4Q42
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![BU of 4q42 by Molmil](/molmil-images/mine/4q42) | Crystal structure of Schistosoma mansoni arginase in complex with L-ornithine | Descriptor: | Arginase, GLYCEROL, L-ornithine, ... | Authors: | Hai, Y, Edwards, J.E, Van Zandt, M.C, Hoffmann, K.F, Christianson, D.W. | Deposit date: | 2014-04-12 | Release date: | 2014-07-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.051 Å) | Cite: | Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis. Biochemistry, 53, 2014
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4JQ9
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![BU of 4jq9 by Molmil](/molmil-images/mine/4jq9) | Dihydrolipoyl dehydrogenase of Escherichia coli pyruvate dehydrogenase complex | Descriptor: | CHLORIDE ION, Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Tietzel, M, Neumann, P, Meyer, D, Ficner, R, Tittmann, K. | Deposit date: | 2013-03-20 | Release date: | 2014-04-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Dihydrolipoyl dehydrogenase of Escherichia coli pyruvate dehydrogenase complex TO BE PUBLISHED
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3MOS
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![BU of 3mos by Molmil](/molmil-images/mine/3mos) | The structure of human Transketolase | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, SODIUM ION, ... | Authors: | Parthier, C, Tittmann, K. | Deposit date: | 2010-04-23 | Release date: | 2010-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The crystal structure of human transketolase and new insights into its mode of action. J.Biol.Chem., 285, 2010
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3IOG
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![BU of 3iog by Molmil](/molmil-images/mine/3iog) | Crystal structure of CphA N220G mutant with inhibitor 18 | Descriptor: | Beta-lactamase, GLYCEROL, SULFATE ION, ... | Authors: | Delbruck, H, Bebrone, C, Hoffmann, K.M.V. | Deposit date: | 2009-08-14 | Release date: | 2010-06-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-beta-lactamases J.Med.Chem., 53, 2010
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3IOF
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![BU of 3iof by Molmil](/molmil-images/mine/3iof) | Crystal structure of CphA N220G mutant with inhibitor 10a | Descriptor: | Beta-lactamase, GLYCEROL, SULFATE ION, ... | Authors: | Delbruck, H, Bebrone, C, Hoffmann, K.M.V. | Deposit date: | 2009-08-14 | Release date: | 2010-06-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-beta-lactamases J.Med.Chem., 53, 2010
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4KGD
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4KXX
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![BU of 4kxx by Molmil](/molmil-images/mine/4kxx) | Human transketolase in covalent complex with donor ketose D-sedoheptulose-7-phosphate | Descriptor: | (2R,3R,4S,5R,6S)-2,3,4,5,6,7-hexahydroxyheptyl dihydrogen phosphate, 1,2-ETHANEDIOL, MAGNESIUM ION, ... | Authors: | Neumann, P, Luedtke, S, Ficner, R, Tittmann, K. | Deposit date: | 2013-05-28 | Release date: | 2013-08-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.03 Å) | Cite: | Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate. Nat Chem, 5, 2013
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4KXU
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![BU of 4kxu by Molmil](/molmil-images/mine/4kxu) | Human transketolase in covalent complex with donor ketose D-fructose-6-phosphate | Descriptor: | 1,2-ETHANEDIOL, D-SORBITOL-6-PHOSPHATE, MAGNESIUM ION, ... | Authors: | Neumann, P, Luedtke, S, Ficner, R, Tittmann, K. | Deposit date: | 2013-05-28 | Release date: | 2013-08-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (0.98 Å) | Cite: | Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate. Nat Chem, 5, 2013
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4KXV
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![BU of 4kxv by Molmil](/molmil-images/mine/4kxv) | Human transketolase in covalent complex with donor ketose D-xylulose-5-phosphate, crystal 1 | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, D-XYLITOL-5-PHOSPHATE, ... | Authors: | Neumann, P, Luedtke, S, Ficner, R, Tittmann, K. | Deposit date: | 2013-05-28 | Release date: | 2013-08-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (0.97 Å) | Cite: | Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate. Nat Chem, 5, 2013
