3CT1
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4K8A
| Fragment-based discovery of Focal Adhesion Kinase Inhibitors | 分子名称: | 3-bromo-5-(2H-tetrazol-5-yl)pyridine, Focal adhesion kinase 1 | 著者 | Graedler, U, Bomke, J, Musil, D, Dresing, V, Lehmann, M, Hoelzemann, G, Esdar, C, Krier, M, Heinrich, T. | 登録日 | 2013-04-18 | 公開日 | 2013-09-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Fragment-based discovery of focal adhesion kinase inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
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2YMD
| Crystal structure of a mutant binding protein (5HTBP-AChBP) in complex with serotonin (5-hydroxytryptamine) | 分子名称: | GLYCEROL, PHOSPHATE ION, SEROTONIN, ... | 著者 | Kesters, D, Thompson, A.J, Brams, M, Elk, R.v, Spurny, R, Geitmann, M, Villalgordo, J.M, Guskov, A, Danielson, U.H, Lummis, S.C.R, Smit, A.B, Ulens, C. | 登録日 | 2012-10-09 | 公開日 | 2012-12-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structural Basis of Ligand Recognition in 5-Ht(3) Receptors. Embo Rep., 14, 2013
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5ADO
| Crystal structure of the paraoxon-modified A.17 antibody FAB fragment - Light chain S35R mutant | 分子名称: | DIETHYL PHOSPHONATE, FAB A.17 | 著者 | Chatziefthimiou, S.D, Smirnov, I.V, Golovin, A.V, Stepanova, A.V, Peng, Y, Zolotareva, O.I, Belogurov, A.A, Ponomarenko, N.A, Blackburn, G.M, Gabibov, A.A, Lerner, R, Wilmanns, M. | 登録日 | 2015-08-21 | 公開日 | 2016-11-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Robotic Qm/Mm-Driven Maturation of Antibody Combining Sites. Sci.Adv., 2, 2016
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5AF7
| 3-Sulfinopropionyl-coenzyme A (3SP-CoA) desulfinase from Advenella mimigardefordensis DPN7T: crystal structure and function of a desulfinase with an acyl-CoA dehydrogenase fold. Native crystal structure | 分子名称: | ACYL-COA DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL | 著者 | Cianci, M, Schuermann, M, Meijers, R, Schneider, T.R, Steinbuechel, A. | 登録日 | 2015-01-20 | 公開日 | 2015-06-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | 3-Sulfinopropionyl-Coenzyme a (3Sp-Coa) Desulfinase from Advenella Mimigardefordensis Dpn7(T): Crystal Structure and Function of a Desulfinase with an Acyl-Coa Dehydrogenase Fold. Acta Crystallogr.,Sect.D, 71, 2015
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1Z9X
| Human DRP-1 kinase, W305S S308A D40 mutant, crystal form with 3 monomers in the asymmetric unit | 分子名称: | Death-associated protein kinase 2 | 著者 | Kursula, P, Lehmann, F, Shani, G, Kimchi, A, Wilmanns, M. | 登録日 | 2005-04-05 | 公開日 | 2006-10-24 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.93 Å) | 主引用文献 | A structural insight into the double-locking mechanism of the human death-associated DRP-1 kinase To be Published
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3CSQ
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4LCT
| Crystal Structure and Versatile Functional Roles of the COP9 Signalosome Subunit 1 | 分子名称: | COP9 signalosome complex subunit 1, SULFATE ION | 著者 | Lee, J.-H, Yi, L, Li, J, Schweitzer, K, Borgmann, M, Naumann, M, Wu, H. | 登録日 | 2013-06-23 | 公開日 | 2013-07-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure and versatile functional roles of the COP9 signalosome subunit 1. Proc.Natl.Acad.Sci.USA, 110, 2013
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1WYK
| SINDBIS VIRUS CAPSID PROTEIN (114-264) | 分子名称: | 1,4-DIETHYLENE DIOXIDE, FORMYL GROUP, SINDBIS VIRUS CAPSID PROTEIN | 著者 | Lee, S, Kuhn, R.J, Rossmann, M.G. | 登録日 | 1998-01-12 | 公開日 | 1998-04-29 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Probing the potential glycoprotein binding site of sindbis virus capsid protein with dioxane and model building. Proteins, 33, 1998
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1N9L
| Crystal structure of the Phot-LOV1 domain from Chlamydomonas reinhardtii in the dark state. | 分子名称: | FLAVIN MONONUCLEOTIDE, SULFATE ION, putative blue light receptor | 著者 | Fedorov, R, Schlichting, I, Hartmann, E, Domratcheva, T, Fuhrmann, M, Hegemann, P. | 登録日 | 2002-11-25 | 公開日 | 2003-06-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii. Biophys.J., 84, 2003
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1N9O
| Crystal structure of the Phot-LOV1 domain from Chlamydomonas reinhardtii in illuminated state. Composite data set. | 分子名称: | FLAVIN MONONUCLEOTIDE, SULFATE ION, putative blue light receptor | 著者 | Fedorov, R, Schlichting, I, Hartmann, E, Domratcheva, T, Fuhrmann, M, Hegemann, P. | 登録日 | 2002-11-25 | 公開日 | 2003-06-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii. Biophys.J., 84, 2003
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3CT0
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1ZX6
