3IOG

Crystal structure of CphA N220G mutant with inhibitor 18

Summary for 3IOG

Entry DOI	10.2210/pdb3iog/pdb
Related	1x8g 1x8h 1x8i 3F9O 3FAI 3IOF
Descriptor	Beta-lactamase, ZINC ION, GLYCEROL, ... (6 entities in total)
Functional Keywords	hydrolase, antibiotic resistance, metal-binding
Biological source	Aeromonas hydrophila
Cellular location	Periplasm (Probable): P26918
Total number of polymer chains	1
Total formula weight	26166.75
Authors	Delbruck, H.,Bebrone, C.,Hoffmann, K.M.V. (deposition date: 2009-08-14, release date: 2010-06-23, Last modification date: 2023-11-01)
Primary citation	Lassaux, P.,Hamel, M.,Gulea, M.,Delbruck, H.,Mercuri, P.S.,Horsfall, L.,Dehareng, D.,Kupper, M.,Frere, J.-M.,Hoffmann, K.,Galleni, M.,Bebrone, C. Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-beta-lactamases J.Med.Chem., 53:4862-4876, 2010 Cited by PubMed: 20527888 DOI: 10.1021/jm100213c PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.41 Å)

Structure validation