6LUE
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![BU of 6lue by Molmil](/molmil-images/mine/6lue) | Crystal structure of mouse Cryptochrome 1 in complex with compound KL201 | 分子名称: | 2-bromanyl-N-(5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)benzamide, Cryptochrome-1 | 著者 | Miller, S, Aikawa, Y, Hirota, T. | 登録日 | 2020-01-27 | 公開日 | 2020-06-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | An Isoform-Selective Modulator of Cryptochrome 1 Regulates Circadian Rhythms in Mammals. Cell Chem Biol, 27, 2020
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2X6I
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![BU of 2x6i by Molmil](/molmil-images/mine/2x6i) | THE CRYSTAL STRUCTURE OF THE DROSOPHILA CLASS III PI3-KINASE VPS34 IN COMPLEX WITH PIK-90 | 分子名称: | N-(2,3-DIHYDRO-7,8-DIMETHOXYIMIDAZO[1,2-C] QUINAZOLIN-5-YL)NICOTINAMIDE, PHOSPHOTIDYLINOSITOL 3 KINASE 59F | 著者 | Miller, S, Tavshanjian, B, Oleksy, A, Perisic, O, Houseman, B.T, Shokat, K.M, Williams, R.L. | 登録日 | 2010-02-17 | 公開日 | 2010-04-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34. Science, 327, 2010
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2X6H
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![BU of 2x6h by Molmil](/molmil-images/mine/2x6h) | THE CRYSTAL STRUCTURE OF THE DROSOPHILA CLASS III PI3-KINASE VPS34 | 分子名称: | PHOSPHOTIDYLINOSITOL 3 KINASE 59F | 著者 | Miller, S, Tavshanjian, B, Oleksy, A, Perisic, O, Houseman, B.T, Shokat, K.M, Williams, R.L. | 登録日 | 2010-02-17 | 公開日 | 2010-04-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34. Science, 327, 2010
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2X6K
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![BU of 2x6k by Molmil](/molmil-images/mine/2x6k) | THE CRYSTAL STRUCTURE OF THE DROSOPHILA CLASS III PI3-KINASE VPS34 IN COMPLEX WITH PI-103 | 分子名称: | 3-(4-MORPHOLIN-4-YLPYRIDO[3',2':4,5]FURO[3,2-D]PYRIMIDIN-2-YL)PHENOL, PHOSPHOTIDYLINOSITOL 3 KINASE 59F, SULFATE ION | 著者 | Miller, S, Tavshanjian, B, Oleksy, A, Perisic, O, Houseman, B.T, Shokat, K.M, Williams, R.L. | 登録日 | 2010-02-17 | 公開日 | 2010-04-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34. Science, 327, 2010
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2X6F
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![BU of 2x6f by Molmil](/molmil-images/mine/2x6f) | THE CRYSTAL STRUCTURE OF THE DROSOPHILA CLASS III PI3-KINASE VPS34 IN COMPLEX WITH 3-METHYLADENINE | 分子名称: | 6-AMINO-3-METHYLPURINE, PHOSPHOTIDYLINOSITOL 3 KINASE 59F | 著者 | Miller, S, Tavshanjian, B, Oleksy, A, Perisic, O, Houseman, B.T, Shokat, K.M, Williams, R.L. | 登録日 | 2010-02-17 | 公開日 | 2010-04-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34. Science, 327, 2010
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2X6J
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![BU of 2x6j by Molmil](/molmil-images/mine/2x6j) | THE CRYSTAL STRUCTURE OF THE DROSOPHILA CLASS III PI3-KINASE VPS34 IN COMPLEX WITH PIK-93 | 分子名称: | N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)- PHENYLTHIAZOLE-2-YL)-ACETAMIDE, PHOSPHOTIDYLINOSITOL 3 KINASE 59F | 著者 | Miller, S, Tavshanjian, B, Oleksy, A, Perisic, O, Houseman, B.T, Shokat, K.M, Williams, R.L. | 登録日 | 2010-02-17 | 公開日 | 2010-04-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34. Science, 327, 2010
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2XI2
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![BU of 2xi2 by Molmil](/molmil-images/mine/2xi2) | HCV-H77 NS5B Apo Polymerase | 分子名称: | RNA-directed RNA polymerase, SULFATE ION | 著者 | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | 登録日 | 2010-06-25 | 公開日 | 2010-08-04 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis J.Biol.Chem., 285, 2010
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2XHV
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![BU of 2xhv by Molmil](/molmil-images/mine/2xhv) | HCV-J4 NS5B Polymerase Point Mutant Orthorhombic Crystal Form | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase, SULFATE ION | 著者 | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | 登録日 | 2010-06-21 | 公開日 | 2010-08-04 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis J.Biol.Chem., 285, 2010
