5NRY
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![BU of 5nry by Molmil](/molmil-images/mine/5nry) | Cys-Gly dipeptidase GliJ in complex with Fe3+ | Descriptor: | CHLORIDE ION, Dipeptidase gliJ, FE (III) ION | Authors: | Groll, M, Huber, E.M. | Deposit date: | 2017-04-25 | Release date: | 2017-05-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Gliotoxin Biosynthesis: Structure, Mechanism, and Metal Promiscuity of Carboxypeptidase GliJ. ACS Chem. Biol., 12, 2017
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5TF1
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![BU of 5tf1 by Molmil](/molmil-images/mine/5tf1) | Structure of chimeric 02-CC Fab, a VRC01-like germline antibody | Descriptor: | 02-CC Fab Heavy chain, O2-CC Fab Light Chain | Authors: | Pancera, M. | Deposit date: | 2016-09-23 | Release date: | 2016-11-16 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (1.858 Å) | Cite: | Differences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors. Cell Rep, 17, 2016
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3OZT
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![BU of 3ozt by Molmil](/molmil-images/mine/3ozt) | Rat catechol O-methyltransferase in complex with a catechol-type, 4-oxo-pyridinyl-containing inhibitor - humanized form | Descriptor: | Catechol O-methyltransferase, MAGNESIUM ION, N-[(E)-3-[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-oxopyridin-1-yl)oxolan-2-yl]prop-2-enyl]-2,3-dihydroxy-5-nitro-benzamide | Authors: | Ehler, A, Schlatter, D, Stihle, M, Benz, J, Rudolph, M.G. | Deposit date: | 2010-09-27 | Release date: | 2011-03-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Molecular Recognition at the Active Site of Catechol-O-methyltransferase (COMT): Adenine Replacements in Bisubstrate Inhibitors Chemistry, 17, 2011
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5TFZ
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5J60
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![BU of 5j60 by Molmil](/molmil-images/mine/5j60) | Structure of a thioredoxin reductase from Gloeobacter violaceus | Descriptor: | CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, TETRAETHYLENE GLYCOL, ... | Authors: | Buey, R.M, de Pereda, J.M, Balsera, M. | Deposit date: | 2016-04-04 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A New Member of the Thioredoxin Reductase Family from Early Oxygenic Photosynthetic Organisms. Mol Plant, 10, 2017
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5AQD
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![BU of 5aqd by Molmil](/molmil-images/mine/5aqd) | Crystal structure of Phormidium Phycoerythrin at pH 8.5 | Descriptor: | GLYCEROL, PHYCOERYTHRIN ALPHA SUBUNIT, PHYCOERYTHRIN BETA SUBUNIT, ... | Authors: | Kumar, V, Sharma, M, Sonani, R.R, Gupta, G.D, Madamwar, D. | Deposit date: | 2015-09-22 | Release date: | 2016-06-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.121 Å) | Cite: | Crystal Structure Analysis of C-Phycoerythrin from Marine Cyanobacterium Phormidium Sp. A09Dm. Photosynth.Res., 129, 2016
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3BKC
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![BU of 3bkc by Molmil](/molmil-images/mine/3bkc) | Crystal structure of anti-amyloid beta FAB WO2 (P21, FormB) | Descriptor: | SODIUM ION, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa | Authors: | Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W. | Deposit date: | 2007-12-06 | Release date: | 2008-04-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J.Mol.Biol., 377, 2008
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5TGZ
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![BU of 5tgz by Molmil](/molmil-images/mine/5tgz) | Crystal Structure of the Human Cannabinoid Receptor CB1 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-[4-[2-(2,4-dichlorophenyl)-4-methyl-5-(piperidin-1-ylcarbamoyl)pyrazol-3-yl]phenyl]but-3-ynyl nitrate, Cannabinoid receptor 1,Flavodoxin,Cannabinoid receptor 1, ... | Authors: | Hua, T, Vemuri, K, Pu, M, Qu, L, Han, G.W, Wu, Y, Zhao, S, Shui, W, Li, S, Korde, A, Laprairie, R.B, Stahl, E.L, Ho, J.H, Zvonok, N, Zhou, H, Kufareva, I, Wu, B, Zhao, Q, Hanson, M.A, Bohn, L.M, Makriyannis, A, Stevens, R.C, Liu, Z.J. | Deposit date: | 2016-09-28 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of the Human Cannabinoid Receptor CB1. Cell, 167, 2016
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1D3Z
