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PDB: 1326 results

6R18
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BU of 6r18 by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 11a
Descriptor: CHLORIDE ION, Cereblon isoform 4, PHOSPHATE ION, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-14
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R19
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BU of 6r19 by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 20a
Descriptor: Cereblon isoform 4, PHOSPHATE ION, S-Thalidomide, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-14
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R1A
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BU of 6r1a by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 20b
Descriptor: Cereblon isoform 4, PHOSPHATE ION, S-Thalidomide, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-14
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R1K
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BU of 6r1k by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 7c
Descriptor: Cereblon isoform 4, PHOSPHATE ION, ZINC ION, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-14
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R1W
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BU of 6r1w by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 16b
Descriptor: (4-azanylcyclohexyl)methyl ~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]carbamate, Cereblon isoform 4, PHOSPHATE ION, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-15
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R1C
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BU of 6r1c by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 12a
Descriptor: 4-[[4-[[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamoyloxymethyl]phenyl]methylamino]-4-oxidanylidene-butanoic acid, ASPARTIC ACID, CHLORIDE ION, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-14
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
2P6W
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BU of 2p6w by Molmil
Crystal structure of a glycosyltransferase involved in the glycosylation of the major capsid of PBCV-1
Descriptor: CITRATE ANION, MANGANESE (II) ION, Putative glycosyltransferase (Mannosyltransferase) involved in glycosylating the PBCV-1 major capsid protein
Authors:Zhang, Y, Ye, X, Van Etten, J.L, Rossmann, M.G.
Deposit date:2007-03-19
Release date:2007-08-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure and function of a chlorella virus-encoded glycosyltransferase.
Structure, 15, 2007
4LHD
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BU of 4lhd by Molmil
Crystal structure of Synechocystis sp. PCC 6803 glycine decarboxylase (P-protein), holo form with pyridoxal-5'-phosphate and glycine, closed flexible loop
Descriptor: 1,2-ETHANEDIOL, BICARBONATE ION, GLYCINE, ...
Authors:Hasse, D, Andersson, E, Carlsson, G, Masloboy, A, Hagemann, M, Bauwe, H, Andersson, I.
Deposit date:2013-07-01
Release date:2013-10-16
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.7959 Å)
Cite:Structure of the Homodimeric Glycine Decarboxylase P-protein from Synechocystis sp. PCC 6803 Suggests a Mechanism for Redox Regulation.
J.Biol.Chem., 288, 2013
1KMA
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BU of 1kma by Molmil
NMR Structure of the Domain-I of the Kazal-type Thrombin Inhibitor Dipetalin
Descriptor: DIPETALIN
Authors:Schlott, B, Wohnert, J, Icke, C, Hartmann, M, Ramachandran, R, Guhrs, K.-H, Glusa, E, Flemming, J, Gorlach, M, Grosse, F, Ohlenschlager, O.
Deposit date:2001-12-14
Release date:2002-05-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Interaction of Kazal-type inhibitor domains with serine proteinases: biochemical and structural studies.
J.Mol.Biol., 318, 2002
4LHC
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BU of 4lhc by Molmil
Crystal structure of Synechocystis sp. PCC 6803 glycine decarboxylase (P-protein), holo form with pyridoxal-5'-phosphate and glycine
Descriptor: 1,2-ETHANEDIOL, BICARBONATE ION, BICINE, ...
Authors:Hasse, D, Andersson, E, Carlsson, G, Masloboy, A, Hagemann, M, Bauwe, H, Andersson, I.
Deposit date:2013-07-01
Release date:2013-10-16
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Structure of the Homodimeric Glycine Decarboxylase P-protein from Synechocystis sp. PCC 6803 Suggests a Mechanism for Redox Regulation.
J.Biol.Chem., 288, 2013
2J4S
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BU of 2j4s by Molmil
P450 BM3 heme domain in complex with DMSO
Descriptor: BIFUNCTIONAL P-450:NADPH-P450 REDUCTASE, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Kuper, J, Tuck-Seng, W, Roccatano, D, Wilmanns, M, Schwaneberg, U.
