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PDB: 188 results
7LUE
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BU of 7lue by Molmil
Prefusion RSV F glycoprotein bound by neutralizing site V-directed antibody ADI-14442
Descriptor: Fusion glycoprotein F0, Heavy chain of human antibody Fab ADI-14442, Light chain of human antibody Fab ADI-14442
Authors:Gilman, M.S.A, McLellan, J.S.
Deposit date:2021-02-22
Release date:2021-06-16
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.
Immunity, 54, 2021
7LUD
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BU of 7lud by Molmil
Crystal structure of Fab ADI-14442
Descriptor: ADI-14442 Fab Heavy chain, ADI-14442 Fab Light chain, SULFATE ION
Authors:Rush, S.A, McLellan, J.S.
Deposit date:2021-02-22
Release date:2021-06-16
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.
Immunity, 54, 2021
7KX4
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BU of 7kx4 by Molmil
Anti-CCHFV ADI-36121 Fab
Descriptor: ADI-36121 Fab heavy chain, ADI-36121 Fab light chain
Authors:Mishra, A.K, McLellan, J.S.
Deposit date:2020-12-03
Release date:2021-12-01
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.
Science, 375, 2022
7LVW
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BU of 7lvw by Molmil
Structure of RSV F in Complex with VHH Cl184
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, F-VHH-Cl184, ...
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2021-02-26
Release date:2021-03-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A vulnerable, membrane-proximal site in human respiratory syncytial virus F revealed by a prefusion-specific single-domain antibody.
J.Virol., 95, 2021
7LVU
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BU of 7lvu by Molmil
Structure of RSV F-directed VHH Cl184
Descriptor: F-VHH-Cl184
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2021-02-26
Release date:2021-03-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:A vulnerable, membrane-proximal site in human respiratory syncytial virus F revealed by a prefusion-specific single-domain antibody.
J.Virol., 95, 2021
7KBB
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BU of 7kbb by Molmil
Cryo-EM structure of the HCMV pentamer bound by Fabs 2-18 and 8I21
Descriptor: 2-18 Fab Heavy Chain, 2-18 Fab Light Chain, 8I21 Fab Heavy Chain, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2020-10-01
Release date:2021-08-11
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7KBA
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BU of 7kba by Molmil
Crystal structure of the HCMV pentamer-specific Fab 2-18
Descriptor: 2-18 Fab Heavy Chain, 2-18 Fab Light Chain
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2020-10-01
Release date:2021-08-11
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7LYV
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BU of 7lyv by Molmil
Crystal structure of the HCMV pentamer-specific antibody 1-103
Descriptor: 1-103 Fab Heavy Chain, 1-103 Fab Light Chain
Authors:Wrapp, D, Jones, H.G, McLellan, J.S.
Deposit date:2021-03-08
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7LYW
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BU of 7lyw by Molmil
Crystal structure of the HCMV pentamer-specific antibody 2-25
Descriptor: 2-25 Fab Heavy Chain, 2-25 Fab Light Chain
Authors:Wrapp, D, Mishra, A.K, McLellan, J.S.
Deposit date:2021-03-08
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
6BLI
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BU of 6bli by Molmil
RSV G peptide bound to Fab CB002.5
Descriptor: CB002.5 Fab Heavy Chain, CB002.5 Fab Light Chain, Major surface glycoprotein G
Authors:Jones, H.G, McLellan, J.S, Langedijk, J.P.
Deposit date:2017-11-10
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.
PLoS Pathog., 14, 2018
6C6Z
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BU of 6c6z by Molmil
Crystal structure of potent neutralizing antibody CDC2-C2 in complex with MERS-CoV S1 RBD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CDC2-C2 heavy chain, Antibody CDC2-C2 light chain, ...
Authors:Wang, N, McLellan, J.S.
Deposit date:2018-01-19
Release date:2018-01-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape.
J. Virol., 92, 2018
6BLH
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BU of 6blh by Molmil
RSV G central conserved region bound to Fab CB017.5
Descriptor: 1,2-ETHANEDIOL, Fab CB017.5 heavy chain, Fab CB017.5 light chain, ...
