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PDB: 209 件

2G6V
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The crystal structure of ribD from Escherichia coli
分子名称: Riboflavin biosynthesis protein ribD
著者Stenmark, P, Moche, M, Gurmu, D, Nordlund, P, Structural Proteomics in Europe (SPINE)
登録日2006-02-25
公開日2007-02-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Crystal Structure of the Bifunctional Deaminase/Reductase RibD of the Riboflavin Biosynthetic Pathway in Escherichia coli: Implications for the Reductive Mechanism.
J.Mol.Biol., 373, 2007
2VO1
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CRYSTAL STRUCTURE OF THE SYNTHETASE DOMAIN OF HUMAN CTP SYNTHETASE
分子名称: CTP SYNTHASE 1, SULFATE ION
著者Stenmark, P, Kursula, P, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Flodin, S, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Kotenyoa, T, Moche, M, Nilsson-Ehle, P, Ogg, D, Persson, C, Sagemark, J, Schuler, H, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Nordlund, P.
登録日2008-02-08
公開日2008-03-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the Synthetase Domain of Human Ctp Synthetase, a Target for Anticancer Therapy.
Acta Crystallogr.,Sect.F, 62, 2006
2VD6
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Human adenylosuccinate lyase in complex with its substrate N6-(1,2- Dicarboxyethyl)-AMP, and its products AMP and fumarate.
分子名称: 2-[9-(3,4-DIHYDROXY-5-PHOSPHONOOXYMETHYL-TETRAHYDRO-FURAN-2-YL)-9H-PURIN-6-YLAMINO]-SUCCINIC ACID, ADENOSINE MONOPHOSPHATE, ADENYLOSUCCINATE LYASE, ...
著者Stenmark, P, Moche, M, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nilsson, M, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Tresaugues, L, van den Berg, S, Weigelt, J, Welin, M, Nordlund, P, Structural Genomics Consortium (SGC)
登録日2007-09-30
公開日2007-10-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Human Adenylosuccinate Lyase in Complex with its Substrate N6-(1,2-Dicarboxyethyl)-AMP, and its Products AMP and Fumarate.
To be Published
2J4E
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THE ITP COMPLEX OF HUMAN INOSINE TRIPHOSPHATASE
分子名称: INOSINE 5'-TRIPHOSPHATE, INOSINE TRIPHOSPHATE PYROPHOSPHATASE, INOSINIC ACID, ...
著者Stenmark, P, Kursula, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmbergschiavone, L, Hogbom, M, Kotenyova, T, Landry, R, Loppnau, P, Magnusdottir, A, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Thorsell, A.G, Schuler, H, Van Den Berg, S, Wallden, K, Weigelt, J, Nordlund, P.
登録日2006-08-29
公開日2006-09-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Human Inosine Triphosphatase: Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T.
J.Biol.Chem., 282, 2007
1CIS
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CONTEXT DEPENDENCE OF PROTEIN SECONDARY STRUCTURE FORMATION. THE THREE-DIMENSIONAL STRUCTURE AND STABILITY OF A HYBRID BETWEEN CHYMOTRYPSIN INHIBITOR 2 AND HELIX E FROM SUBTILISIN CARLSBERG
分子名称: HYBRID PROTEIN FORMED FROM CHYMOTRYPSIN INHIBITOR-2
著者Osmark, P, Sorensen, P, Poulsen, F.M.
登録日1993-04-23
公開日1993-10-31
最終更新日2024-04-10
実験手法SOLUTION NMR
主引用文献Context dependence of protein secondary structure formation: the three-dimensional structure and stability of a hybrid between chymotrypsin inhibitor 2 and helix E from subtilisin Carlsberg.
Biochemistry, 32, 1993
2BZN
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Crystal structure of human guanosine monophosphate reductase 2 GMPR2 in complex with IMP
分子名称: GMP REDUCTASE 2, INOSINIC ACID
著者Stenmark, P, Kursula, P, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Graslund, S, Hammarstrom, M, Hallberg, B.M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Ogg, D, Persson, C, Sagemark, J, Schuler, H, Sundstrom, M, Thorsell, A, Weigelt, J.
登録日2005-08-19
公開日2005-09-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Cofactor Mobility Determines Reaction Outcome in the Impdh and Gmpr (Beta-Alpha)(8) Barrel Enzymes.
Nat.Chem.Biol., 7, 2011
2J91
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Crystal structure of Human Adenylosuccinate Lyase in complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, ADENYLOSUCCINATE LYASE, CHLORIDE ION, ...
著者Stenmark, P, Moche, M, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Johansson, I, Karlberg, T, Kosinska, U, Kotenyova, T, Magnusdottir, A, Nilsson, M.E, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Uppsten, M, Thorsell, A.G, van Den Berg, S, Wallden, K, Weigelt, J, Nordlund, P.