Deposit date:2006-09-05
Release date:2007-05-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Understanding a Mechanism of Organic Cosolvent Inactivation in Heme Monooxygenase P450 Bm-3.
J.Am.Chem.Soc., 129, 2007
1J0X
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BU of 1j0x by Molmil
Crystal structure of the rabbit muscle glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, glyceraldehyde-3-phosphate dehydrogenase
Authors:Cowan-Jacob, S.W, Kaufmann, M, Anselmo, A.N, Stark, W, Grutter, M.G.
Deposit date:2002-11-25
Release date:2003-12-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of rabbit-muscle glyceraldehyde-3-phosphate dehydrogenase.
Acta Crystallogr.,Sect.D, 59, 2003
4HEJ
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BU of 4hej by Molmil
Discovery of Selective and Potent Inhibitors of Gram-positive Bacterial Thymidylate Kinase (TMK): Compund 16
Descriptor: 5-methyl-1-[(3S)-1-{3-[3-(trifluoromethyl)phenoxy]benzyl}piperidin-3-yl]pyrimidine-2,4(1H,3H)-dione, Thymidylate kinase
Authors:Martinez-Botella, G, Breen, J, Duffy, J, Dumas, J, Geng, B, Gowers, I, Green, O, Guler, S, Hentemann, M, Hernandez-Juan, F, Joseph-McCarthy, D, Kawatkar, S, Larsen, N, Lazari, O, Loch, J, Macritchie, J.
Deposit date:2012-10-03
Release date:2012-10-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of Selective and Potent Inhibitors of Gram-Positive Bacterial Thymidylate Kinase (TMK).
J.Med.Chem., 55, 2012
1OOT
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BU of 1oot by Molmil
Crystal structure of the SH3 domain from a S. cerevisiae hypothetical 40.4 kDa protein at 1.39 A resolution
Descriptor: CHLORIDE ION, Hypothetical 40.4 kDa protein in PES4-HIS2 intergenic region
Authors:Kursula, P, Lehmann, F, Song, Y.H, Wilmanns, M.
Deposit date:2003-03-04
Release date:2004-04-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Crystal structure of the SH3 domain from a S. cerevisiae hypothetical 40.4 kDa protein at 1.39 A resolution
To be Published
2P73
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BU of 2p73 by Molmil
crystal structure of a glycosyltransferase involved in the glycosylation of the major capsid of PBCV-1
Descriptor: MANGANESE (II) ION, Putative glycosyltransferase (Mannosyltransferase) involved in glycosylating the PBCV-1 major capsid protein, URIDINE-5'-DIPHOSPHATE
Authors:Zhang, Y, Xiang, Y, Van Etten, J.L, Rossmann, M.G.
Deposit date:2007-03-19
Release date:2007-08-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and function of a chlorella virus-encoded glycosyltransferase.
Structure, 15, 2007
2P72
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BU of 2p72 by Molmil
crystal structure of a glycosyltransferase involved in the glycosylation of the major capsid of PBCV-1
Descriptor: MANGANESE (II) ION, Putative glycosyltransferase (Mannosyltransferase) involved in glycosylating the PBCV-1 major capsid protein, URIDINE-5'-DIPHOSPHATE-GLUCOSE
Authors:Zhang, Y, Xiang, Y, Van Etten, J.L, Rossmann, M.G.
Deposit date:2007-03-19
Release date:2007-08-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and function of a chlorella virus-encoded glycosyltransferase.
Structure, 15, 2007
4KAB
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BU of 4kab by Molmil
FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH 3-Methyl-1,4-dihydro-pyrazolo[4,5-c]pyrazole
Descriptor: 3-methyl-1,5-dihydropyrazolo[4,3-c]pyrazole, Focal adhesion kinase 1
Authors:Musil, D, Graedler, U, Heinrich, T, Lehmann, M, Dresing, V.
Deposit date:2013-04-22
Release date:2013-09-11
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Fragment-based discovery of focal adhesion kinase inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
3R9A
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BU of 3r9a by Molmil
Human alanine-glyoxylate aminotransferase in complex with the TPR domain of human PEX5P
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Peroxisomal targeting signal 1 receptor, Serine--pyruvate aminotransferase
Authors:Fodor, K, Wilmanns, M.