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![BU of 1d3z by Molmil](/molmil-images/mine/1d3z) | UBIQUITIN NMR STRUCTURE | Descriptor: | PROTEIN (UBIQUITIN) | Authors: | Cornilescu, G, Marquardt, J.L, Ottiger, M, Bax, A. | Deposit date: | 1999-10-01 | Release date: | 1999-10-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Validation of Protein Structure from Anisotropic Carbonyl Chemical Shifts in a Dilute Liquid Crystalline Phase J.Am.Chem.Soc., 120, 1998
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1LQQ
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![BU of 1lqq by Molmil](/molmil-images/mine/1lqq) | ANTI-MAMMAL AND ANTI-INSECT LQQIII SCORPION TOXIN, NMR, 15 STRUCTURES | Descriptor: | LQQIII | Authors: | Landon, C, Sodano, P, Vovelle, F, Ptak, M. | Deposit date: | 1997-05-18 | Release date: | 1998-05-20 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | 1H-NMR-derived secondary structure and the overall fold of the potent anti-mammal and anti-insect toxin III from the scorpion Leiurus quinquestriatus quinquestriatus. Eur.J.Biochem., 236, 1996
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5JJF
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![BU of 5jjf by Molmil](/molmil-images/mine/5jjf) | Structure of the SRII/HtrII Complex in I212121 space group ("U" shape) - M state | Descriptor: | EICOSANE, RETINAL, Sensory rhodopsin II transducer, ... | Authors: | Ishchenko, A, Round, E, Borshchevskiy, V, Grudinin, S, Gushchin, I, Klare, J, Remeeva, A, Polovinkin, V, Utrobin, P, Balandin, T, Engelhard, M, Bueldt, G, Gordeliy, V. | Deposit date: | 2016-04-23 | Release date: | 2017-02-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | New Insights on Signal Propagation by Sensory Rhodopsin II/Transducer Complex. Sci Rep, 7, 2017
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5THL
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5JLS
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5DKJ
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![BU of 5dkj by Molmil](/molmil-images/mine/5dkj) | Yeast 20S proteasome in complex with octreotide-PI | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... | Authors: | Beck, P, Cui, H, Groll, M. | Deposit date: | 2015-09-03 | Release date: | 2015-10-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Targeted Delivery of Proteasome Inhibitors to Somatostatin-Receptor-Expressing Cancer Cells by Octreotide Conjugation. Chemmedchem, 10, 2015
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1AG2
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![BU of 1ag2 by Molmil](/molmil-images/mine/1ag2) | PRION PROTEIN DOMAIN PRP(121-231) FROM MOUSE, NMR, 2 MINIMIZED AVERAGE STRUCTURE | Descriptor: | MAJOR PRION PROTEIN | Authors: | Billeter, M, Riek, R, Wider, G, Wuthrich, K, Hornemann, S, Glockshuber, R. | Deposit date: | 1997-03-31 | Release date: | 1997-10-08 | Last modified: | 2024-06-05 | Method: | SOLUTION NMR | Cite: | NMR structure of the mouse prion protein domain PrP(121-231). Nature, 382, 1996
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5TNZ
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![BU of 5tnz by Molmil](/molmil-images/mine/5tnz) | HtrA2 S142D mutant | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SODIUM ION, Serine protease HTRA2, ... | Authors: | Macedo-Ribeiro, S, Merski, M, Pereira, P.J.B. | Deposit date: | 2016-10-15 | Release date: | 2017-10-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2. Cell Death Dis, 8, 2017
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5DNV
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![BU of 5dnv by Molmil](/molmil-images/mine/5dnv) | Crystal structure of KAI2-like protein from Striga (apo state 2) | Descriptor: | BENZOIC ACID, FORMIC ACID, ShKAI2iB | Authors: | Xu, Y, Miyakawa, T, Nakamura, A, Tanokura, M. | Deposit date: | 2015-09-10 | Release date: | 2016-08-17 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural basis of unique ligand specificity of KAI2-like protein from parasitic weed Striga hermonthica Sci Rep, 6, 2016
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8E51
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![BU of 8e51 by Molmil](/molmil-images/mine/8e51) | Crystal Structure of Iridescent Shark Catfish Cadherin-23 EC1-2 and Protocadherin-15 EC1-2 | Descriptor: | CALCIUM ION, Cadherin-23, POTASSIUM ION, ... | Authors: | Scheib, E, Nisler, C.R, Sotomayor, M. | Deposit date: | 2022-08-19 | Release date: | 2023-03-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.594 Å) | Cite: | Interpreting the Evolutionary Echoes of a Protein Complex Essential for Inner-Ear Mechanosensation. Mol.Biol.Evol., 40, 2023
