5TNZ
HtrA2 S142D mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine protease HTRA2, mitochondrial | polymer | 332 | 36005.9 | 1 | UniProt (O43464) Pfam (PF13365) Pfam (PF17820) | Homo sapiens (Human) | High temperature requirement protein A2,HtrA2,Omi stress-regulated endoprotease,Serine protease 25,Serine proteinase OMI |
| 2 | B (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 3 | C (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | D (A) | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A: 134 - 458 (UniProt: O43464)
| PDB | External Database | Details |
|---|---|---|
| Met 133 | - | initiating methionine |
| Asp 142 | Ser 142 | engineered mutation |
| His 459 | - | expression tag |
| His 460 | - | expression tag |
| His 461 | - | expression tag |
| His 462 | - | expression tag |
| His 463 | - | expression tag |
| His 464 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36005.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 218.2 | |
| All* | Total formula weight | 36224.1 |