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2XHW
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![BU of 2xhw by Molmil](/molmil-images/mine/2xhw) | HCV-J4 NS5B Polymerase Trigonal Crystal Form | 分子名称: | RNA-directed RNA polymerase | 著者 | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | 登録日 | 2010-06-21 | 公開日 | 2010-08-04 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis J.Biol.Chem., 285, 2010
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2YBD
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![BU of 2ybd by Molmil](/molmil-images/mine/2ybd) | Crystal structure of probable had family hydrolase from pseudomonas fluorescens pf-5 with bound phosphate | 分子名称: | HYDROLASE, HALOACID DEHALOGENASE-LIKE FAMILY, MAGNESIUM ION, ... | 著者 | Vetting, M.W, Patskovsky, Y, Toro, R, Freeman, J, Miller, S, Sauder, J.M, Burley, S.K, Dunaway-Mariano, D, Allen, K.N, Gerlt, J.A, Almo, S.C. | 登録日 | 2011-03-03 | 公開日 | 2011-03-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Crystal Structure of Probable Had Family Hydrolase from Pseudomonas Fluorescens Pf-5 with Bound Phosphate To be Published
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8E7X
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![BU of 8e7x by Molmil](/molmil-images/mine/8e7x) | RsTSPO A138F with one Heme bound | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PROTOPORPHYRIN IX CONTAINING FE, Tryptophan-rich sensory protein | 著者 | Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S. | 登録日 | 2022-08-25 | 公開日 | 2023-03-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity. Biochemistry, 62, 2023
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8E7Y
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![BU of 8e7y by Molmil](/molmil-images/mine/8e7y) | RsTSPO A138F with two heme bound | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PROTOPORPHYRIN IX CONTAINING FE, Tryptophan-rich sensory protein | 著者 | Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S. | 登録日 | 2022-08-25 | 公開日 | 2023-03-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity. Biochemistry, 62, 2023
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8E7Z
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![BU of 8e7z by Molmil](/molmil-images/mine/8e7z) | RsTSPO mutant -A138F | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Tryptophan-rich sensory protein | 著者 | Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S. | 登録日 | 2022-08-25 | 公開日 | 2023-03-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity. Biochemistry, 62, 2023
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8E7W
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![BU of 8e7w by Molmil](/molmil-images/mine/8e7w) | RsTSPO A139T with Heme | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S. | 登録日 | 2022-08-25 | 公開日 | 2023-03-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity. Biochemistry, 62, 2023
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8E7B
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![BU of 8e7b by Molmil](/molmil-images/mine/8e7b) | Crystal structure of the p53 (Y107H) core domain monoclinic P form | 分子名称: | Cellular tumor antigen p53, ZINC ION | 著者 | Lovell, S, Liu, L, Battaile, K.P, Miller, S, Karanicolas, J. | 登録日 | 2022-08-23 | 公開日 | 2023-05-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression. Cancer Discov, 13, 2023
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8E7A
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![BU of 8e7a by Molmil](/molmil-images/mine/8e7a) | Crystal structure of the p53 (Y107H) core domain orthorhombic P form | 分子名称: | Cellular tumor antigen p53, ZINC ION | 著者 | Lovell, S, Liu, L, Battaile, K.P, Miller, S, Karanicolas, J. | 登録日 | 2022-08-23 | 公開日 | 2023-05-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression. Cancer Discov, 13, 2023
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4UC1
