2Y85
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE WITH BOUND RCDRP
Summary for 2Y85
Entry DOI | 10.2210/pdb2y85/pdb |
Related | 2Y88 2Y89 |
Descriptor | PHOSPHORIBOSYL ISOMERASE A, SODIUM ION, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | isomerase, bifunctional enzyme, tryptophan biosynthesis, histidine biosynthesis, tim-barrel, aromatic amino acid biosynthesis |
Biological source | MYCOBACTERIUM TUBERCULOSIS |
Cellular location | Cytoplasm (By similarity): P60578 |
Total number of polymer chains | 4 |
Total formula weight | 104434.75 |
Authors | Kuper, J.,Geerlof, A.,Wilmanns, M. (deposition date: 2011-02-03, release date: 2011-03-02, Last modification date: 2023-12-20) |
Primary citation | Due, A.V.,Kuper, J.,Geerlof, A.,Kries, J.P.,Wilmanns, M. Bisubstrate Specificity in Histidine/Tryptophan Biosynthesis Isomerase from Mycobacterium Tuberculosis by Active Site Metamorphosis. Proc.Natl.Acad.Sci.USA, 108:3554-, 2011 Cited by PubMed: 21321225DOI: 10.1073/PNAS.1015996108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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