2B98
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![BU of 2b98 by Molmil](/molmil-images/mine/2b98) | Crystal Structure of an archaeal pentameric riboflavin synthase | 分子名称: | Riboflavin synthase | 著者 | Ramsperger, A, Augustin, M, Schott, A.K, Gerhardt, S, Krojer, T, Eisenreich, W, Illarionov, B, Cushman, M, Bacher, A, Huber, R, Fischer, M. | 登録日 | 2005-10-11 | 公開日 | 2005-11-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of an Archaeal Pentameric Riboflavin Synthase in Complex with a Substrate Analog Inhibitor: stereochemical implications J.Biol.Chem., 281, 2006
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1JQL
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![BU of 1jql by Molmil](/molmil-images/mine/1jql) | Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of E. coli DNA Polymerase III: Structure of beta-delta (1-140) | 分子名称: | DNA Polymerase III, BETA CHAIN, DELTA SUBUNIT | 著者 | Jeruzalmi, D, Yurieva, O, Zhao, Y, Young, M, Stewart, J, Hingorani, M, O'Donnell, M, Kuriyan, J. | 登録日 | 2001-08-07 | 公開日 | 2001-09-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III. Cell(Cambridge,Mass.), 106, 2001
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6H5C
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![BU of 6h5c by Molmil](/molmil-images/mine/6h5c) | Crystal structure of DHQ1 from Salmonella typhi covalently modified by ligand 1 | 分子名称: | (1~{S},3~{R},4~{S},5~{R})-3-methyl-3,4,5-tris(hydroxyl)cyclohexane-1-carboxylic Acid, 3-dehydroquinate dehydratase | 著者 | Sanz-Gaitero, M, Maneiro, M, Lence, E, Otero, J.M, Thompson, P, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J. | 登録日 | 2018-07-24 | 公開日 | 2019-07-24 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | Hydroxylammonium Derivatives for Selective Active-site Lysine Modification in the Anti-virulence Bacterial Target DHQ1 Enzyme. Org Chem Front, 9, 2019
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3N99
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![BU of 3n99 by Molmil](/molmil-images/mine/3n99) | Crystal structure of TM1086 | 分子名称: | CHLORIDE ION, uncharacterized protein TM1086 | 著者 | Chruszcz, M, Domagalski, M.J, Wang, S, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2010-05-28 | 公開日 | 2010-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Crystal structure of TM1086 To be Published
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3NDS
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![BU of 3nds by Molmil](/molmil-images/mine/3nds) | Crystal structure of engineered Naja Nigricollis toxin alpha | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, SULFATE ION, Short neurotoxin 1 | 著者 | Stura, E.A, Drevet, P, Gregory, G, Gallopin, M, Vandame, M. | 登録日 | 2010-06-08 | 公開日 | 2010-08-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Conformational exchange is critical for the productivity of an oxidative folding intermediate with buried free cysteines. J.Mol.Biol., 403, 2010
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5WOP
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![BU of 5wop by Molmil](/molmil-images/mine/5wop) | High Resolution Structure of Mutant CA09-PB2cap | 分子名称: | GLYCEROL, Polymerase PB2 | 著者 | Constantinides, A.E, Gumpper, R.H, Severin, C, Luo, M. | 登録日 | 2017-08-02 | 公開日 | 2017-12-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | High-resolution structure of the Influenza A virus PB2cap binding domain illuminates the changes induced by ligand binding. Acta Crystallogr F Struct Biol Commun, 74, 2018
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3NGO
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![BU of 3ngo by Molmil](/molmil-images/mine/3ngo) | Crystal structure of the human CNOT6L nuclease domain in complex with poly(A) DNA | 分子名称: | 5'-D(*AP*AP*AP*A)-3', CCR4-NOT transcription complex subunit 6-like, MAGNESIUM ION | 著者 | Wang, H, Morita, M, Yang, W, Bartlam, M, Yamamoto, T, Rao, Z. | 登録日 | 2010-06-12 | 公開日 | 2010-07-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity. Embo J., 2010
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6H03
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![BU of 6h03 by Molmil](/molmil-images/mine/6h03) | OPEN CONFORMATION OF THE MEMBRANE ATTACK COMPLEX | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ... | 著者 | Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D. | 登録日 | 2018-07-06 | 公開日 | 2018-12-19 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers. Nat Commun, 9, 2018
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3N0S
