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PDB: 183 件
8DNG
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BU of 8dng by Molmil
Prefusion-stabilized Nipah virus fusion protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
著者Byrne, P.O, Blade, E.G, McLellan, J.S.
登録日2022-07-11
公開日2023-07-19
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Prefusion stabilization of the Hendra and Langya virus F proteins.
J.Virol., 98, 2024
8DNR
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BU of 8dnr by Molmil
Prefusion-stabilized Hendra virus fusion protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
著者Byrne, P.O, Blade, E.G, McLellan, J.S.
登録日2022-07-11
公開日2023-07-19
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Prefusion stabilization of the Hendra and Langya virus F proteins.
J.Virol., 98, 2024
8DO4
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BU of 8do4 by Molmil
Prefusion-stabilized Nipah virus fusion protein, dimer of trimers
分子名称: Fusion glycoprotein F0
著者Byrne, P.O, Blade, E.G, McLellan, J.S.
登録日2022-07-12
公開日2023-07-19
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Prefusion stabilization of the Hendra and Langya virus F proteins.
J.Virol., 98, 2024
8SAK
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BU of 8sak by Molmil
BtCoV-422 in complex with neutralizing antibody JC57-11
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者McFadden, E, McLellan, J.S.
登録日2023-04-01
公開日2023-10-04
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus.
Sci Transl Med, 15, 2023
8T7A
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BU of 8t7a by Molmil
Cryo-EM structure of RSV preF in complex with Fab 2.4K
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2.4K Fab Heavy Chain, 2.4K Fab Light Chain, ...
著者McCool, R.S, McLellan, J.S.
登録日2023-06-20
公開日2023-09-13
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein elicits antibodies targeting a membrane-proximal epitope.
J.Virol., 97, 2023
8TMA
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BU of 8tma by Molmil
Antibody N3-1 bound to RBD in the up conformation
分子名称: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein
著者Hsieh, C.-L, McLellan, J.S.
登録日2023-07-29
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Commun Biol, 6, 2023
8TM1
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BU of 8tm1 by Molmil
Antibody N3-1 bound to RBDs in the up and down conformations
分子名称: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein
著者Hsieh, C.-L, McLellan, J.S.
登録日2023-07-27
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Commun Biol, 6, 2023
8TW3
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BU of 8tw3 by Molmil
hMPV fusion protein complexed with single domain antibodies sdHMPV16 and sdHMPV12
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein, Single domain antibody sdHMPV12, ...
著者Rush, S.A, McLellan, J.S.
登録日2023-08-19
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A neutralizing single-domain antibody that targets the trimer interface of the human metapneumovirus fusion protein.
Mbio, 15, 2024
8V5K
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BU of 8v5k by Molmil
Structure of the Human Respirovirus 3 Fusion Protein Bound to Camelid Nanobodies 4C03 and 4C06
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Camelid Nanobody 4C03, Camelid Nanobody 4C06, ...
著者Johnson, N.V, Ramamohan, A.R, McLellan, J.S.
登録日2023-11-30
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis for potent neutralization of human respirovirus type 3 by protective single-domain camelid antibodies.
Nat Commun, 15, 2024
8V62
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BU of 8v62 by Molmil
Structure of the Human Respirovirus 3 Fusion Protein Bound to Camelid Nanobodies 1D10 and 4C06
分子名称: Camelid nanobody 1D10, Camelid nanobody 4C06, Fusion glycoprotein F0
著者Johnson, N.J, Ramamohan, A.R, McLellan, J.S.
登録日2023-12-01
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for potent neutralization of human respirovirus type 3 by protective single-domain camelid antibodies.
Nat Commun, 15, 2024
8U1R
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BU of 8u1r by Molmil
Prefusion-stabilized Langya virus F protein, variant G99C/I109C
分子名称: Fusion glycoprotein F
著者Byrne, P.O, McLellan, J.S.
登録日2023-09-01
公開日2023-12-27
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Prefusion stabilization of the Hendra and Langya virus F proteins.
J.Virol., 98, 2024
8U1G
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BU of 8u1g by Molmil
Prefusion-stabilized SARS-CoV-2 S2 subunit
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
著者Hsieh, C.-L, McLellan, J.S.
登録日2023-08-31
公開日2024-01-24
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Prefusion-stabilized SARS-CoV-2 S2-only antigen provides protection against SARS-CoV-2 challenge.
Nat Commun, 15, 2024
8V5A
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BU of 8v5a by Molmil
Prefusion-stabilized Respirovirus type 3 Fusion protein
分子名称: Camelid nanobody 4C06, Fusion glycoprotein F0
著者Johnson, N.V, McLellan, J.S.