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5DQI
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![BU of 5dqi by Molmil](/molmil-images/mine/5dqi) | Crystal Structure of Human DNA Polymerase Eta Extending an O4-Ethylthymidine : dA Pair By Inserting dCTP Opposite dG | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*AP*C)-3'), ... | Authors: | Patra, A, OFlaherty, D.K, Egli, M. | Deposit date: | 2015-09-14 | Release date: | 2016-08-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta. Chem Sci, 7, 2016
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6H4A
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![BU of 6h4a by Molmil](/molmil-images/mine/6h4a) | Human MALT1(329-728) in complex with MLT-748 | Descriptor: | 1-[2-chloranyl-7-[(1~{R},2~{R})-1,2-dimethoxypropyl]pyrazolo[1,5-a]pyrimidin-6-yl]-3-[5-chloranyl-6-(1,2,3-triazol-2-yl)pyridin-3-yl]urea, Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | Authors: | Renatus, M, Renatus, M. | Deposit date: | 2018-07-20 | Release date: | 2019-02-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient. Nat. Chem. Biol., 15, 2019
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5KHU
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![BU of 5khu by Molmil](/molmil-images/mine/5khu) | Model of human Anaphase-promoting complex/Cyclosome (APC15 deletion mutant), in complex with the Mitotic checkpoint complex (APC/C-CDC20-MCC) based on cryo EM data at 4.8 Angstrom resolution | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | Authors: | Yamaguchi, M, VanderLinden, R, Dube, P, Stark, H, Schulman, B. | Deposit date: | 2016-06-15 | Release date: | 2016-09-07 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation. Mol.Cell, 63, 2016
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4L8Z
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![BU of 4l8z by Molmil](/molmil-images/mine/4l8z) | Crystal structure of Human Hsp90 with RL1 | Descriptor: | Heat shock protein HSP 90-alpha, [5-(6-bromo[1,2,4]triazolo[4,3-a]pyridin-3-yl)-2,4-dihydroxyphenyl](3,4-dihydroisoquinolin-2(1H)-yl)methanone | Authors: | Li, J, Ren, J, Yang, M, Xiong, B, He, J. | Deposit date: | 2013-06-18 | Release date: | 2014-06-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.703 Å) | Cite: | Identification of a new series of potent diphenol HSP90 inhibitors by fragment merging and structure-based optimization Bioorg.Med.Chem.Lett., 24, 2014
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5DRZ
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![BU of 5drz by Molmil](/molmil-images/mine/5drz) | Crystal structure of anti-HIV-1 antibody F240 Fab in complex with gp41 peptide | Descriptor: | Envelope glycoprotein gp160, HIV Antibody F240 Heavy Chain, HIV Antibody F240 Light Chain, ... | Authors: | Gohain, N, Tolbert, W.D, Pazgier, M. | Deposit date: | 2015-09-16 | Release date: | 2016-10-19 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Molecular basis for epitope recognition by non-neutralizing anti-gp41 antibody F240. Sci Rep, 6, 2016
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3OKV
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![BU of 3okv by Molmil](/molmil-images/mine/3okv) | Human Carbonic Anhydrase II A65S, N67Q (CA IX mimic) bound with 2-Ethylestrone 3-O-sulfamate | Descriptor: | (9beta)-2-ethyl-17-oxoestra-1(10),2,4-trien-3-yl sulfamate, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | Authors: | Sippel, K.H, Stander, B.A, Robbins, A.H, Tu, C.K, Agbandje-McKenna, M, Silverman, D.N, Joubert, A.M, McKenna, R. | Deposit date: | 2010-08-25 | Release date: | 2011-07-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds LETT.DRUG DES.DISCOVERY, 8, 2011
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2NV4
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![BU of 2nv4 by Molmil](/molmil-images/mine/2nv4) | Crystal structure of UPF0066 protein AF0241 in complex with S-adenosylmethionine. Northeast Structural Genomics Consortium target GR27 | Descriptor: | ACETATE ION, S-ADENOSYLMETHIONINE, UPF0066 protein AF_0241 | Authors: | Kuzin, A.P, Abashidze, M, Seetharaman, J, Vorobiev, S.M, Fang, Y, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-11-10 | Release date: | 2006-11-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Functional insights from structural genomics. J.Struct.Funct.Genom., 8, 2007
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