Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 183 件
5UDC
DownloadVisualize
BU of 5udc by Molmil
Crystal Structure of RSV F A2 Bound to MEDI8897
分子名称: CHLORIDE ION, Fusion glycoprotein F0, MEDI8897 Fab Heavy Chain, ...
著者McLellan, J.S.
登録日2016-12-26
公開日2017-05-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants.
Sci Transl Med, 9, 2017
5UDD
DownloadVisualize
BU of 5udd by Molmil
Crystal Structure of RSV F B9320 Bound to MEDI8897
分子名称: Fusion glycoprotein F0, MEDI8897 Fab Heavy Chain, MEDI8897 Fab Light Chain, ...
著者McLellan, J.S.
登録日2016-12-26
公開日2017-05-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants.
Sci Transl Med, 9, 2017
4JHA
DownloadVisualize
BU of 4jha by Molmil
Crystal Structure of RSV-Neutralizing Human Antibody D25
分子名称: D25 antigen-binding fragment heavy chain, D25 light chain
著者Mclellan, J.S, Chen, M, Leung, S, Graepel, K.W, Du, X, Yang, Y, Zhou, T, Baxa, U, Yasuda, E, Beaumont, T, Kumar, A, Modjarrad, K, Zheng, Z, Zhao, M, Xia, N, Kwong, P.D, Graham, B.S.
登録日2013-03-04
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Science, 340, 2013
4MMS
DownloadVisualize
BU of 4mms by Molmil
Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 5.5
分子名称: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, SULFATE ION
著者Mclellan, J.S, Joyce, M.G, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D.
登録日2013-09-09
公開日2013-11-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.397 Å)
主引用文献Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMQ
DownloadVisualize
BU of 4mmq by Molmil
Crystal Structure of Prefusion-stabilized RSV F Variant DS
分子名称: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, SULFATE ION
著者Mclellan, J.S, Joyce, M.G, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D.
登録日2013-09-09
公開日2013-11-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.253 Å)
主引用文献Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4JHW
DownloadVisualize
BU of 4jhw by Molmil
Crystal Structure of Respiratory Syncytial Virus Fusion Glycoprotein Stabilized in the Prefusion Conformation by Human Antibody D25
分子名称: D25 antigen-binding fragment heavy chain, D25 light chain, Fusion glycoprotein F0
著者Mclellan, J.S, Chen, M, Leung, S, Graepel, K.W, Du, X, Yang, Y, Zhou, T, Baxa, U, Yasuda, E, Beaumont, T, Kumar, A, Modjarrad, K, Zheng, Z, Zhao, M, Xia, N, Kwong, P.D, Graham, B.S.
登録日2013-03-05
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Science, 340, 2013
7RAH
DownloadVisualize
BU of 7rah by Molmil
Adenylate cyclase toxin RTX domain fragment bound to M1H5 Fab and M2B10 Fab
分子名称: Bifunctional adenylate cyclase toxin/hemolysin CyaA,Bifunctional adenylate cyclase toxin/hemolysin CyaA, CALCIUM ION, M1H5 Fab Heavy Chain, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2021-07-01
公開日2021-09-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for antibody binding to adenylate cyclase toxin reveals RTX linkers as neutralization-sensitive epitopes.
Plos Pathog., 17, 2021
5I08
DownloadVisualize
BU of 5i08 by Molmil
Prefusion structure of a human coronavirus spike protein
分子名称: Spike glycoprotein,Foldon chimera
著者Kirchdoerfer, R.N, Cottrell, C.A, Wang, N, Pallesen, J, Yassine, H.M, Turner, H.L, Corbett, K.S, Graham, B.S, McLellan, J.S, Ward, A.B.
登録日2016-02-03
公開日2016-03-02
最終更新日2020-04-22
実験手法ELECTRON MICROSCOPY (4.04 Å)
主引用文献Pre-fusion structure of a human coronavirus spike protein.
Nature, 531, 2016
6XKL
DownloadVisualize
BU of 6xkl by Molmil
SARS-CoV-2 HexaPro S One RBD up
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Wrapp, D, Hsieh, C.-L, Goldsmith, J.A, McLellan, J.S.
登録日2020-06-26
公開日2020-07-15
最終更新日2020-09-30
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Structure-based design of prefusion-stabilized SARS-CoV-2 spikes.
Science, 369, 2020
5W24
DownloadVisualize
BU of 5w24 by Molmil
Crystal Structure of 5C4 Fab
分子名称: (R,R)-2,3-BUTANEDIOL, 5C4 Fab Heavy Chain, 5C4 Fab Light Chain
著者Battles, M.B, McLellan, J.S, Taher, N.M.
登録日2017-06-05
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein.
Nat Commun, 8, 2017
5L1X
DownloadVisualize
BU of 5l1x by Molmil
Structure of the Human Metapneumovirus Fusion Protein in the Postfusion Conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Mas, V, Melero, J.A, McLellan, J.S.
登録日2016-07-29
公開日2016-08-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Engineering, Structure and Immunogenicity of the Human Metapneumovirus F Protein in the Postfusion Conformation.
Plos Pathog., 12, 2016
3TCL
DownloadVisualize
BU of 3tcl by Molmil
Crystal Structure of HIV-1 Neutralizing Antibody CH04
分子名称: CH04 Heavy Chain Fab, CH04 Light Chain Fab, IMIDAZOLE
著者Louder, R.K, McLellan, J.S, Pancera, M, Yang, Y, Zhang, B, Bonsignori, M, Kwong, P.D.
登録日2011-08-09
公開日2011-11-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.906 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
8VCR
