1ILE
| ISOLEUCYL-TRNA SYNTHETASE | 分子名称: | ISOLEUCYL-TRNA SYNTHETASE, ZINC ION | 著者 | Nureki, O, Vassylyev, D.G, Tateno, M, Shimada, A, Nakama, T, Fukai, S, Konno, M, Schimmel, P, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 1998-02-24 | 公開日 | 1999-04-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Enzyme structure with two catalytic sites for double-sieve selection of substrate. Science, 280, 1998
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6XER
| Tubulin-RB3_SLD in complex with colchicine | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | White, S.W, Yun, M. | 登録日 | 2020-06-13 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Design, Synthesis, and Biological Evaluation of Stable Colchicine-Binding Site Tubulin Inhibitors 6-Aryl-2-benzoyl-pyridines as Potential Anticancer Agents. J.Med.Chem., 64, 2021
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6XET
| Tubulin-RB3_SLD in complex with compound 60c | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | White, S.W, Yun, M. | 登録日 | 2020-06-13 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Design, Synthesis, and Biological Evaluation of Stable Colchicine-Binding Site Tubulin Inhibitors 6-Aryl-2-benzoyl-pyridines as Potential Anticancer Agents. J.Med.Chem., 64, 2021
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4LZ9
| Structure of MATE multidrug transporter DinF-BH in complex with R6G | 分子名称: | BH2163 protein, RHODAMINE 6G | 著者 | Lu, M, Radchenko, M, Symersky, J, Nie, R, Guo, Y. | 登録日 | 2013-07-31 | 公開日 | 2013-10-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structural insights into H(+)-coupled multidrug extrusion by a MATE transporter Nat.Struct.Mol.Biol., 20, 2013
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6XES
| Tubulin-RB3_SLD in complex with compound 40a | 分子名称: | DIMETHYL SULFOXIDE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | White, S.W, Yun, M. | 登録日 | 2020-06-13 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Design, Synthesis, and Biological Evaluation of Stable Colchicine-Binding Site Tubulin Inhibitors 6-Aryl-2-benzoyl-pyridines as Potential Anticancer Agents. J.Med.Chem., 64, 2021
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1IQY
| CRYSTAL STRUCTURE OF NICKEL-SUBSTITUTED AMINE OXIDASE FROM ARTHROBACTER GLOBIFORMIS | 分子名称: | AMINE OXIDASE, NICKEL (II) ION | 著者 | Kishishita, S, Okajima, T, Mure, M, Kim, M, Yamaguchi, H, Hirota, S, Kuroda, S, Tanizawa, K. | 登録日 | 2001-08-28 | 公開日 | 2003-02-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Role of Copper Ion in Bacterial Copper Amine Oxidase: Spectroscopic and Crystallographic Studies of Metal-Substituted Enzymes J.AM.CHEM.SOC., 125, 2003
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3LM8
| Crystal Structure of Thiamine pyrophosphokinase from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR677 | 分子名称: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Kuzin, A, Abashidze, M, Seetharaman, J, Mao, M, Xiao, R, Foote, E.L, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2010-01-29 | 公開日 | 2010-03-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target SR677 To be Published
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4M0X
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1ITZ
| Maize Transketolase in complex with TPP | 分子名称: | MAGNESIUM ION, THIAMINE DIPHOSPHATE, Transketolase | 著者 | Gerhardt, S, Echt, S, Bader, G, Freigang, J, Busch, M, Bacher, A, Huber, R, Fischer, M. | 登録日 | 2002-02-15 | 公開日 | 2003-02-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure and properties of an engineered transketolase from maize PLANT PHYSIOL., 132, 2003
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6RXJ
