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PDB: 48 件

2W6K
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The crystal structure at 1.7 A resolution of CobE, a protein from the cobalamin (vitamin B12) biosynthetic pathway
分子名称: COBE, GLYCEROL, SULFATE ION
著者Vevodova, J, Smith, D, McGoldrick, H, Deery, E, Murzin, A.G, Warren, M.J, Wilson, K.S.
登録日2008-12-18
公開日2008-12-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Crystal Structure at 1.7 A Resolution of Cobe, a Protein from the Cobalamin (Vitamin B12) Biosynthetic Pathway
To be Published
1AP0
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STRUCTURE OF THE CHROMATIN BINDING (CHROMO) DOMAIN FROM MOUSE MODIFIER PROTEIN 1, NMR, 26 STRUCTURES
分子名称: MODIFIER PROTEIN 1
著者Ball, L.J, Murzina, N.V, Broadhurst, R.W, Raine, A.R.C, Archer, S.J, Stott, F.J, Murzin, A.G, Singh, P.B, Domaille, P.J, Laue, E.D.
登録日1997-07-22
公開日1998-07-22
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the chromatin binding (chromo) domain from mouse modifier protein 1.
EMBO J., 16, 1997
2BUD
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The solution structure of the chromo barrel domain from the males- absent on the first (MOF) protein
分子名称: MALES-ABSENT ON THE FIRST PROTEIN
著者Nielsen, P.R, Nietlispach, D, Buscaino, A, Warner, R.J, Akhtar, A, Murzin, A.G, Murzina, N.V, Laue, E.D.
登録日2005-06-09
公開日2005-06-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of the Chromo Barrel Domain from the Mof Acetyltransferase
J.Biol.Chem., 280, 2005
8A9L
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Cryo-EM structure of alpha-synuclein filaments from Parkinson's disease and dementia with Lewy bodies
分子名称: Alpha-synuclein, Unknown fragment
著者Yang, Y, Shi, Y, Schweighauser, M, Zhang, X.J, Kotecha, A, Murzin, A.G, Garringer, H.J, Cullinane, P, Saito, Y, Foroud, T, Warner, T.T, Hasegawa, K, Vidal, R, Murayama, S, Revesz, T, Ghetti, B, Hasegawa, M, Lashley, T, Scheres, H.W.S, Goedert, M.
登録日2022-06-28
公開日2022-08-31
最終更新日2022-11-09
実験手法ELECTRON MICROSCOPY (2.16 Å)
主引用文献Structures of alpha-synuclein filaments from human brains with Lewy pathology.
Nature, 610, 2022
6NWP
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Chronic traumatic encephalopathy Type I Tau filament
分子名称: Microtubule-associated protein tau
著者Falcon, B, Zivanov, J, Zhang, W, Murzin, A.G, Garringer, H.J, Vidal, R, Crowther, R.A, Newell, K.L, Ghetti, B, Goedert, M, Scheres, H.W.
登録日2019-02-07
公開日2019-03-27
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules.
Nature, 568, 2019
6NWQ
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Chronic traumatic encephalopathy Type II Tau filament
分子名称: Microtubule-associated protein tau
著者Falcon, B, Zivanov, J, Zhang, W, Murzin, A.G, Garringer, H.J, Vidal, R, Crowther, R.A, Newell, K.L, Ghetti, B, Goedert, M, Scheres, H.W.
登録日2019-02-07
公開日2019-03-27
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules.
Nature, 568, 2019
5O3O
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Pronase-treated paired helical filament in Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W.
登録日2017-05-24
公開日2017-07-26
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
5O3T
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Straight filament in Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W.
登録日2017-05-24
公開日2017-07-26
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
5O3L
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Paired helical filament in Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W.
登録日2017-05-24
公開日2017-07-26
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
1Z0R
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Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transcription-State Regulator AbrB
分子名称: Transition state regulatory protein abrB
著者Bobay, B.G, Andreeva, A, Mueller, G.A, Cavanagh, J, Murzin, A.G.
登録日2005-03-02
公開日2005-03-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Revised structure of the AbrB N-terminal domain unifies a diverse superfamily of putative DNA-binding proteins.
Febs Lett., 579, 2005
6HRE
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Paired helical filament from sporadic Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Falcon, B, Zhang, W, Schweighauser, M, Murzin, A.G, Vidal, R, Garringer, H.J, Ghetti, B, Scheres, S.H.W, Goedert, M.
登録日2018-09-26
公開日2018-10-10
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol., 136, 2018
6HRF
