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PDB: 2589 件

290D
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CRYSTAL STRUCTURES OF OLIGODEOXYRIBONUCLEOTIDES CONTAINING 6'-ALPHA-METHYL AND 6'-ALPHA-HYDROXY CARBOCYCLIC THYMIDINES
分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*(T32)P*(T32)P*CP*GP*CP*G)-3')
著者Portmann, S, Altmann, K.-H, Reynes, N, Egli, M.
登録日1996-10-10
公開日1996-11-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structures of Oligodeoxyribonucleotides Containing 6'-alpha-Methyl and 6'-alpha-Hydroxy Carbocyclic Thymidines
J.Am.Chem.Soc., 119, 1997
291D
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CRYSTAL STRUCTURES OF OLIGODEOXYRIBONUCLEOTIDES CONTAINING 6'-ALPHA-METHYL AND 6'-ALPHA-HYDROXY CARBOCYCLIC THYMIDINES
分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*(T48)P*(T48)P*CP*GP*CP*G)-3'), MAGNESIUM ION
著者Portmann, S, Altmann, K.-H, Reynes, N, Egli, M.
登録日1996-10-10
公開日1996-11-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Crystal Structures of Oligodeoxyribonucleotides Containing 6'-alpha-Methyl and 6'-alpha-Hydroxy Carbocyclic Thymidines
J.Am.Chem.Soc., 119, 1997
248D
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CRYSTAL STRUCTURES OF AN A-FORM DUPLEX WITH SINGLE-ADENOSINE BULGES AND A CONFORMATIONAL BASIS FOR SITE SPECIFIC RNA SELF-CLEAVAGE
分子名称: DNA/RNA (5'-R(*GP*CP*GP*)-D(*AP*TP*AP*TP*AP*)-R(*CP*GP*C)-3'), ORTHORHOMBIC, SPERMINE
著者Portmann, S, Grimm, S, Workman, C, Usman, N, Egli, M.
登録日1996-02-02
公開日1996-03-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Crystal structures of an A-form duplex with single-adenosine bulges and a conformational basis for site-specific RNA self-cleavage.
Chem.Biol., 3, 1996
7KQY
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Crystal Structure and Characterization of Human Heavy-Chain only Antibodies reveals a novel, stable dimeric structure similar to Monoclonal Antibodies
分子名称: Heavy-Chain only Human Antibodies
著者Bahmanjah, S, Mieczkowski, C, Yu, Y, Baker, J, Raghunathan, G, Tomazela, D, Hsieh, M, Mccoy, M, Strickland, C, Fayadat-Dilman, L.
登録日2020-11-18
公開日2020-12-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.913 Å)
主引用文献Crystal Structure and Characterization of Human Heavy-Chain Only Antibodies Reveals a Novel, Stable Dimeric Structure Similar to Monoclonal Antibodies.
Antibodies, 9, 2020
3GTT
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Mouse SOD1
分子名称: Superoxide dismutase [Cu-Zn], ZINC ION
著者Seetharaman, S.V, Taylor, A.B, Hart, P.J.
登録日2009-03-28
公開日2010-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of mouse SOD1 and human/mouse SOD1 chimeras.
Arch.Biochem.Biophys., 503, 2010
3H2P
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Human SOD1 D124V Variant
分子名称: ACETYL GROUP, MALONATE ION, Superoxide dismutase [Cu-Zn], ...
著者Seetharaman, S.V, Winkler, D.D, Taylor, A.B, Cao, X, Whitson, L.J, Doucette, P.A, Valentine, J.S, Carroll, M.C, Culotta, V.C, Hart, P.J.
登録日2009-04-14
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding and Compromised Post-translational Modification by the Copper Chaperone CCS
To be Published
3GTV
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Human-mouse SOD1 chimera
分子名称: Superoxide dismutase [Cu-Zn], ZINC ION
著者Seetharaman, S.V, Taylor, A.B, Hart, P.J.
登録日2009-03-28
公開日2010-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of mouse SOD1 and human/mouse SOD1 chimeras.
Arch.Biochem.Biophys., 503, 2010
7JRQ
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Crystallographically Characterized De Novo Designed Mn-Diphenylporphyrin Binding Protein
分子名称: CHLORIDE ION, GLYCEROL, MPP1, ...
著者Mann, S.I, DeGrado, W.F.
登録日2020-08-12
公開日2021-01-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献De Novo Design, Solution Characterization, and Crystallographic Structure of an Abiological Mn-Porphyrin-Binding Protein Capable of Stabilizing a Mn(V) Species.
J.Am.Chem.Soc., 143, 2021
3H2Q
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Human SOD1 H80R variant, P21 crystal form
分子名称: SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Seetharaman, S.V, Winkler, D.D, Taylor, A.B, Cao, X, Whitson, L.J, Doucette, P.A, Valentine, J.S, Carroll, M.C, Culotta, V.C, Hart, P.J.
登録日2009-04-14
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding and Compromised Post-translational Modification by the Copper Chaperone CCS
To be Published
3C0K
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Crystal Structure of a ribosomal RNA methyltranferase
分子名称: UPF0064 protein yccW
著者Subramanian, S, Jayaraman, S, Bujnicki, J.
登録日2008-01-21
公開日2008-11-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the Escherichia coli 23S rRNA:m5C methyltransferase RlmI (YccW) reveals evolutionary links between RNA modification enzymes
J.Mol.Biol., 383, 2008
7KZF
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BU of 7kzf by Molmil
High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility
分子名称: Major capsid protein L1
著者Hartmann, S.R, Goetschius, D.J, Hafenstein, S.
登録日2020-12-10
公開日2021-02-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility.