登録日2023-11-30
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Universal paramyxovirus vaccine design by stabilizing regions involved in structural transformation of the fusion protein.
Nat Commun, 15, 2024
6U7K
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BU of 6u7k by Molmil
Prefusion structure of PEDV spike
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Wrapp, D, McLellan, J.S.
登録日2019-09-03
公開日2019-09-18
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献The 3.1-Angstrom Cryo-electron Microscopy Structure of the Porcine Epidemic Diarrhea Virus Spike Protein in the Prefusion Conformation.
J.Virol., 93, 2019
6UOE
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BU of 6uoe by Molmil
3-25 Fab germline-reversion variant bound to an HCMV gB-derived peptide
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-25 Fab heavy chain, 3-25 Fab light chain, ...
著者Wrapp, D, McLellan, J.S.
登録日2019-10-14
公開日2020-07-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step.
Plos Pathog., 16, 2020
5WB0
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BU of 5wb0 by Molmil
Crystal structure of human metapneumovirus fusion glycoprotein stabilized in the prefusion state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ...
著者Battles, M.B, McLellan, J.S.
登録日2017-06-27
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Structure and immunogenicity of pre-fusion-stabilized human metapneumovirus F glycoprotein.
Nat Commun, 8, 2017
8TCO
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BU of 8tco by Molmil
HCMV Trimer in complex with CS2it1p2_F7K Fab and CS4tt1p1_E3K Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CS2it1p2_F7K Fab heavy chain, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2023-07-02
公開日2023-08-09
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer.
Immunity, 56, 2023
8TEA
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BU of 8tea by Molmil
HCMV Pentamer in complex with CS2pt1p2_A10L Fab and CS3pt1p4_C1L Fab
分子名称: CS2pt1p2_A10L Fab heavy chain, CS2pt1p2_A10L Fab light chain, CS3pt1p4_C1L Fab heavy chain, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2023-07-05
公開日2023-08-09
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer.
Immunity, 56, 2023
5VZR
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BU of 5vzr by Molmil
Crystal Structure of MERS-CoV neutralizing antibody G4 Fab
分子名称: G4 antibody heavy chain, G4 antibody light chain, GLYCEROL
著者Wang, N, Wrapp, D, McLellan, J.S.
登録日2017-05-29
公開日2017-08-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6WAQ
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BU of 6waq by Molmil
Crystal structure of the SARS-CoV-1 RBD bound by the cross-reactive single-domain antibody SARS VHH-72
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, nanobody SARS VHH-72
著者Wrapp, D, McLellan, J.S.
登録日2020-03-25
公開日2020-04-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.
Cell, 181, 2020
6VSB
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BU of 6vsb by Molmil
Prefusion 2019-nCoV spike glycoprotein with a single receptor-binding domain up
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Wrapp, D, Wang, N, Corbett, K.S, Goldsmith, J.A, Hsieh, C, Abiona, O, Graham, B.S, McLellan, J.S.
登録日2020-02-10
公開日2020-02-26
最終更新日2021-01-27
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.
Science, 367, 2020
6WAR
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BU of 6war by Molmil
Crystal structure of the MERS-CoV RBD bound by the neutralizing single-domain antibody MERS VHH-55
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein, nanobody MERS VHH-55
著者Wrapp, D, Torres, G.M, McLellan, J.S.
登録日2020-03-25
公開日2020-04-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.
Cell, 181, 2020
6VKM
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BU of 6vkm by Molmil
Crystal Structure of Stabilized GP from Makona Variant of Ebola Virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Virion spike glycoprotein
著者Gilman, M.S.A, Rutten, L, Langedijk, J.P.M, McLellan, J.S.
登録日2020-01-21
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure-Based Design of Prefusion-Stabilized Filovirus Glycoprotein Trimers.
Cell Rep, 30, 2020
6VKF
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BU of 6vkf by Molmil
CCHFV GP38 (IbAr10200)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GP38
著者Mishra, A.K, McLellan, J.S.
登録日2020-01-20
公開日2020-02-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.524 Å)
主引用文献Structure and Characterization of Crimean-Congo Hemorrhagic Fever Virus GP38.
J.Virol., 94, 2020
5W23
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BU of 5w23 by Molmil
Crystal Structure of RSV F in complex with 5C4 Fab
分子名称: 5C4 Fab heavy chain, 5C4 Fab light chain, Fusion glycoprotein F0, ...
著者Battles, M.B, McLellan, J.S.
登録日2017-06-05
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein.
Nat Commun, 8, 2017

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件を2024-08-21に公開中

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