8SAK
BtCoV-422 in complex with neutralizing antibody JC57-11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Spike glycoprotein | polymer | 1289 | 142101.1 | 3 | UniProt (A0A2R4KP93) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | unclassified Merbecovirus | S glycoprotein,E2,Peplomer protein |
| 2 | H | JC57-11 Fab heavy chain | polymer | 237 | 25037.1 | 1 | Macaca | ||
| 3 | L | JC57-11 Fab light chain | polymer | 216 | 23264.7 | 1 | Macaca | ||
| 4 | E, K, U, X, c... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 12 | In PDB GlyTouCan (G42666HT) | |||
| 5 | Q, h, 1 | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 3 | In PDB GlyTouCan (G21290RB) | |||
| 6 | t | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 7 | A, B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 18 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 1289 (UniProt: A0A2R4KP93)
| PDB | External Database | Details |
|---|---|---|
| Pro 885 | Ala 885 | engineered mutation |
| Pro 1056 | Ala 1056 | engineered mutation |
| Pro 1057 | Val 1057 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 474605.1 | |
| Branched | Number of molecules | 16 |
| Total formula weight | 7715.3 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3981.7 | |
| All* | Total formula weight | 486302.1 |