| Crystal structure of CobB wt in complex with H4K16-Acetyl peptide | 分子名称: | Histone H4, NAD-dependent protein deacylase, ZINC ION | 著者 | Spinck, M, Gasper, R, Neumann, H. | 登録日 | 2019-06-08 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Evolved, Selective Erasers of Distinct Lysine Acylations. Angew.Chem.Int.Ed.Engl., 59, 2020
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4ZU3
| Halohydrin hydrogen-halide-lyases, HheB | 分子名称: | 3-hydroxypentanedinitrile, Halohydrin epoxidase B, MAGNESIUM ION, ... | 著者 | Watanabe, F, Yu, F, Ohtaki, A, Yamanaka, Y, Noguchi, K, Yohda, M, Odaka, M. | 登録日 | 2015-05-15 | 公開日 | 2015-11-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of halohydrin hydrogen-halide-lyases from Corynebacterium sp. N-1074 Proteins, 83, 2015
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1IVV
| Crystal structure of copper amine oxidase from Arthrobacter globiformis: Early intermediate in topaquinone biogenesis | 分子名称: | COPPER (II) ION, amine oxidase | 著者 | Kim, M, Okajima, T, Kishishita, S, Yoshimura, M, Kawamori, A, Tanizawa, K, Yamaguchi, H. | 登録日 | 2002-03-29 | 公開日 | 2002-08-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | X-ray snapshots of quinone cofactor biogenesis in bacterial copper amine oxidase. Nat.Struct.Biol., 9, 2002
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1WWQ
| Solution Structure of Mouse ER | 分子名称: | Enhancer of rudimentary homolog | 著者 | Li, H, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-01-12 | 公開日 | 2006-01-03 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the mouse enhancer of rudimentary protein reveals a novel fold J.Biomol.Nmr, 32, 2005
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6IPW
| Crystal structure of CqsB2 from Streptomyces exfoliatus in complex with the product, 1-(2-hydroxypropyl)-2-methyl-carbazole-3,4-dione | 分子名称: | 2-methyl-1-[(2R)-2-oxidanylpropyl]-9H-carbazole-3,4-dione, CqsB2 | 著者 | Tomita, T, Kobayashi, M, Nishiyama, M, Kuzuyama, T. | 登録日 | 2018-11-05 | 公開日 | 2019-10-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | An Unprecedented Cyclization Mechanism in the Biosynthesis of Carbazole Alkaloids in Streptomyces. Angew.Chem.Int.Ed.Engl., 58, 2019
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4ZW1
| Crystal structure of hBRD4 in complex with BL-BI06 reveals a novel synthesized inhibitor that induces Beclin1-independent/ATG5-dependent autophagic cell death in breast cancer | 分子名称: | 1,2-ETHANEDIOL, 2-(4-hydroxy-3,5-dimethylphenyl)-7-methyl-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one, Bromodomain-containing protein 4 | 著者 | Liu, B, Zhang, S, Guo, M, Tian, M. | 登録日 | 2015-05-19 | 公開日 | 2016-06-22 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of hBRD4 in complex with BL-BI06 reveals a novel synthesized inhibitor that induces Beclin1-independent/ATG5-dependent autophagic cell death in breast cancer To Be Published
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1IXN
| Enzyme-Substrate Complex of Pyridoxine 5'-Phosphate Synthase | 分子名称: | 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, Pyridoxine 5'-Phosphate Synthase, SN-GLYCEROL-3-PHOSPHATE | 著者 | Garrido-Franco, M, Laber, B, Huber, R, Clausen, T. | 登録日 | 2002-06-28 | 公開日 | 2003-02-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis J.MOL.BIOL., 321, 2002
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5LP6
| Crystal structure of Tubulin-Stathmin-TTL-Thiocolchicine Complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | 著者 | Marangon, J, Christodoulou, M, Casagrande, F, Tiana, G, Dalla Via, L, Aliverti, A, Passarella, D, Cappelletti, G, Ricagno, S. | 登録日 | 2016-08-11 | 公開日 | 2016-09-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Tools for the rational design of bivalent microtubule-targeting drugs. Biochem. Biophys. Res. Commun., 479, 2016