DownloadVisualize
BU of 8vcr by Molmil
SARS-CoV-2 Spike S2 bound to Fab 54043-5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 54043-5 Fab Heavy Chain, ...
著者Johnson, N.V, McLellan, J.S.
登録日2023-12-14
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Discovery and Characterization of a Pan-betacoronavirus S2-binding antibody
To Be Published
4ZYK
DownloadVisualize
BU of 4zyk by Molmil
Crystal Structure of Quaternary-Specific RSV-Neutralizing Human Antibody AM14
分子名称: 1,2-ETHANEDIOL, ACETATE ION, AM14 Fab heavy chain, ...
著者Gilman, M.S.A, McLellan, J.S.
登録日2015-05-21
公開日2015-07-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein.
Plos Pathog., 11, 2015
8SAK
DownloadVisualize
BU of 8sak by Molmil
BtCoV-422 in complex with neutralizing antibody JC57-11
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者McFadden, E, McLellan, J.S.
登録日2023-04-01
公開日2023-10-04
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus.
Sci Transl Med, 15, 2023
7M8J
DownloadVisualize
BU of 7m8j by Molmil
SARS-CoV-2 S-NTD + Fab CM25
分子名称: CM25 Fab - Heavy Chain, CM25 Fab - Light Chain, Spike protein S1
著者Johnson, N.V, Mclellan, J.S.
登録日2021-03-29
公開日2021-05-19
最終更新日2021-06-16
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes.
Science, 372, 2021
7M30
DownloadVisualize
BU of 7m30 by Molmil
Cryo-EM structure of the HCMV pentamer bound by antibodies 1-103, 1-32 and 2-25
分子名称: 1-103 Fab Heavy Chain, 1-103 Fab Light Chain, 1-32 Fab Heavy Chain, ...
著者Wrapp, D, McLellan, J.S.
登録日2021-03-17
公開日2021-08-11
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
5W23
DownloadVisualize
BU of 5w23 by Molmil
Crystal Structure of RSV F in complex with 5C4 Fab
分子名称: 5C4 Fab heavy chain, 5C4 Fab light chain, Fusion glycoprotein F0, ...
著者Battles, M.B, McLellan, J.S.
登録日2017-06-05
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein.
Nat Commun, 8, 2017
5VYH
DownloadVisualize
BU of 5vyh by Molmil
Crystal Structure of MERS-CoV S1 N-terminal Domain
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ...
著者Wang, N, Wrapp, D, Pallesen, J, Ward, A.B, McLellan, J.S.
登録日2017-05-25
公開日2017-08-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4DQO
DownloadVisualize
BU of 4dqo by Molmil
Crystal Structure of PG16 Fab in Complex with V1V2 Region from HIV-1 strain ZM109
分子名称: 1FD6-V1V2 scaffold ZM109 HIV-1 strain, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PG16 Fab Heavy Chain, ...
著者Pancera, M, McLellan, J.S, Kwong, P.D.
登録日2012-02-16
公開日2013-03-06
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.438 Å)
主引用文献Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16.
Nat.Struct.Mol.Biol., 20, 2013
6DC3
DownloadVisualize
BU of 6dc3 by Molmil
RSV prefusion F bound to RSD5 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab RSD5-Germline Heavy Chain, Fab RSD5-Germline Light Chain, ...
著者Battles, M.B, McLellan, J.S, Jones, H.J.
登録日2018-05-04
公開日2019-07-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.501 Å)
主引用文献Alternative conformations of a major antigenic site on RSV F.
Plos Pathog., 15, 2019
6DC5
DownloadVisualize
BU of 6dc5 by Molmil
RSV prefusion F in complex with AM22 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Jones, H.G, McLellan, J.S.
登録日2018-05-04
公開日2019-07-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Alternative conformations of a major antigenic site on RSV F.
Plos Pathog., 15, 2019
6EAG
DownloadVisualize
BU of 6eag by Molmil
CRYSTAL STRUCTURE OF FUSION INHIBITOR JNJ-2408068 IN COMPLEX WITH HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN ESCAPE VARIANT G143S STABILIZED IN THE PREFUSION STATE
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-[[2-[[1-(2-azanylethyl)piperidin-4-yl]amino]-4-methyl-benzimidazol-1-yl]methyl]-6-methyl-pyridin-3-ol, D(-)-TARTARIC ACID, ...
著者Battles, M.B, McLellan, J.S.
登録日2018-08-03
公開日2019-08-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.302 Å)
主引用文献Structural Basis for Respiratory Syncytial Virus Fusion Inhibitor Resistance
To be published
6EAN
DownloadVisualize
BU of 6ean by Molmil
CRYSTAL STRUCTURE OF HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN INHIBITOR ESCAPE VARIANT F488I STABILIZED IN THE PREFUSION STATE
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ...
著者Battles, M.B, McLellan, J.S.
登録日2018-08-03
公開日2019-08-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural Basis for Respiratory Syncytial Virus Fusion Inhibitor Resistance
To be published
8VAO
DownloadVisualize
BU of 8vao by Molmil
Simulation-driven design of prefusion stabilized SARS-CoV-2 spike S2 antigen
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
著者Zhou, L, McLellan, J.S.
登録日2023-12-11
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Simulation-Driven Design of Stabilized SARS-CoV-2 Spike S2 Immunogens
To Be Published

223166

件を2024-07-31に公開中

PDB statisticsPDBj update infoContact PDBjnumon