登録日2006-11-01
公開日2006-11-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Human Adenylosuccinate Lyase
To be Published
2J67
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The TIR domain of human Toll-Like Receptor 10 (TLR10)
分子名称: TOLL LIKE RECEPTOR 10
著者Stenmark, P, Ogg, D, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Johansson, I, Karlberg, T, Kotenyova, T, Magnusdottir, A, Nilsson, M.E, Nilsson-Ehle, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Welin, M, Nordlund, P.
登録日2006-09-26
公開日2006-09-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Crystal Structure of the Human Toll-Like Receptor 10 Cytoplasmic Domain Reveals a Putative Signaling Dimer.
J.Biol.Chem., 283, 2008
2CAR
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Crystal Structure Of Human Inosine Triphosphatase
分子名称: INOSINE TRIPHOSPHATE PYROPHOSPHATASE
著者Stenmark, P, Kursula, P, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Hogbom, M, Holmberg Schiavone, L, Kotenyova, T, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Schuler, H, Sundstrom, M, Thorsell, A.G, van den Berg, S, Weigelt, J, Nordlund, P.
登録日2005-12-22
公開日2006-01-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.09 Å)
主引用文献Crystal Structure of Human Inosine Triphosphatase. Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T.
J.Biol.Chem., 282, 2007
2VXR
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Crystal Structure of the Botulinum Neurotoxin serotype G binding domain
分子名称: BOTULINUM NEUROTOXIN TYPE G, GLYCEROL, SULFATE ION
著者Stenmark, P, Dupuy, J, Stevens, R.C.
登録日2008-07-08
公開日2009-07-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the Botulinum Neurotoxin Type G Binding Domain: Insight Into Cell Surface Binding.
J.Mol.Biol., 397, 2010
2CL3
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Crystal structure of human Cleavage and Polyadenylation Specificity Factor 5 (CPSF5)
分子名称: CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 5
著者Stenmark, P, Hogbom, M, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Kotenyova, T, Magnusdottir, A, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Nordlund, P.
登録日2006-04-25
公開日2006-05-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Crystal Structure of Human Cleavage and Polyadenylation Specific Factor-5 Reveals a Dimeric Nudix Protein with a Conserved Catalytic Site.
Proteins, 73, 2008
1BTV
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STRUCTURE OF BET V 1, NMR, 20 STRUCTURES
分子名称: BET V 1
著者Osmark, P, Poulsen, F.M, Gajhede, M, Larsen, J.N, Spangfort, M.D.
登録日1997-01-30
公開日1997-08-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献X-ray and NMR structure of Bet v 1, the origin of birch pollen allergy.
Nat.Struct.Biol., 3, 1996
2VU9
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CRYSTAL STRUCTURE OF BOTULINUM NEUROTOXIN SEROTYPE A BINDING DOMAIN IN COMPLEX WITH GT1B
分子名称: BOTULINUM NEUROTOXIN A HEAVY CHAIN, MAGNESIUM ION, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Stenmark, P, Dupuy, J, Stevens, R.C.
登録日2008-05-22
公開日2008-08-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of Botulinum Neurotoxin Type a in Complex with the Cell Surface Co-Receptor Gt1B- Insight Into the Toxin-Neuron Interaction.
Plos Pathog., 4, 2008
2VUA
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Crystal Structure of the Botulinum Neurotoxin Serotype A binding domain
分子名称: BOTULINUM NEUROTOXIN A HEAVY CHAIN
著者Stenmark, P, Dupuy, J, Stevens, R.C.
登録日2008-05-22
公開日2008-08-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of Botulinum Neurotoxin Type a in Complex with the Cell Surface Co-Receptor Gt1B- Insight Into the Toxin-Neuron Interaction.
Plos Pathog., 4, 2008
1XA4
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Crystal structure of CaiB, a type III CoA transferase in carnitine metabolism
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COENZYME A, Crotonobetainyl-CoA:carnitine CoA-transferase, ...
著者Stenmark, P, Gurmu, D, Nordlund, P.
登録日2004-08-25
公開日2004-11-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of CaiB, a Type-III CoA Transferase in Carnitine Metabolism
Biochemistry, 43, 2004
1XA3
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Crystal structure of CaiB, a type III CoA transferase in carnitine metabolism
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Crotonobetainyl-CoA:carnitine CoA-transferase, SULFATE ION
著者Stenmark, P, Gurmu, D, Nordlund, P, Structural Proteomics in Europe (SPINE)
登録日2004-08-25
公開日2004-11-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of CaiB, a Type-III CoA Transferase in Carnitine Metabolism
Biochemistry, 43, 2004
2VH9
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CRYSTAL STRUCTURE OF NXG1-DELTAYNIIG IN COMPLEX WITH XLLG, A XYLOGLUCAN DERIVED OLIGOSACCHARIDE
分子名称: CELLULASE, GLYCEROL, ZINC ION, ...
