8E51

Crystal Structure of Iridescent Shark Catfish Cadherin-23 EC1-2 and Protocadherin-15 EC1-2

Summary for 8E51

• Entry DOI: 10.2210/pdb8e51/pdb
• Descriptor: Protocadherin-15, Cadherin-23, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: hearing, deafness, cdh23, pcdh15, evolution, tip link, cell adhesion
• Biological source: Pangasianodon hypophthalmus (striped catfish); More
• Total number of polymer chains: 2
• Total formula weight: 53643.82

Authors

Scheib, E.,Nisler, C.R.,Sotomayor, M. (deposition date: 2022-08-19, release date: 2023-03-22, Last modification date: 2024-04-03)

• Primary citation: Nisler, C.R.,Narui, Y.,Scheib, E.,Choudhary, D.,Bowman, J.D.,Mandayam Bharathi, H.,Lynch, V.J.,Sotomayor, M.; Interpreting the Evolutionary Echoes of a Protein Complex Essential for Inner-Ear Mechanosensation.; Mol.Biol.Evol., 40:-, 2023; PubMed: 36911992; DOI: 10.1093/molbev/msad057

Experimental method

X-RAY DIFFRACTION (2.594 Å)