5TNZ

HtrA2 S142D mutant

Summary for 5TNZ

Related5m3n 5m3o 5to0 5tny 5to1
DescriptorSerine protease HTRA2, mitochondrial, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SODIUM ION, ... (4 entities in total)
Functional Keywordsmitochondrial protease, serine protease, trimeric dynamics, hydrolase
Biological sourceHomo sapiens (Human)
Cellular locationMitochondrion intermembrane space O43464
Total number of polymer chains1
Total molecular weight36224.13
Authors
Macedo-Ribeiro, S.,Merski, M.,Pereira, P.J.B. (deposition date: 2016-10-15, release date: 2017-10-25)
Primary citation
Merski, M.,Moreira, C.,Abreu, R.M.,Ramos, M.J.,Fernandes, P.A.,Martins, L.M.,Pereira, P.J.B.,Macedo-Ribeiro, S.
Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2.
Cell Death Dis, 8:e3119-e3119, 2017
PubMed: 29022916 (PDB entries with the same primary citation)
DOI: 10.1038/cddis.2017.487
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.75 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.167502.1%2.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report