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3IOF

Crystal structure of CphA N220G mutant with inhibitor 10a

Summary for 3IOF
Entry DOI10.2210/pdb3iof/pdb
Related1X8G 1x8h 1x8i 3F9O 3FAI 3IOG
DescriptorBeta-lactamase, ZINC ION, bis(1-methylethyl) [2-(sulfanylmethyl)phenyl]phosphonate, ... (6 entities in total)
Functional Keywordshydrolase, antibiotic resistance, metal-binding
Biological sourceAeromonas hydrophila
Cellular locationPeriplasm : P26918
Total number of polymer chains1
Total formula weight26754.43
Authors
Delbruck, H.,Bebrone, C.,Hoffmann, K.M.V. (deposition date: 2009-08-14, release date: 2010-06-23, Last modification date: 2023-11-01)
Primary citationLassaux, P.,Hamel, M.,Gulea, M.,Delbruck, H.,Mercuri, P.S.,Horsfall, L.,Dehareng, D.,Kupper, M.,Frere, J.-M.,Hoffmann, K.,Galleni, M.,Bebrone, C.
Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-beta-lactamases
J.Med.Chem., 53:4862-4876, 2010
Cited by
PubMed: 20527888
DOI: 10.1021/jm100213c
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.44 Å)
Structure validation

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