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5A7D
| Tetrameric assembly of LGN with Inscuteable | 分子名称: | INSCUTEABLE, PINS | 著者 | Culurgioni, S, Mari, S, Bonetto, G, Gallini, S, Brennich, M, Round, A, Mapelli, M. | 登録日 | 2015-07-07 | 公開日 | 2016-08-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | The Structure of the Insc:Lgn Tetramer Reveals a New Function of Lgn in Promoting Asymmetric Cell Divisions To be Published
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7PY4
| Cryo-EM structure of ATP8B1-CDC50A in E2P autoinhibited state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BERYLLIUM TRIFLUORIDE ION, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Dieudonne, T, Abad-Herrera, S, Juknaviciute Laursen, M, Lejeune, M, Stock, C, Slimani, K, Jaxel, C, Lyons, J.A, Montigny, C, Gunther Pomorski, T, Nissen, P, Lenoir, G. | 登録日 | 2021-10-08 | 公開日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Autoinhibition and regulation by phosphoinositides of ATP8B1, a human lipid flippase associated with intrahepatic cholestatic disorders. Elife, 11, 2022
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3LMM
| Crystal Structure of the DIP2311 protein from Corynebacterium diphtheriae, Northeast Structural Genomics Consortium Target CdR35 | 分子名称: | CHLORIDE ION, COBALT (II) ION, Uncharacterized protein | 著者 | Forouhar, F, Lew, S, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Buchwald, W.A, Maglaqui, M, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2010-01-31 | 公開日 | 2010-02-16 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target CdR35 To be Published
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2LY3
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1J2J
| Crystal structure of GGA1 GAT N-terminal region in complex with ARF1 GTP form | 分子名称: | ADP-ribosylation factor 1, ADP-ribosylation factor binding protein GGA1, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Shiba, T, Kawasaki, M, Takatsu, H, Nogi, T, Matsugaki, N, Igarashi, N, Suzuki, M, Kato, R, Nakayama, K, Wakatsuki, S. | 登録日 | 2003-01-05 | 公開日 | 2003-05-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport NAT.STRUCT.BIOL., 10, 2003
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1IQ8
| Crystal Structure of archaeosine tRNA-guanine transglycosylase from Pyrococcus horikoshii | 分子名称: | ARCHAEOSINE TRNA-GUANINE TRANSGLYCOSYLASE, MAGNESIUM ION, ZINC ION | 著者 | Ishitani, R, Nureki, O, Fukai, S, Kijimoto, T, Nameki, N, Watanabe, M, Kondo, H, Sekine, M, Okada, N, Nishimura, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2001-07-09 | 公開日 | 2002-05-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of archaeosine tRNA-guanine transglycosylase. J.Mol.Biol., 318, 2002
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1IQX
| CRYSTAL STRUCTURE OF COBALT-SUBSTITUTED AMINE OXIDASE FROM ARTHROBACTER GLOBIFORMIS | 分子名称: | CO(II)-SUBSTITUTED AMINE OXIDASE, COBALT (II) ION | 著者 | Kishishita, S, Okajima, T, Mure, M, Kim, M, Yamaguchi, H, Hirota, S, Suzuki, S, Kuroda, S, Tanizawa, K. | 登録日 | 2001-08-27 | 公開日 | 2003-02-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Role of Copper Ion in Bacterial Copper Amine Oxidase: Spectroscopic and Crystallographic Studies of Metal-Substituted Enzymes J.AM.CHEM.SOC., 125, 2003
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6IF6
| Structure of the periplasmic domain of SflA | 分子名称: | GLYCEROL, PHOSPHATE ION, Protein SflA | 著者 | Nishikawa, S, Sakuma, M, Kojima, S, Homma, M, Imada, K. | 登録日 | 2018-09-18 | 公開日 | 2019-05-01 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of the periplasmic domain of SflA involved in spatial regulation of the flagellar biogenesis of Vibrio reveals a TPR/SLR-like fold. J.Biochem., 166, 2019
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