Deposit date:2011-03-25
Release date:2011-05-11
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Molecular requirements for peroxisomal targeting of alanine-glyoxylate aminotransferase as an essential determinant in primary hyperoxaluria type 1
Plos Biol., 10, 2012
1J7M
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BU of 1j7m by Molmil
The Third Fibronectin Type II Module from Human Matrix Metalloproteinase 2
Descriptor: MATRIX METALLOPROTEINASE 2
Authors:Briknarova, K, Gehrmann, M, Banyai, L, Tordai, H, Patthy, L, Llinas, M.
Deposit date:2001-05-17
Release date:2001-05-30
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Gelatin-binding region of human matrix metalloproteinase-2: solution structure, dynamics, and function of the COL-23 two-domain construct.
J.Biol.Chem., 276, 2001
4I8A
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BU of 4i8a by Molmil
Alanine-glyoxylate aminotransferase variant S187F
Descriptor: GLYCEROL, Serine-pyruvate aminotransferase
Authors:Fodor, K, Oppici, E, Williams, C, Cellini, B, Wilmanns, M.
Deposit date:2012-12-03
Release date:2013-05-01
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications.
Proteins, 81, 2013
2J9Q
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BU of 2j9q by Molmil
A novel conformation for the TPR domain of pex5p
Descriptor: PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR, STRONTIUM ION
Authors:Stanley, W.A, Wilmanns, M, Kursula, P.
Deposit date:2006-11-15
Release date:2007-04-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A Previously Unobserved Conformation for the Human Pex5P Receptor Suggests Roles for Intrinsic Flexibility and Rigid Domain Motions in Ligand Binding
Bmc Struct.Biol., 7, 2007
2AO7
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BU of 2ao7 by Molmil
Adam10 Disintegrin and cysteine- rich domain
Descriptor: ADAM 10, SULFATE ION
Authors:Janes, P.W, Saha, N, Barton, W.A, Kolev, M.V, Wimmer-Kleikamp, S.H, Nievergall, E, Blobel, C.P, Himanen, J.-P, Lackmann, M, Nikolov, D.B.
Deposit date:2005-08-12
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans.
Cell(Cambridge,Mass.), 123, 2005
1S74
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BU of 1s74 by Molmil
SOLUTION STRUCTURE OF A DNA DUPLEX CONTAINING AN ALPHA-ANOMERIC ADENOSINE: INSIGHTS INTO SUBSTRATE RECOGNITION BY ENDONUCLEASE IV
Descriptor: 5'-D(*CP*GP*TP*CP*GP*TP*GP*GP*AP*C)-3', 5'-D(*GP*TP*CP*CP*(A3A)P*CP*GP*AP*CP*G)-3'
Authors:Aramini, J.M, Cleaver, S.H, Pon, R.T, Cunningham, R.P, Germann, M.W.
Deposit date:2004-01-28
Release date:2004-04-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure of a DNA Duplex Containing an alpha-Anomeric Adenosine: Insights into Substrate Recognition by Endonuclease IV.
J.Mol.Biol., 338, 2004
2C0L
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BU of 2c0l by Molmil
TPR DOMAIN OF HUMAN PEX5P IN COMPLEX WITH HUMAN MSCP2
Descriptor: NONSPECIFIC LIPID-TRANSFER PROTEIN, PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR
Authors:Stanley, W.A, Kursula, P, Wilmanns, M.
Deposit date:2005-09-05
Release date:2006-11-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Recognition of a Functional Peroxisome Type 1 Target by the Dynamic Import Receptor Pex5P.
Mol.Cell, 24, 2006
1NCH
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BU of 1nch by Molmil
STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS
Descriptor: N-CADHERIN, YTTERBIUM (III) ION
Authors:Shapiro, L, Fannon, A.M, Kwong, P.D, Thompson, A, Lehmann, M.S, Grubel, G, Legrand, J.-F, Als-Nielsen, J, Colman, D.R, Hendrickson, W.A.
Deposit date:1995-03-23
Release date:1995-07-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of cell-cell adhesion by cadherins.
Nature, 374, 1995

223532

數據於2024-08-07公開中

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