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PDB: 45 件
3Q7C
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BU of 3q7c by Molmil
Exonuclease domain of Lassa virus nucleoprotein bound to manganese
分子名称: MANGANESE (II) ION, Nucleoprotein, PHOSPHATE ION, ...
著者Hastie, K.M, Kimberlin, C.R, Zandonatti, M.A, MacRae, I.J, Saphire, E.O.
登録日2011-01-04
公開日2011-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression.
Proc.Natl.Acad.Sci.USA, 108, 2011
3Q7B
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BU of 3q7b by Molmil
Exonuclease domain of Lassa virus nucleoprotein
分子名称: Nucleoprotein, PHOSPHATE ION, ZINC ION
著者Hastie, K.M, Kimberlin, C.R, Zandonatti, M.A, MacRae, I.J, Saphire, E.O.
登録日2011-01-04
公開日2011-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression.
Proc.Natl.Acad.Sci.USA, 108, 2011
6BJG
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BU of 6bjg by Molmil
CIRV p19 mutant T111H in complex with siRNA
分子名称: RNA (5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*AP*UP*U)-3'), RNA (5'-R(P*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*GP*UP*U)-3'), RNA silencing suppressor p19
著者Foss, D.V, Schirle, N, Pezacki, J.P, Macrae, I.J.
登録日2017-11-06
公開日2019-01-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs.
Febs Open Bio, 9, 2019
6BJH
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BU of 6bjh by Molmil
CIRV p19 mutant T111S in complex with siRNA
分子名称: RNA (5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*AP*UP*U)-3'), RNA (5'-R(P*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*GP*UP*U)-3'), RNA silencing suppressor p19
著者Foss, D.V, Schirle, N.T, MacRae, I.J, Pezacki, J.P.
登録日2017-11-06
公開日2019-01-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs.
Febs Open Bio, 9, 2019
6CBD
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BU of 6cbd by Molmil
Crystal Structure of Human Argonaute2 Bound to Three Tryptophans
分子名称: Guide RNA, ISOPROPYL ALCOHOL, MAGNESIUM ION, ...
著者Sheu-Gruttadauria, J, MacRae, I.J.
登録日2018-02-02
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.203 Å)
主引用文献Phase Transitions in the Assembly and Function of Human miRISC.
Cell, 173, 2018
6BJV
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BU of 6bjv by Molmil
CIRV p19 protein in complex with siRNA
分子名称: RNA (5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*AP*UP*U)-3'), RNA (5'-R(P*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*GP*UP*U)-3'), RNA silencing suppressor p19
著者Foss, D.V, Schirle, N, Pezacki, J.P, Macrae, I.J.
登録日2017-11-07
公開日2019-01-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.198 Å)
主引用文献Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs.
Febs Open Bio, 9, 2019
4Z4F
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BU of 4z4f by Molmil
Human Argonaute2 Bound to t1-DAP Target RNA
分子名称: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
著者Schirle, N.T, MacRae, I.J.
登録日2015-04-02
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4D
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BU of 4z4d by Molmil
Human Argonaute2 Bound to t1-G Target RNA
分子名称: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
著者Schirle, N.T, MacRae, I.J.
登録日2015-04-02
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4C
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BU of 4z4c by Molmil
Human Argonaute2 Bound to t1-C Target RNA
分子名称: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
著者Schirle, N.T, MacRae, I.J.
登録日2015-04-02
公開日2015-09-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4H
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BU of 4z4h by Molmil
Human Argonaute2 A481T Mutant Bound to t1-A Target RNA
分子名称: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
著者Schirle, N.T, MacRae, I.J.
登録日2015-04-02
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.504 Å)
主引用文献Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4I
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BU of 4z4i by Molmil
Human Argonaute2 A481T Mutant Bound to t1-G Target RNA
分子名称: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
著者Schirle, N.T, MacRae, I.J.
登録日2015-04-02
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4E
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BU of 4z4e by Molmil
Human Argonaute2 Bound to t1-U Target RNA
分子名称: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
著者Schirle, N.T, MacRae, I.J.
登録日2015-04-02
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4G
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BU of 4z4g by Molmil
Human Argonaute2 Bound to t1-Inosine Target RNA
分子名称: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
著者Schirle, N.T, MacRae, I.J.
登録日2015-04-02
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
6MFR
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BU of 6mfr by Molmil
Human Argonaute2-miR-122 bound to a target RNA with three central mismatches (bu3)
分子名称: PHENOL, PHOSPHATE ION, Protein argonaute-2, ...
著者Sheu-Gruttadauria, J, MacRae, I.J.
登録日2018-09-12
公開日2019-08-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
6MFN
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BU of 6mfn by Molmil
Human Argonaute2-miR-27a bound to HSUR1 target RNA
分子名称: PHENOL, Protein argonaute-2, RNA (5'-R(P*UP*CP*UP*GP*UP*GP*AP*UP*AP*A)-3'), ...
著者Sheu-Gruttadauria, J, MacRae, I.J.
登録日2018-09-11
公開日2019-08-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
6N4O
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BU of 6n4o by Molmil
Human Argonaute2-miR-122 bound to a seed and supplementary paired target
分子名称: Protein argonaute-2, RNA (5'-R(*CP*CP*AP*UP*UP*GP*UP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3')
著者Sheu-Gruttadauria, J, MacRae, I.J.
登録日2018-11-19
公開日2019-05-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.899 Å)
主引用文献Beyond the seed: structural basis for supplementary microRNA targeting by human Argonaute2.
Embo J., 38, 2019
6NIT
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BU of 6nit by Molmil
Human Argonaute2-miR-122 bound to a target RNA with four central mismatches (bu4)
分子名称: Protein argonaute-2, RNA (5'-R(P*AP*AP*CP*AP*CP*CP*AP*UP*CP*CP*AP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3')
著者Sheu-Gruttadauria, J, MacRae, I.J.
登録日2018-12-31
公開日2019-08-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
6MDZ
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BU of 6mdz by Molmil
Human Argonaute2-miR-122 bound to a target RNA with two central mismatches (bu2)
分子名称: PHENOL, Protein argonaute-2, RNA (5'-R(P*AP*AP*AP*CP*AP*CP*CP*AP*UP*UP*UP*CP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), ...
著者Sheu-Gruttadauria, J, MacRae, I.J.
登録日2018-09-05
公開日2019-08-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
2FFL
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BU of 2ffl by Molmil
Crystal Structure of Dicer from Giardia intestinalis
分子名称: Dicer, MANGANESE (II) ION
著者Doudna, J.A, MacRae, I.J, Adams, P.D.
登録日2005-12-19
公開日2006-01-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.33 Å)
主引用文献Structural Basis of Double-Stranded RNA Processing by Dicer
Science, 311, 2006
1JHD
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BU of 1jhd by Molmil
Crystal Structure of Bacterial ATP Sulfurylase from the Riftia pachyptila Symbiont
分子名称: BROMIDE ION, SULFATE ADENYLYLTRANSFERASE, SULFATE ION
著者Beynon, J.D, MacRae, I.J, Huston, S.L, Nelson, D.C, Segel, I.H, Fisher, A.J.
登録日2001-06-27
公開日2001-12-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of ATP sulfurylase from the bacterial symbiont of the hydrothermal vent tubeworm Riftia pachyptila.
Biochemistry, 40, 2001
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