8E7A

Crystal structure of the p53 (Y107H) core domain orthorhombic P form

Summary for 8E7A

• Entry DOI: 10.2210/pdb8e7a/pdb
• Descriptor: Cellular tumor antigen p53, ZINC ION (3 entities in total)
• Functional Keywords: dna binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 24758.46

Authors

Lovell, S.,Liu, L.,Battaile, K.P.,Miller, S.,Karanicolas, J. (deposition date: 2022-08-23, release date: 2023-05-17, Last modification date: 2023-10-25)

• Primary citation: Indeglia, A.,Leung, J.C.,Miller, S.A.,Leu, J.I.,Dougherty, J.F.,Clarke, N.L.,Kirven, N.A.,Shao, C.,Ke, L.,Lovell, S.,Barnoud, T.,Lu, D.Y.,Lin, C.,Kannan, T.,Battaile, K.P.,Yang, T.H.L.,Batista Oliva, I.,Claiborne, D.T.,Vogel, P.,Liu, L.,Liu, Q.,Nefedova, Y.,Cassel, J.,Auslander, N.,Kossenkov, A.V.,Karanicolas, J.,Murphy, M.E.; An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression.; Cancer Discov, 13:1696-1719, 2023; PubMed: 37140445; DOI: 10.1158/2159-8290.CD-22-1315

Experimental method

X-RAY DIFFRACTION (1.3 Å)