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4I8A

Alanine-glyoxylate aminotransferase variant S187F

Summary for 4I8A
Entry DOI10.2210/pdb4i8a/pdb
Related1H0C 1JO4
DescriptorSerine-pyruvate aminotransferase, GLYCEROL (2 entities in total)
Functional Keywordsaminotransferase, primary hyperoxaluria type 1, peroxisome, transferase
Biological sourceHomo sapiens (human)
Cellular locationPeroxisome: P21549
Total number of polymer chains4
Total formula weight175113.94
Authors
Fodor, K.,Oppici, E.,Williams, C.,Cellini, B.,Wilmanns, M. (deposition date: 2012-12-03, release date: 2013-05-01, Last modification date: 2023-12-06)
Primary citationOppici, E.,Fodor, K.,Paiardini, A.,Williams, C.,Voltattorni, C.B.,Wilmanns, M.,Cellini, B.
Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications.
Proteins, 81:1457-1465, 2013
Cited by
PubMed: 23589421
DOI: 10.1002/prot.24300
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.9 Å)
Structure validation

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