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7A9W
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![BU of 7a9w by Molmil](/molmil-images/mine/7a9w) | Structure of yeast Rmd9p in complex with 20nt target RNA | Descriptor: | CHLORIDE ION, Protein RMD9, mitochondrial, ... | Authors: | Hillen, H.S, Markov, D.A, Ireneusz, W.D, Hofmann, K.B, Cowan, A.T, Jones, J.L, Temiakov, D, Cramer, P, Anikin, M. | Deposit date: | 2020-09-02 | Release date: | 2021-04-07 | Last modified: | 2021-05-05 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3'-UTRs of yeast mitochondrial mRNAs. Proc.Natl.Acad.Sci.USA, 118, 2021
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7A9X
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![BU of 7a9x by Molmil](/molmil-images/mine/7a9x) | Structure of yeast Rmd9p in complex with 16nt target RNA | Descriptor: | CHLORIDE ION, Protein RMD9, mitochondrial, ... | Authors: | Hillen, H.S, Markov, D.A, Ireneusz, W.D, Hofmann, K.B, Cowan, A.T, Jones, J.L, Temiakov, D, Cramer, P, Anikin, M. | Deposit date: | 2020-09-02 | Release date: | 2021-04-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3'-UTRs of yeast mitochondrial mRNAs. Proc.Natl.Acad.Sci.USA, 118, 2021
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4WQC
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![BU of 4wqc by Molmil](/molmil-images/mine/4wqc) | Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - K208N mutant | Descriptor: | 1,2-ETHANEDIOL, HEME C, SULFATE ION, ... | Authors: | Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M. | Deposit date: | 2014-10-21 | Release date: | 2015-02-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION. J.Biol.Chem., 290, 2015
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3OC4
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![BU of 3oc4 by Molmil](/molmil-images/mine/3oc4) | Crystal Structure of a pyridine nucleotide-disulfide family oxidoreductase from the Enterococcus faecalis V583 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Oxidoreductase, pyridine nucleotide-disulfide family, ... | Authors: | Kumaran, D, Baumann, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-08-09 | Release date: | 2010-10-06 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of a pyridine nucleotide-disulfide family oxidoreductase from the Enterococcus faecalis V583 To be Published
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1T2J
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8Q00
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![BU of 8q00 by Molmil](/molmil-images/mine/8q00) | TssM-Ub-PA complex - A USP-like DUB from B. pseudomallei (193-430) reacted with Ub-PA | Descriptor: | 1,2-ETHANEDIOL, CITRATE ANION, Polyubiquitin-B, ... | Authors: | Uthoff, M, Hermanns, T, Hofmann, K, Baumann, U. | Deposit date: | 2023-07-27 | Release date: | 2023-12-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | The structural basis for deubiquitination by the fingerless USP-type effector TssM. Life Sci Alliance, 7, 2024
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8ADB
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![BU of 8adb by Molmil](/molmil-images/mine/8adb) | Viral tegument-like DUBs | Descriptor: | CITRIC ACID, Polyubiquitin-C, Wc-VDT1, ... | Authors: | Erven, I, Abraham, E.T, Hermanns, T, Baumann, U, Hofmann, K. | Deposit date: | 2022-07-08 | Release date: | 2023-02-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins. Nat Commun, 13, 2022
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8ADC
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![BU of 8adc by Molmil](/molmil-images/mine/8adc) | Viral tegument-like DUBs | Descriptor: | Viral deubiquitinating enzyme | Authors: | Erven, I, Abraham, E.T, Hermanns, T, Baumann, U, Hofmann, K. | Deposit date: | 2022-07-08 | Release date: | 2023-02-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins. Nat Commun, 13, 2022
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1E4R
