5DRZ
Crystal structure of anti-HIV-1 antibody F240 Fab in complex with gp41 peptide
Summary for 5DRZ
Entry DOI | 10.2210/pdb5drz/pdb |
Descriptor | HIV Antibody F240 Light Chain, HIV Antibody F240 Heavy Chain, Envelope glycoprotein gp160, ... (5 entities in total) |
Functional Keywords | igg, viral protein, hiv gp41 envelope protein, immune system |
Biological source | Homo sapiens More |
Cellular location | Surface protein gp120: Virion membrane ; Peripheral membrane protein . Transmembrane protein gp41: Virion membrane ; Single-pass type I membrane protein : P03378 |
Total number of polymer chains | 6 |
Total formula weight | 106863.35 |
Authors | Gohain, N.,Tolbert, W.D.,Pazgier, M. (deposition date: 2015-09-16, release date: 2016-10-19, Last modification date: 2023-09-27) |
Primary citation | Gohain, N.,Tolbert, W.D.,Orlandi, C.,Richard, J.,Ding, S.,Chen, X.,Bonsor, D.A.,Sundberg, E.J.,Lu, W.,Ray, K.,Finzi, A.,Lewis, G.K.,Pazgier, M. Molecular basis for epitope recognition by non-neutralizing anti-gp41 antibody F240. Sci Rep, 6:36685-36685, 2016 Cited by PubMed: 27827447DOI: 10.1038/srep36685 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.54 Å) |
Structure validation
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