8SAK

BtCoV-422 in complex with neutralizing antibody JC57-11

Summary for 8SAK

• Entry DOI: 10.2210/pdb8sak/pdb
• EMDB information: 40272 40306 40310
• Descriptor: Spike glycoprotein, JC57-11 Fab heavy chain, JC57-11 Fab light chain, ... (7 entities in total)
• Functional Keywords: coronavirus, mers, neutralizing, antibody, mers-like, merbecovirus, bat, virus, cdrh3, rbd, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Middle East respiratory syndrome-related coronavirus; More
• Total number of polymer chains: 5
• Total formula weight: 463431.62

Authors

McFadden, E.,McLellan, J.S. (deposition date: 2023-04-01, release date: 2023-10-04)

• Primary citation: Tse, L.V.,Hou, Y.J.,McFadden, E.,Lee, R.E.,Scobey, T.D.,Leist, S.R.,Martinez, D.R.,Meganck, R.M.,Schafer, A.,Yount, B.L.,Mascenik, T.,Powers, J.M.,Randell, S.H.,Zhang, Y.,Wang, L.,Mascola, J.,McLellan, J.S.,Baric, R.S.; A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus.; Sci Transl Med, 15:eadg5567-eadg5567, 2023; PubMed: 37756379; DOI: 10.1126/scitranslmed.adg5567

Experimental method

ELECTRON MICROSCOPY (3 Å)