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Straight filament from sporadic Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Falcon, B, Zhang, W, Schweighauser, M, Murzin, A.G, Vidal, R, Garringer, H.J, Ghetti, B, Scheres, S.H.W, Goedert, M.
登録日2018-09-26
公開日2018-10-10
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol., 136, 2018
6GX5
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Narrow Pick Filament from Pick's disease brain
分子名称: Microtubule-associated protein tau
著者Falcon, B, Zhang, W, Murzin, A.G, Murshudov, G, Garringer, H.J, Vidal, R, Crowther, R.A, Ghetti, B, Scheres, S.H.W, Goedert, M.
登録日2018-06-26
公開日2018-09-12
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structures of filaments from Pick's disease reveal a novel tau protein fold.
Nature, 561, 2018
7NRV
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Paired helical filament from Alzheimer's disease with PET ligand APN-1607
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRQ
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Paired helical filament from primary age-related tauopathy brain
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRS
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Conformation 1 of straight filament from primary age-related tauopathy brain
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRT
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Conformation 2 of straight filament from primary age-related tauopathy brain
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRX
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BU of 7nrx by Molmil
Straight filament from Alzheimer's disease with PET ligand APN-1607
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
2W6L
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The crystal structure at 1.7 A resolution of CobE, a protein from the cobalamin (vitamin B12) biosynthetic pathway
分子名称: COBE, GLYCEROL, SULFATE ION
著者Vevodova, J, Smith, D, McGoldrick, H, Deery, E, Murzin, A.G, Warren, M.J, Wilson, K.S.
登録日2008-12-18
公開日2008-12-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献The Crystal Structure at 1.7 A Resolution of Cobe, a Protein from the Cobalamin (Vitamin B12) Biosynthetic Pathway
To be Published
1GUW
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STRUCTURE OF THE CHROMODOMAIN FROM MOUSE HP1beta IN COMPLEX WITH THE LYSINE 9-METHYL HISTONE H3 N-TERMINAL PEPTIDE, NMR, 25 STRUCTURES
分子名称: CHROMOBOX PROTEIN HOMOLOG 1, HISTONE H3.1
著者Nielsen, P.R, Nietlispach, D, Mott, H.R, Callaghan, J.M, Bannister, A, Kouzarides, T, Murzin, A.G, Murzina, N.V, Laue, E.D.
登録日2002-02-01
公開日2002-03-12
最終更新日2018-01-17
実験手法SOLUTION NMR
主引用文献Structure of the Hp1 Chromodomain Bound to Histone H3 Methylated at Lysine 9
Nature, 416, 2002
6XYO
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Multiple system atrophy Type I alpha-synuclein filament
分子名称: Alpha-synuclein
著者Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M.
登録日2020-01-30
公開日2020-02-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020
6XYP
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Multiple system atrophy Type II-1 alpha-synuclein filament
分子名称: Alpha-synuclein
著者Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M.
登録日2020-01-30
公開日2020-02-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020
6XYQ
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Multiple system atrophy Type II-2 alpha-synuclein filament
分子名称: Alpha-synuclein
著者Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M.
登録日2020-01-30
公開日2020-02-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020
1OI1
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Crystal Structure of the MBT domains of Human SCML2
分子名称: DI(HYDROXYETHYL)ETHER, SCML2 PROTEIN
著者Sathyamurthy, A, Allen, M.D, Murzin, A.G, Bycroft, M.
登録日2003-06-04
公開日2003-06-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal Structure of the Malignant Brain Tumor (Mbt) Repeats in Sex Comb on Midleg-Like 2 (Scml2).
J.Biol.Chem., 278, 2003
6TJO
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Cryo-EM structure of TypeI tau filaments extracted from the brains of individuals with Corticobasal degeneration
分子名称: Microtubule-associated protein tau
著者Zhang, W, Murzin, A.G, Falcon, B, Shi, Y, Goedert, M, Scheres, S.H.W.
登録日2019-11-26
公開日2020-02-05
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Novel tau filament fold in corticobasal degeneration.
Nature, 580, 2020

 

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