著者Czjzek, M, Mark, P, Baumann, M.J, Eklof, J.M, Michel, G, Brumer, H.
登録日2007-11-20
公開日2008-11-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Analysis of Nasturtium Tmnxg1 Complexes by Crystallography and Molecular Dynamics Provides Detailed Insight Into Substrate Recognition by Family Gh16 Xyloglucan Endo-Transglycosylases and Endo-Hydrolases.
Proteins, 75, 2009
2W2D
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Crystal Structure of a Catalytically Active, Non-toxic Endopeptidase Derivative of Clostridium botulinum Toxin A
分子名称: ACETATE ION, BOTULINUM NEUROTOXIN A HEAVY CHAIN, BOTULINUM NEUROTOXIN A LIGHT CHAIN, ...
著者Masuyer, G, Thiyagarajan, N, James, P.L, Marks, P.M.H, Chaddock, J.A, Acharya, K.R.
登録日2008-10-29
公開日2009-03-24
最終更新日2022-05-04
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Crystal Structure of a Catalytically Active, Non-Toxic Endopeptidase Derivative of Clostridium Botulinum Toxin A.
Biochem.Biophys.Res.Commun., 381, 2009
2FVZ
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Human Inositol Monophosphosphatase 2
分子名称: Inositol monophosphatase 2
著者Ogg, D, Hallberg, B.M, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Graslund, S, Hammarstrom, M, Hogbom, M, Holmberg-Schiavone, L, Kotenyova, T, Kursula, P, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Van Den Berg, S, Weigelt, J, Thorsell, A.G, Structural Genomics Consortium (SGC)
登録日2006-01-31
公開日2006-02-21
最終更新日2018-05-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of Human Inositol Monophosphatase 2
To be published
2GK9
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Human Phosphatidylinositol-4-phosphate 5-kinase, type II, gamma
分子名称: phosphatidylinositol-4-phosphate 5-kinase, type II, gamma
著者Uppenberg, J, Hogbom, M, Ogg, D, Arrowsmith, C, Berglund, H, Collins, R, Ehn, M, Flodin, S, Flores, A, Graslund, S, Holmberg-Schiavone, L, Edwards, A, Hammarstrom, M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Hallberg, B.M, Structural Genomics Consortium (SGC)
登録日2006-03-31
公開日2006-05-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Human Phosphatidylinositol-4-phosphate 5-kinase, type II, gamma
To be Published
2G62
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Crystal structure of human PTPA
分子名称: GLYCEROL, SULFATE ION, protein phosphatase 2A, ...
著者Magnusdottir, A, Stenmark, P, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Hogbom, M, Holmberg Schiavone, L, Kotenyova, T, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Nordlund, P.
登録日2006-02-24
公開日2006-04-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The crystal structure of a human PP2A phosphatase activator reveals a novel fold and highly conserved cleft implicated in protein-protein interactions.
J.Biol.Chem., 281, 2006
2FVV
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Human Diphosphoinositol polyphosphate phosphohydrolase 1
分子名称: CHLORIDE ION, Diphosphoinositol polyphosphate phosphohydrolase 1, INOSITOL HEXAKISPHOSPHATE, ...
著者Hallberg, B.M, Kursula, P, Ogg, D, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Flodin, S, Graslund, S, Hammarstrom, M, Hogbom, M, Holmberg-Schiavone, L, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, van den Berg, S, Weigelt, J, Persson, C, Structural Genomics Consortium (SGC)
登録日2006-01-31
公開日2006-03-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Crystal structure of human diphosphoinositol phosphatase 1
Proteins, 77, 2009
2G9N
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Structure of the DEAD domain of Human eukaryotic initiation factor 4A, eIF4A
分子名称: Eukaryotic initiation factor 4A-I
著者Hogbom, M, Ogg, D, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Uppenberg, J, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日2006-03-07
公開日2006-03-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5, 2010
6EKT
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Structure of P47 from Clostridium botulinum A2
分子名称: p-47 protein
著者Berntsson, R.P, Stenmark, P.
登録日2017-09-27
公開日2017-10-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structures of OrfX2 and P47 from a Botulinum neurotoxin OrfX-type gene cluster.
FEBS Lett., 591, 2017
6RLW
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Structure of the human 8-oxoguanine DNA Glycosylase hOGG1 in complex with inhibitor TH5487
分子名称: 4-(4-bromanyl-2-oxidanylidene-3~{H}-benzimidazol-1-yl)-~{N}-(4-iodophenyl)piperidine-1-carboxamide, N-glycosylase/DNA lyase
著者Masuyer, G, Stenmark, P.
登録日2019-05-03
公開日2020-07-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Targeting OGG1 arrests cancer cell proliferation by inducing replication stress.
Nucleic Acids Res., 48, 2020

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