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![BU of 3n0s by Molmil](/molmil-images/mine/3n0s) | Crystal structure of BA2930 mutant (H183A) in complex with AcCoA | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETYL COENZYME *A, Aminoglycoside N3-acetyltransferase, ... | 著者 | Klimecka, M.M, Chruszcz, M, Porebski, P.J, Cymborowski, M, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-05-14 | 公開日 | 2010-06-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural Analysis of a Putative Aminoglycoside N-Acetyltransferase from Bacillus anthracis. J.Mol.Biol., 410, 2011
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1ULQ
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![BU of 1ulq by Molmil](/molmil-images/mine/1ulq) | Crystal structure of tt0182 from Thermus thermophilus HB8 | 分子名称: | putative acetyl-CoA acetyltransferase | 著者 | Ago, H, Hamada, K, Ida, K, Kanda, H, Sugahara, M, Yamamoto, M, Kuroishi, C, Kuramitsu, S, Yokoyama, S, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2003-09-16 | 公開日 | 2004-11-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of tt0182 from Thermus thermophilus HB8 To be Published
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6CJ0
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6GZA
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![BU of 6gza by Molmil](/molmil-images/mine/6gza) | Structure of murine leukemia virus capsid C-terminal domain | 分子名称: | COBALT (II) ION, Capsid protein | 著者 | Qu, K, Dolezal, M, Schur, F.K.M, Murciano, B, Rumlova, M, Ruml, T, Briggs, J.A.G. | 登録日 | 2018-07-03 | 公開日 | 2018-12-05 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structure and architecture of immature and mature murine leukemia virus capsids. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3N23
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![BU of 3n23 by Molmil](/molmil-images/mine/3n23) | Crystal structure of the high affinity complex between ouabain and the E2P form of the sodium-potassium pump | 分子名称: | MAGNESIUM ION, Na+/K+ ATPase gamma subunit transcript variant a, OUABAIN, ... | 著者 | Yatime, L, Laursen, M, Morth, J.P, Esmann, M, Nissen, P, Fedosova, N.U. | 登録日 | 2010-05-17 | 公開日 | 2011-01-19 | 最終更新日 | 2014-09-17 | 実験手法 | X-RAY DIFFRACTION (4.6 Å) | 主引用文献 | Structural insights into the high affinity binding of cardiotonic steroids to the Na+,K+-ATPase. J.Struct.Biol., 174, 2011
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2BAG
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![BU of 2bag by Molmil](/molmil-images/mine/2bag) | 3D Structure of Torpedo californica acetylcholinesterase complexed with Ganstigmine | 分子名称: | 1S,3AS,8AS-TRIMETHYL-1-OXIDO-1,2,3,3A,8,8A-HEXAHYDROPYRROLO[2,3-B]INDOL-5-YL 2-ETHYLPHENYLCARBAMATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Lamba, D, Bartolucci, C, Siotto, M, Racchi, M, Villetti, G, Delcanale, M. | 登録日 | 2005-10-14 | 公開日 | 2006-08-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural Determinants of Torpedo californica Acetylcholinesterase Inhibition by the Novel and Orally Active Carbamate Based Anti-Alzheimer Drug Ganstigmine (CHF-2819) J.Med.Chem., 49, 2006
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5ZX1
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6H1F
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![BU of 6h1f by Molmil](/molmil-images/mine/6h1f) | Structure of the nanobody-stabilized gelsolin D187N variant (second domain) | 分子名称: | Gelsolin, THIOCYANATE ION, gelsolin nanobody, ... | 著者 | Hassan, A, Milani, M, Mastrangelo, E, de Rosa, M. | 登録日 | 2018-07-11 | 公開日 | 2019-01-23 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant. Biochim Biophys Acta Mol Basis Dis, 1865, 2019
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5TO3
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![BU of 5to3 by Molmil](/molmil-images/mine/5to3) | Crystal structure of thrombin mutant W215A/E217A fused to EGF456 of thrombomodulin via a 31-residue linker and bound to PPACK | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | 著者 | Barranco-Medina, S, Murphy, M, Pelc, L, Chen, Z, Di Cera, E, Pozzi, N. | 登録日 | 2016-10-16 | 公開日 | 2017-03-29 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Rational Design of Protein C Activators. Sci Rep, 7, 2017
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6H04
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![BU of 6h04 by Molmil](/molmil-images/mine/6h04) | Closed conformation of the Membrane Attack Complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ... | 著者 | Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D. | 登録日 | 2018-07-06 | 公開日 | 2018-12-19 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers. Nat Commun, 9, 2018
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1GEG