| High-resolution crystal structure of yeast Pin3 SH3 domain | 分子名称: | Ypr154wp | 著者 | Kursula, P, Kursula, I, Lehmann, F, Zou, P, Song, Y.H, Wilmanns, M. | 登録日 | 2005-06-07 | 公開日 | 2006-10-24 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural genomics of yeast SH3 domains To be Published
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2AB7
| Solution structures and characterization of HIV RRE IIB RNA targeting zinc finger proteins | 分子名称: | ZINC ION, ZNF29G29R | 著者 | Mishra, S.H, Shelley, C.M, Darby, M.K, Germann, M.W. | 登録日 | 2005-07-14 | 公開日 | 2005-08-02 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures and characterization of human immunodeficiency virus Rev responsive element IIB RNA targeting zinc finger proteins. Biopolymers, 83, 2006
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1ORV
| Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... | 著者 | Engel, M, Hoffmann, T, Wagner, L, Wermann, M, Heiser, U, Kiefersauer, R, Huber, R, Bode, W, Demuth, H.U, Brandstetter, H. | 登録日 | 2003-03-16 | 公開日 | 2003-05-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Crystal Structure of Dipeptidyl Peptidase IV (CD26) Reveals its Functional Regulation and Enzymatic Mechanism Proc.Natl.Acad.Sci.USA, 100, 2003
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3IGE
| Small outer capsid protein (Soc) from bacteriophage RB69 | 分子名称: | IMIDAZOLE, Soc small outer capsid protein | 著者 | Li, Q, Fokine, A, O'Donnell, E, Rao, V.B, Rossmann, M.G. | 登録日 | 2009-07-27 | 公開日 | 2009-12-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.254 Å) | 主引用文献 | Structure of the Small Outer Capsid Protein, Soc: A Clamp for Stabilizing Capsids of T4-like Phages J.Mol.Biol., 395, 2010
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3NWU
| Substrate induced remodeling of the active site regulates HtrA1 activity | 分子名称: | SULFATE ION, Serine protease HTRA1 | 著者 | Truebestein, L, Tennstaedt, A, Hauske, P, Krojer, T, Kaiser, M, Clausen, T, Ehrmann, M. | 登録日 | 2010-07-11 | 公開日 | 2011-02-23 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Substrate-induced remodeling of the active site regulates human HTRA1 activity. Nat.Struct.Mol.Biol., 18, 2011
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3NUM
| Substrate induced remodeling of the active site regulates HtrA1 activity | 分子名称: | Serine protease HTRA1 | 著者 | Truebestein, L, Tennstaedt, A, Hauske, P, Krojer, T, Kaiser, M, Clausen, T, Ehrmann, M. | 登録日 | 2010-07-07 | 公開日 | 2011-02-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Substrate-induced remodeling of the active site regulates human HTRA1 activity. Nat.Struct.Mol.Biol., 18, 2011
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3LCY
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3J2Y
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1YE8
| Crystal Structure of THEP1 from the hyperthermophile Aquifex aeolicus | 分子名称: | Hypothetical UPF0334 kinase-like protein AQ_1292, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Rossbach, M, Daumke, O, Klinger, C, Wittinghofer, A, Kaufmann, M. | 登録日 | 2004-12-28 | 公開日 | 2005-03-29 | 最終更新日 | 2014-11-12 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal structure of THEP1 from the hyperthermophile Aquifex aeolicus: a variation of the RecA fold BMC Struct.Biol., 5, 2005
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7CAT
| The NADPH binding site on beef liver catalase | 分子名称: | CATALASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Murthy, M.R.N, Reid III, T.J, Sicignano, A, Tanaka, N, Fita, I, Rossmann, M.G. | 登録日 | 1984-11-15 | 公開日 | 1985-04-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The NADPH binding site on beef liver catalase. Proc.Natl.Acad.Sci.USA, 82, 1985
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2XR1
| DIMERIC ARCHAEAL CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR WITH N-TERMINAL KH DOMAINS (KH-CPSF) FROM METHANOSARCINA MAZEI | 分子名称: | CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 100 KD SUBUNIT, ZINC ION | 著者 | Mir-Montazeri, B, Ammelburg, M, Forouzan, D, Lupas, A.N, Hartmann, M.D. | 登録日 | 2010-09-08 | 公開日 | 2010-10-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Crystal Structure of a Dimeric Archaeal Cleavage and Polyadenylation Specificity Factor. J.Struct.Biol., 173, 2011
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3J2Z
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7B9S
| Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex | 分子名称: | EccB5, EccC5, EccD5, ... | 著者 | Chojnowski, G, Ritter, C, Beckham, K.S.H, Mullapudi, E, Rettel, M, Savitski, M.M, Mortensen, S.A, Ziemianowicz, D, Kosinski, J, Wilmanns, M. | 登録日 | 2020-12-14 | 公開日 | 2021-07-07 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of the mycobacterial ESX-5 type VII secretion system pore complex. Sci Adv, 7, 2021
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