Authors:Jones, H.G, McLellan, J.S, Langedijk, J.P.
Deposit date:2017-11-10
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.
PLoS Pathog., 14, 2018
6CRZ
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BU of 6crz by Molmil
SARS Spike Glycoprotein, Trypsin-cleaved, Stabilized variant, C3 symmetry
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ...
Authors:Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CS2
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BU of 6cs2 by Molmil
SARS Spike Glycoprotein - human ACE2 complex, Stabilized variant, all ACE2-bound particles
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CS1
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BU of 6cs1 by Molmil
SARS Spike Glycoprotein, Trypsin-cleaved, Stabilized variant, two S1 CTDs in an upwards conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ...
Authors:Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRX
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BU of 6crx by Molmil
SARS Spike Glycoprotein, Stabilized variant, two S1 CTDs in the upwards conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ...
Authors:Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRW
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BU of 6crw by Molmil
SARS Spike Glycoprotein, Stabilized variant, single upwards S1 CTD conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ...
Authors:Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRV
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BU of 6crv by Molmil
SARS Spike Glycoprotein, Stabilized variant, C3 symmetry
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ...
Authors:Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CS0
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BU of 6cs0 by Molmil
SARS Spike Glycoprotein, Trypsin-cleaved, Stabilized variant, one S1 CTD in an upwards conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ...
Authors:Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6DC3
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BU of 6dc3 by Molmil
RSV prefusion F bound to RSD5 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab RSD5-Germline Heavy Chain, Fab RSD5-Germline Light Chain, ...
Authors:Battles, M.B, McLellan, J.S, Jones, H.J.
Deposit date:2018-05-04
Release date:2019-07-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.501 Å)
Cite:Alternative conformations of a major antigenic site on RSV F.
Plos Pathog., 15, 2019
6DC4
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BU of 6dc4 by Molmil
RSV-neutralizing human antibody AM22
Descriptor: 1,2-ETHANEDIOL, Fab AM22 Heavy Chain, Fab AM22 Light Chain
Authors:Jones, H.G, McLellan, J.S.
Deposit date:2018-05-04
Release date:2019-07-10
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Alternative conformations of a major antigenic site on RSV F.
Plos Pathog., 15, 2019
6DC5
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BU of 6dc5 by Molmil
RSV prefusion F in complex with AM22 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Jones, H.G, McLellan, J.S.
Deposit date:2018-05-04
Release date:2019-07-10
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Alternative conformations of a major antigenic site on RSV F.
Plos Pathog., 15, 2019
6EAG
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BU of 6eag by Molmil
CRYSTAL STRUCTURE OF FUSION INHIBITOR JNJ-2408068 IN COMPLEX WITH HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN ESCAPE VARIANT G143S STABILIZED IN THE PREFUSION STATE
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-[[2-[[1-(2-azanylethyl)piperidin-4-yl]amino]-4-methyl-benzimidazol-1-yl]methyl]-6-methyl-pyridin-3-ol, D(-)-TARTARIC ACID, ...
Authors:Battles, M.B, McLellan, J.S.
Deposit date:2018-08-03
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.302 Å)
Cite:Structural Basis for Respiratory Syncytial Virus Fusion Inhibitor Resistance
To be published
6EAN
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BU of 6ean by Molmil
CRYSTAL STRUCTURE OF HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN INHIBITOR ESCAPE VARIANT F488I STABILIZED IN THE PREFUSION STATE
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ...
Authors:Battles, M.B, McLellan, J.S.
Deposit date:2018-08-03
Release date:2019-08-07
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for Respiratory Syncytial Virus Fusion Inhibitor Resistance
To be published
3ONU
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BU of 3onu by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026
Descriptor: 1,2-ETHANEDIOL, Capsid protein
Authors:Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
Deposit date:2010-08-30
Release date:2011-05-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.395 Å)
Cite:Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability.
J.Virol., 85, 2011

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