutarate and malate | Descriptor: | DASS family sodium-coupled anion symporter | Authors: | Sauer, D.B, Cocco, N, Marden, J.J, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2020-05-04 | Release date: | 2020-09-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Structural basis for the reaction cycle of DASS dicarboxylate transporters. Elife, 9, 2020
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6I5C
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![BU of 6i5c by Molmil](/molmil-images/mine/6i5c) | Long wavelength native-SAD phasing of Tubulin-Stathmin-TTL complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Basu, S, Olieric, V, Matsugaki, N, Kawano, Y, Takashi, T, Huang, C.Y, Leonarski, F, Yamada, Y, Vera, L, Olieric, N, Basquin, J, Wojdyla, J.A, Diederichs, K, Yamamoto, M, Bunk, O, Wang, M. | Deposit date: | 2018-11-13 | Release date: | 2019-03-13 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Long-wavelength native-SAD phasing: opportunities and challenges. Iucrj, 6, 2019
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5GJI
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![BU of 5gji by Molmil](/molmil-images/mine/5gji) | PI3K p85 N-terminal SH2 domain/CD28-derived peptide complex | Descriptor: | GLYCEROL, Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION, ... | Authors: | Inaba, S, Numoto, N, Morii, H, Ogawa, S, Ikura, T, Abe, R, Ito, N, Oda, M. | Deposit date: | 2016-06-30 | Release date: | 2016-12-14 | Last modified: | 2017-05-10 | Method: | X-RAY DIFFRACTION (0.9 Å) | Cite: | Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins J. Biol. Chem., 292, 2017
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5MWU
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![BU of 5mwu by Molmil](/molmil-images/mine/5mwu) | Crystal structure of the periplasmic nickel-binding protein NikA from Escherichia coli in complex with Ru(bpza)(CO)2Cl | Descriptor: | ACETATE ION, CARBON MONOXIDE, CHLORIDE ION, ... | Authors: | Cavazza, C, Lopez, S, Rondot, L, Iannello, M, Boeri-Erba, E, Burzlaff, N, Strinitz, F, Jorge-Robin, A, Marchi-Delapierre, C, Menage, S. | Deposit date: | 2017-01-20 | Release date: | 2017-02-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Efficient conversion of alkenes to chlorohydrins by a Ru-based artificial enzyme To Be Published
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1D7F
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![BU of 1d7f by Molmil](/molmil-images/mine/1d7f) | CRYSTAL STRUCTURE OF ASPARAGINE 233-REPLACED CYCLODEXTRIN GLUCANOTRANSFERASE FROM ALKALOPHILIC BACILLUS SP. 1011 DETERMINED AT 1.9 A RESOLUTION | Descriptor: | CALCIUM ION, CYCLODEXTRIN GLUCANOTRANSFERASE | Authors: | Ishii, N, Haga, K, Yamane, K, Harata, K. | Deposit date: | 1999-10-18 | Release date: | 2000-03-17 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of asparagine 233-replaced cyclodextrin glucanotransferase from alkalophilic Bacillus sp. 1011 determined at 1.9 A resolution. J.Mol.Recog., 13, 2000
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5GJH
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![BU of 5gjh by Molmil](/molmil-images/mine/5gjh) | Gads SH2 domain/CD28-derived peptide complex | Descriptor: | GRB2-related adapter protein 2, T-cell-specific surface glycoprotein CD28 | Authors: | Inaba, S, Numoto, N, Morii, H, Ogawa, S, Ikura, T, Abe, R, Ito, N, Oda, M. | Deposit date: | 2016-06-30 | Release date: | 2016-12-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins J. Biol. Chem., 292, 2017
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5GTF
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![BU of 5gtf by Molmil](/molmil-images/mine/5gtf) | Crystal structure of onion lachrymatory factor synthase (LFS) containing glycerol | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Lachrymatory-factor synthase, ... | Authors: | Takabe, J, Arakawa, T, Masamura, N, Tsuge, N, Imai, S, Fushinobu, S. | Deposit date: | 2016-08-20 | Release date: | 2017-08-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Dissecting the Stereocontrolled Conversion of Short-Lived Sulfenic Acid by Lachrymatory Factor Synthase Acs Catalysis, 10, 2020
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6WU4
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![BU of 6wu4 by Molmil](/molmil-images/mine/6wu4) | Structure of the LaINDY-alpha-ketoglutarate complex | Descriptor: | DASS family sodium-coupled anion symporter | Authors: | Sauer, D.B, Marden, J.J, Cocco, N, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2020-05-04 | Release date: | 2020-09-16 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.71 Å) | Cite: | Structural basis for the reaction cycle of DASS dicarboxylate transporters. Elife, 9, 2020
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1PHR
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![BU of 1phr by Molmil](/molmil-images/mine/1phr) | THE CRYSTAL STRUCTURE OF A LOW MOLECULAR PHOSPHOTYROSINE PROTEIN PHOSPHATASE | Descriptor: | LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE, SULFATE ION | Authors: | Su, X.-D, Taddei, N, Stefani, M, Ramponi, G, Nordlund, P. | Deposit date: | 1994-07-05 | Release date: | 1995-07-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of a low-molecular-weight phosphotyrosine protein phosphatase. Nature, 370, 1994
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6NZ8
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![BU of 6nz8 by Molmil](/molmil-images/mine/6nz8) | Structure of carbamylated apo OXA-231 carbapenemase | Descriptor: | Beta-lactamase OXA-231, CHLORIDE ION, SODIUM ION | Authors: | Favaro, D.C, Llontop, E.E, Vasconcelos, F.N, Antunes, V.U, Farah, S.C, Lincopan, N. | Deposit date: | 2019-02-13 | Release date: | 2020-02-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Importance of the beta 5-beta 6 Loop for the Structure, Catalytic Efficiency, and Stability of Carbapenem-Hydrolyzing Class D beta-Lactamase Subfamily OXA-143. Biochemistry, 58, 2019
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