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8V5A

Prefusion-stabilized Respirovirus type 3 Fusion protein

This is a non-PDB format compatible entry.
Summary for 8V5A
Entry DOI10.2210/pdb8v5a/pdb
EMDB information42981
DescriptorFusion glycoprotein F0, Camelid nanobody 4C06 (2 entities in total)
Functional Keywordsfusion protein, viral glycoprotein, membrane fusion, viral protein, viral protein-immune system complex, viral protein/immune system
Biological sourceHuman respirovirus 3
More
Total number of polymer chains6
Total formula weight199907.12
Authors
Johnson, N.V.,McLellan, J.S. (deposition date: 2023-11-30, release date: 2024-06-19)
Primary citationLangedijk, J.P.M.,Cox, F.,Johnson, N.V.,van Overveld, D.,Le, L.,van den Hoogen, W.,Voorzaat, R.,Zahn, R.,van der Fits, L.,Juraszek, J.,McLellan, J.S.,Bakkers, M.J.G.
Universal paramyxovirus vaccine design by stabilizing regions involved in structural transformation of the fusion protein.
Nat Commun, 15:4629-4629, 2024
Cited by
PubMed: 38821950
DOI: 10.1038/s41467-024-48059-w
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3 Å)
Structure validation

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