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![BU of 1geg by Molmil](/molmil-images/mine/1geg) | CRYATAL STRUCTURE ANALYSIS OF MESO-2,3-BUTANEDIOL DEHYDROGENASE | 分子名称: | ACETOIN REDUCTASE, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ... | 著者 | Otagiri, M, Kurisu, G, Ui, S, Kusunoki, M. | 登録日 | 2000-11-10 | 公開日 | 2001-02-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of meso-2,3-butanediol dehydrogenase in a complex with NAD+ and inhibitor mercaptoethanol at 1.7 A resolution for understanding of chiral substrate recognition mechanisms. J.Biochem., 129, 2001
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1G7E
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![BU of 1g7e by Molmil](/molmil-images/mine/1g7e) | NMR STRUCTURE OF N-DOMAIN OF ERP29 PROTEIN | 分子名称: | ENDOPLASMIC RETICULUM PROTEIN ERP29 | 著者 | Liepinsh, E, Mkrtchian, S, Barishev, M, Sharipo, M, Ingelman-Sundberg, M, Otting, G. | 登録日 | 2000-11-10 | 公開日 | 2000-11-29 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Thioredoxin fold as homodimerization module in the putative chaperone ERp29: NMR structures of the domains and experimental model of the 51 kDa dimer. Structure, 9, 2001
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5O9H
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![BU of 5o9h by Molmil](/molmil-images/mine/5o9h) | Crystal structure of thermostabilised human C5a anaphylatoxin chemotactic receptor 1 (C5aR) in complex with NDT9513727 | 分子名称: | 1-(1,3-benzodioxol-5-yl)-~{N}-(1,3-benzodioxol-5-ylmethyl)-~{N}-[(3-butyl-2,5-diphenyl-imidazol-4-yl)methyl]methanamine, C5a anaphylatoxin chemotactic receptor 1, CITRIC ACID, ... | 著者 | Robertson, N, Rappas, M, Dore, A.S, Brown, J, Bottegoni, G, Koglin, M, Cansfield, J, Jazayeri, A, Cooke, R.M, Marshall, F.H. | 登録日 | 2017-06-19 | 公開日 | 2018-01-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of the complement C5a receptor bound to the extra-helical antagonist NDT9513727. Nature, 553, 2018
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6H5J
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![BU of 6h5j by Molmil](/molmil-images/mine/6h5j) | Crystal structure of DHQ1 from Salmonella typhi covalently modified by ligand 4 | 分子名称: | (3~{R})-3,4,5-tris(hydroxyl)cyclohexane-1-carboxylic acid, 3-dehydroquinate dehydratase | 著者 | Otero, J.M, Maneiro, M, Lence, E, Sanz-Gaitero, M, Thompson, P, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J. | 登録日 | 2018-07-24 | 公開日 | 2019-07-24 | 最終更新日 | 2019-10-09 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Hydroxylammonium Derivatives for Selective Active-site Lysine Modification in the Anti-virulence Bacterial Target DHQ1 Enzyme. Org Chem Front, 6, 2019
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1V25
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![BU of 1v25 by Molmil](/molmil-images/mine/1v25) | Crystal structure of tt0168 from Thermus thermophilus HB8 | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, long-chain-fatty-acid-CoA synthetase | 著者 | Hisanaga, Y, Ago, H, Nakatsu, T, Hamada, K, Ida, K, Kanda, H, Yamamoto, M, Hori, T, Arii, Y, Sugahara, M, Kuramitsu, S, Yokoyama, S, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2003-10-07 | 公開日 | 2004-07-27 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis of the Substrate-specific Two-step Catalysis of Long Chain Fatty Acyl-CoA Synthetase Dimer J.Biol.Chem., 279, 2004
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1GBR
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![BU of 1gbr by Molmil](/molmil-images/mine/1gbr) | ORIENTATION OF PEPTIDE FRAGMENTS FROM SOS PROTEINS BOUND TO THE N-TERMINAL SH3 DOMAIN OF GRB2 DETERMINED BY NMR SPECTROSCOPY | 分子名称: | GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, SOS-A PEPTIDE | 著者 | Wittekind, M, Mapelli, C, Farmer, B.T, Suen, K.-L, Goldfarb, V, Tsao, J, Lavoie, T, Barbacid, M, Meyers, C.A, Mueller, L. | 登録日 | 1994-08-12 | 公開日 | 1995-01-26 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Orientation of peptide fragments from Sos proteins bound to the N-terminal SH3 domain of Grb2 determined by NMR spectroscopy. Biochemistry, 33, 1994
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1V3U
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![BU of 1v3u by Molmil](/molmil-images/mine/1v3u) | Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase in apo form | 分子名称: | CHLORIDE ION, leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase | 著者 | Hori, T, Yokomizo, T, Ago, H, Sugahara, M, Ueno, G, Yamamoto, M, Kumasaka, T, Shimizu, T, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2003-11-05 | 公開日 | 2004-07-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of leukotriene B4 12-hydroxydehydrogenase/15-Oxo-prostaglandin 13-reductase catalytic mechanism and a possible Src homology 3 domain binding loop J.Biol.Chem., 279, 2004
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