8VKE
| |
8VIF
| |
8VWW
| CCHFV GP38 bound to ADI-46152 and ADI-58048 Fabs | Descriptor: | ADI-46152 Fab Heavy Chain, ADI-46152 Fab Light Chain, ADI-58048 Fab Heavy Chain, ... | Authors: | Hjorth, C.K, McLellan, J.S. | Deposit date: | 2024-02-02 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38. Cell Rep, 43, 2024
|
|
8VVK
| CCHFV GP38 bound to ADI-46143 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-46143 Fab Heavy Chain, ADI-46143 Fab Light Chain, ... | Authors: | Hjorth, C.K, McLellan, J.S. | Deposit date: | 2024-01-31 | Release date: | 2024-07-17 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38. Cell Rep, 43, 2024
|
|
8VVL
| CCHFV GP38 bound to c13G8 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Hjorth, C.K, Mishra, A.K, McLellan, J.S. | Deposit date: | 2024-01-31 | Release date: | 2024-07-17 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38. Cell Rep, 43, 2024
|
|
8DMJ
| |
8DNG
| |
8DNR
| |
8DO4
| |
8FU3
| Structure Of Respiratory Syncytial Virus Polymerase with Novel Non-Nucleoside Inhibitor | Descriptor: | 8-methoxy-3-methyl-N-{(2S)-3,3,3-trifluoro-2-[5-fluoro-6-(4-fluorophenyl)-4-(2-hydroxypropan-2-yl)pyridin-2-yl]-2-hydroxypropyl}cinnoline-6-carboxamide, Phosphoprotein, RNA-directed RNA polymerase L | Authors: | Yu, X, Abeywickrema, P, Bonneux, B, Behera, I, Jacoby, E, Fung, A, Adhikary, S, Bhaumik, A, Carbajo, R.J, Bruyn, S.D, Miller, R, Patrick, A, Pham, Q, Piassek, M, Verheyen, N, Shareef, A, Sutto-Ortiz, P, Ysebaert, N, Vlijmen, H.V, Jonckers, T.H.M, Herschke, F, McLellan, J.S, Decroly, E, Fearns, R, Grosse, S, Roymans, D, Sharma, S, Rigaux, P, Jin, Z. | Deposit date: | 2023-01-16 | Release date: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Structural and mechanistic insights into the inhibition of respiratory syncytial virus polymerase by a non-nucleoside inhibitor. Commun Biol, 6, 2023
|
|
7S3N
| |
7SJ0
| |
7T01
| SARS-CoV-2 S-RBD + Fab 54042-4 | Descriptor: | 54042-4 Fab - Heavy Chain, 54042-4 Fab - Light Chain, Spike protein S1 | Authors: | Johnson, N.V, Mclellan, J.S. | Deposit date: | 2021-11-29 | Release date: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognition. Cell Rep, 37, 2021
|
|
7T67
| SARS-CoV-2 S (Spike Glycoprotein) D614G with One(1) RBD Up | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Byrne, P.O, McLellan, J.S. | Deposit date: | 2021-12-13 | Release date: | 2022-08-24 | Last modified: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern. Nat Commun, 13, 2022
|
|
7T3M
| SARS-CoV-2 S (Spike Glycoprotein) D614G with Three (3) RBDs Up, Bound to Antibody 2-7 scFv, composite map | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2-7 scFv, ... | Authors: | Byrne, P.O, McLellan, J.S. | Deposit date: | 2021-12-08 | Release date: | 2022-08-24 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern. Nat Commun, 13, 2022
|
|
7SSC
| |
7SEM
| Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ... | Authors: | Rush, S.A, Hsieh, C.-L, McLellan, J.S. | Deposit date: | 2021-09-30 | Release date: | 2022-02-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins. Nat Commun, 13, 2022
|
|
7TJQ
| SAN27-14 bound to a antigenic site V on prefusion-stabilized hMPV F | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ... | Authors: | Hsieh, C.-L, McLellan, J.S, Rush, S.A. | Deposit date: | 2022-01-16 | Release date: | 2022-09-14 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus. Cell Rep, 40, 2022
|
|
7TL0
| Cryo-EM structure of hMPV preF bound by Fabs MPE8 and SAN32-2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ... | Authors: | Rush, S.A, Hsieh, C.-L, McLellan, J.S. | Deposit date: | 2022-01-17 | Release date: | 2022-09-14 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus. Cell Rep, 40, 2022
|
|
7SEJ
| |
6EAH
| |
6EAL
| |
6EAM
| |
6EAD
| |
6EAF
| |