Sci Rep, 11, 2021
7JLR
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Crystal structure of Bacillus subtilis UppS in complex with JPD447
分子名称: 7-(azepan-1-yl)-5-ethyl-3-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine, Isoprenyl transferase
著者Workman, S.D, Strynadka, N.C.J.
登録日2020-07-30
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria.
J.Med.Chem., 64, 2021
7JLI
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Crystal structure of Bacillus subtilis UppS
分子名称: DI(HYDROXYETHYL)ETHER, Isoprenyl transferase
著者Workman, S.D, Strynadka, N.C.J.
登録日2020-07-29
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria.
J.Med.Chem., 64, 2021
7JLM
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Crystal structure of Bacillus subtilis UppS in complex with MAC-0547630
分子名称: 7-(azepan-1-yl)-3-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidine, CITRIC ACID, Isoprenyl transferase
著者Workman, S.D, Strynadka, N.C.J.
登録日2020-07-29
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria.
J.Med.Chem., 64, 2021
7JLJ
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Crystal structure of Bacillus subtilis UppS in complex with clomiphene
分子名称: Clomifene, Isoprenyl transferase
著者Workman, S.D, Strynadka, N.C.J.
登録日2020-07-29
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria.
J.Med.Chem., 64, 2021
5SVR
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BU of 5svr by Molmil
Crystal structure of the ATP-gated human P2X3 ion channel bound to competitive antagonist A-317491
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-{[(3-phenoxyphenyl)methyl][(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl}benzene-1,2,4-tricarboxylic acid, MAGNESIUM ION, ...
著者Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E.
登録日2016-08-07
公開日2016-10-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVJ
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Crystal structure of the ATP-gated human P2X3 ion channel in the closed, apo state
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ...
著者Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E.
登録日2016-08-06
公開日2016-09-28
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.984 Å)
主引用文献X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVQ
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Crystal structure of the ATP-gated human P2X3 ion channel bound to competitive antagonist TNP-ATP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, P2X purinoceptor 3, ...
著者Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E.
登録日2016-08-07
公開日2016-10-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVT
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Anomalous Cs+ signal reveals the site of Na+ ion entry to the channel pore of the human P2X3 ion channel through the extracellular fenestrations
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, P2X purinoceptor 3, ...
著者Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E.
登録日2016-08-07
公開日2016-09-28
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.794 Å)
主引用文献X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVS
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Anomalous Mn2+ signal reveals a divalent cation-binding site in the head domain of the ATP-gated human P2X3 ion channel
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ...
著者Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E.
登録日2016-08-07
公開日2016-09-28
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (4.025 Å)
主引用文献X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
4BD0
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X-ray structure of a perdeuterated Toho-1 R274N R276N double mutant Beta-lactamase in complex with a fully deuterated boronic acid (BZB)
分子名称: BENZO[B]THIOPHENE-2-BORONIC ACID, BETA-LACTAMASE TOHO-1, SULFATE ION
著者Tomanicek, S.J, Weiss, K.L, Standaert, R.F, Ostermann, A, Schrader, T.E, Ng, J.D, Coates, L.
登録日2012-10-04
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.207 Å)
主引用文献Neutron and X-Ray Crystal Structures of a Perdeuterated Enzyme Inhibitor Complex Reveal the Catalytic Proton Network of the Toho-1 Beta-Lactamase for the Acylation Reaction.
J.Biol.Chem., 288, 2013
4BD1
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Neutron structure of a perdeuterated Toho-1 R274N R276N double mutant Beta-lactamase in complex with a fully deuterated boronic acid (BZB)
分子名称: BENZO[B]THIOPHENE-2-BORONIC ACID, TOHO-1 BETA-LACTAMASE
著者Tomanicek, S.J, Weiss, K.L, Standaert, R.F, Ostermann, A, Schrader, T.E, Ng, J.D, Coates, L.
登録日2012-10-04
公開日2013-01-16
最終更新日2017-03-22
実験手法NEUTRON DIFFRACTION (2.002 Å)
主引用文献Neutron and X-Ray Crystal Structures of a Perdeuterated Enzyme Inhibitor Complex Reveal the Catalytic Proton Network of the Toho-1 Beta-Lactamase for the Acylation Reaction.
J.Biol.Chem., 288, 2013
4BPF
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High resolution crystal structure of Bacillus subtilis DltC S36A
分子名称: D-ALANINE--POLY(PHOSPHORIBITOL) LIGASE SUBUNIT 2
著者Zimmermann, S, Neumann, P, Stubbs, M.T.
登録日2013-05-26
公開日2014-06-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.01 Å)
主引用文献High-Resolution Structures of the D-Alanyl Carrier Protein (Dcp) Dltc from Bacillus Subtilis Reveal Equivalent Conformations of Apo- and Holo-Forms
FEBS Lett., 589, 2015
4BPH
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High resolution crystal structure of Bacillus subtilis DltC
分子名称: 4'-PHOSPHOPANTETHEINE, D-ALANINE--POLY(PHOSPHORIBITOL) LIGASE SUBUNIT 2, MAGNESIUM ION
著者Zimmermann, S, Neumann, P, Stubbs, M.T.
登録日2013-05-26
公開日2014-06-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High-Resolution Structures of the D-Alanyl Carrier Protein (Dcp) Dltc from Bacillus Subtilis Reveal Equivalent Conformations of Apo- and Holo-Forms
FEBS Lett., 589, 2015
5SVM
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BU of 5svm by Molmil
Crystal structure of the ATP-gated human P2X3 ion channel bound to agonist 2-methylthio-ATP in the desensitized state
分子名称: 1,2-ETHANEDIOL, 2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate), 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E.
登録日2016-08-06
公開日2016-09-28
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.093 Å)
主引用文献X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016

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