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![BU of 1e4r by Molmil](/molmil-images/mine/1e4r) | Solution structure of the mouse defensin mBD-8 | Descriptor: | Beta-defensin 8 | Authors: | Bauer, F, Schweimer, K, Kluver, E, Adermann, K, Forssmann, W.G, Roesch, P, Sticht, H. | Deposit date: | 2000-07-12 | Release date: | 2001-07-12 | Last modified: | 2018-06-20 | Method: | SOLUTION NMR | Cite: | Structure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity. Protein Sci., 10, 2001
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6QL9
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![BU of 6ql9 by Molmil](/molmil-images/mine/6ql9) | Structure of Fatty acid synthase complex from Saccharomyces cerevisiae at 2.9 Angstrom | Descriptor: | 1,2-ETHANEDIOL, 4'-PHOSPHOPANTETHEINE, ACETATE ION, ... | Authors: | Singh, K, Graf, B, Linden, A, Sautner, V, Urlaub, H, Tittmann, K, Stark, H, Chari, A. | Deposit date: | 2019-01-31 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase. Cell, 180, 2020
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6HAF
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![BU of 6haf by Molmil](/molmil-images/mine/6haf) | Pyruvate oxidase variant E59Q from L. plantarum in complex with phosphate | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Funk, L.M, Sautner, V, Tittmann, K. | Deposit date: | 2018-08-07 | Release date: | 2019-08-21 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Low-barrier hydrogen bonds in enzyme cooperativity. Nature, 573, 2019
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1Q7X
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![BU of 1q7x by Molmil](/molmil-images/mine/1q7x) | Solution structure of the alternatively spliced PDZ2 domain (PDZ2b) of PTP-Bas (hPTP1E) | Descriptor: | PDZ2b domain of PTP-Bas (hPTP1E) | Authors: | Kachel, N, Erdmann, K.S, Kremer, W, Wolff, P, Gronwald, W, Heumann, R, Kalbitzer, H.R, Structural Proteomics in Europe (SPINE) | Deposit date: | 2003-08-20 | Release date: | 2003-12-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure determination and ligand interactions of the PDZ2b domain of PTP-Bas (hPTP1E): Splicing induced modulation of ligand specificity. J.Mol.Biol., 334, 2003
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1H4B
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![BU of 1h4b by Molmil](/molmil-images/mine/1h4b) | SOLUTION STRUCTURE OF THE BIRCH POLLEN ALLERGEN BET V 4 | Descriptor: | CALCIUM ION, POLCALCIN BET V 4 | Authors: | Neudecker, P, Nerkamp, J, Eisenmann, A, Lauber, T, Lehmann, K, Schweimer, K, Roesch, P. | Deposit date: | 2003-02-26 | Release date: | 2004-02-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure, Dynamics, and Hydrodynamics of the Calcium-Bound Cross-Reactive Birch Pollen Allergen Bet V 4 Reveal a Canonical Monomeric Two EF-Hand Assembly with a Regulatory Function J.Mol.Biol., 336, 2004
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6HIJ
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![BU of 6hij by Molmil](/molmil-images/mine/6hij) | Cryo-EM structure of the human ABCG2-MZ29-Fab complex with cholesterol and PE lipids docked | Descriptor: | 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, ATP-binding cassette sub-family G member 2, CHOLESTEROL, ... | Authors: | Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Taylor, N.M.I, Bause, M, Bauer, S, Bartholomaeus, R, Stahlberg, H, Bernhardt, G, Koenig, B, Buschauer, A, Altmann, K.H, Locher, K.P. | Deposit date: | 2018-08-30 | Release date: | 2018-09-19 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.56 Å) | Cite: | Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nat.Struct.Mol.Biol., 25, 2018
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8PZ3
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1E4Q
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![BU of 1e4q by Molmil](/molmil-images/mine/1e4q) | Solution structure of the human defensin hBD-2 | Descriptor: | BETA-DEFENSIN 2 | Authors: | Bauer, F, Schweimer, K, Kluver, E, Adermann, K, Forssmann, W.G, Roesch, P, Sticht, H. | Deposit date: | 2000-07-12 | Release date: | 2001-07-12 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Structure Determination of Human and Murine Beta-Defensins Reveals Structural Conservation in the Absence of Significant Sequence Similarity Protein Sci., 10, 2001
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