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![BU of 4uc1 by Molmil](/molmil-images/mine/4uc1) | High resolution crystal structure of translocator protein 18kDa (TSPO) from Rhodobacter sphaeroides (A139T Mutant) in C2 space group | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-1-(hexadecanoyloxy)-3-hydroxypropan-2-yl (11Z)-octadec-11-enoate, METHOXY-ETHOXYL, ... | 著者 | Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S. | 登録日 | 2014-08-13 | 公開日 | 2015-02-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism. Science, 347, 2015
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4UC3
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![BU of 4uc3 by Molmil](/molmil-images/mine/4uc3) | Translocator protein 18 kDa (TSPO) from Rhodobacter sphaeroides wild type | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, TRANSLOCATOR PROTEIN TSPO | 著者 | Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S. | 登録日 | 2014-08-13 | 公開日 | 2015-02-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism. Science, 347, 2015
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4UC2
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![BU of 4uc2 by Molmil](/molmil-images/mine/4uc2) | Crystal structure of translocator protein 18kDa (TSPO) from rhodobacter sphaeroides (A139T mutant) in P212121 space group | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, TETRAETHYLENE GLYCOL, TRANSLOCATOR PROTEIN TSPO | 著者 | Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S. | 登録日 | 2014-08-13 | 公開日 | 2015-02-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism. Science, 347, 2015
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5DUO
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![BU of 5duo by Molmil](/molmil-images/mine/5duo) | Crystal structure of native translocator protein 18kDa (TSPO) from Rhodobacter sphaeroides (A139T Mutant) in C2 space group | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, FORMIC ACID, PROTOPORPHYRIN IX, ... | 著者 | Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S. | 登録日 | 2015-09-20 | 公開日 | 2015-11-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Response to Comment on "Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism". Science, 350, 2015
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3SZ9
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![BU of 3sz9 by Molmil](/molmil-images/mine/3sz9) | |
6PW1
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![BU of 6pw1 by Molmil](/molmil-images/mine/6pw1) | Cytochrome c Oxidase delta 16 | 分子名称: | (2S,3R)-heptane-1,2,3-triol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, ... | 著者 | Liu, J, Ferguson-Miller, S. | 登録日 | 2019-07-21 | 公開日 | 2019-11-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural changes at the surface of cytochrome c oxidase alter the proton-pumping stoichiometry. Biochim Biophys Acta Bioenerg, 1861, 2019
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6PW0
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![BU of 6pw0 by Molmil](/molmil-images/mine/6pw0) | Cytochrome C oxidase delta 6 mutant | 分子名称: | (2S,3R)-heptane-1,2,3-triol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, ... | 著者 | Liu, J, Ferguson-Miller, S. | 登録日 | 2019-07-21 | 公開日 | 2019-11-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural changes at the surface of cytochrome c oxidase alter the proton-pumping stoichiometry. Biochim Biophys Acta Bioenerg, 1861, 2019
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1O05
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![BU of 1o05 by Molmil](/molmil-images/mine/1o05) | |
2GSM
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![BU of 2gsm by Molmil](/molmil-images/mine/2gsm) | Catalytic Core (Subunits I and II) of Cytochrome c oxidase from Rhodobacter sphaeroides | 分子名称: | CADMIUM ION, CALCIUM ION, COPPER (II) ION, ... | 著者 | Qin, L, Hiser, C, Mulichak, A, Garavito, R.M, Ferguson-Miller, S. | 登録日 | 2006-04-26 | 公開日 | 2006-10-10 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Identification of conserved lipid/detergent-binding sites in a high-resolution structure of the membrane protein cytochrome c oxidase. Proc.Natl.Acad.Sci.Usa, 103, 2006
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