5DRZ

Crystal structure of anti-HIV-1 antibody F240 Fab in complex with gp41 peptide

Summary for 5DRZ

• Entry DOI: 10.2210/pdb5drz/pdb
• Descriptor: HIV Antibody F240 Light Chain, HIV Antibody F240 Heavy Chain, Envelope glycoprotein gp160, ... (5 entities in total)
• Functional Keywords: igg, viral protein, hiv gp41 envelope protein, immune system
• Biological source: Homo sapiens; More
• Cellular location: Surface protein gp120: Virion membrane ; Peripheral membrane protein . Transmembrane protein gp41: Virion membrane ; Single-pass type I membrane protein : P03378
• Total number of polymer chains: 6
• Total formula weight: 106863.35

Authors

Gohain, N.,Tolbert, W.D.,Pazgier, M. (deposition date: 2015-09-16, release date: 2016-10-19, Last modification date: 2023-09-27)

• Primary citation: Gohain, N.,Tolbert, W.D.,Orlandi, C.,Richard, J.,Ding, S.,Chen, X.,Bonsor, D.A.,Sundberg, E.J.,Lu, W.,Ray, K.,Finzi, A.,Lewis, G.K.,Pazgier, M.; Molecular basis for epitope recognition by non-neutralizing anti-gp41 antibody F240.; Sci Rep, 6:36685-36685, 2016; PubMed: 27827447; DOI: 10.1038/srep36685

Experimental method

X-RAY DIFFRACTION (2.54 Å)