3R9A
Human alanine-glyoxylate aminotransferase in complex with the TPR domain of human PEX5P
Replaces: 3IMZSummary for 3R9A
Entry DOI | 10.2210/pdb3r9a/pdb |
Descriptor | Serine--pyruvate aminotransferase, Peroxisomal targeting signal 1 receptor, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total) |
Functional Keywords | tpr-domain, protein-protein complex, peroxisome, aminotransf pyruvate, transferase, disease mutation, membrane, peroxiso biogenesis disorder, protein transport, tpr repeat, transpo zellweger syndrome, transferase-transport protein complex, mitochondrion, pyridoxal phosphate, transferase/transport protein |
Biological source | Homo sapiens (human) More |
Cellular location | Peroxisome: P21549 Cytoplasm: P50542 |
Total number of polymer chains | 4 |
Total formula weight | 159308.73 |
Authors | Fodor, K.,Wilmanns, M. (deposition date: 2011-03-25, release date: 2011-05-11, Last modification date: 2012-05-02) |
Primary citation | Fodor, K.,Wolf, J.,Erdmann, R.,Schliebs, W.,Wilmanns, M. Molecular requirements for peroxisomal targeting of alanine-glyoxylate aminotransferase as an essential determinant in primary hyperoxaluria type 1 Plos Biol., 10:e1001309-e1001309, 2012 Cited by PubMed: 22529745DOI: 10.1371/journal.pbio.1001309 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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