1V3U

Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase in apo form

Summary for 1V3U

Related1V3T 1V3V
Descriptorleukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase, CHLORIDE ION (3 entities in total)
Functional Keywordsrossmann fold, riken structural genomics/proteomics initiative, rsgi, structural genomics, oxidoreductase
Biological sourceCavia porcellus (domestic guinea pig)
Cellular locationCytoplasm (By similarity) Q9EQZ5
Total number of polymer chains2
Total molecular weight72712.12
Authors
Hori, T.,Yokomizo, T.,Ago, H.,Sugahara, M.,Ueno, G.,Yamamoto, M.,Kumasaka, T.,Shimizu, T.,Miyano, M.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2003-11-05, release date: 2004-07-13, Last modification date: 2011-07-13)
Primary citation
Hori, T.,Yokomizo, T.,Ago, H.,Sugahara, M.,Ueno, G.,Yamamoto, M.,Kumasaka, T.,Shimizu, T.,Miyano, M.
Structural basis of leukotriene B4 12-hydroxydehydrogenase/15-Oxo-prostaglandin 13-reductase catalytic mechanism and a possible Src homology 3 domain binding loop
J.Biol.Chem., 279:22615-22623, 2004
PubMed: 15007077 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M312655200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.214701.2%5.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report