6H5J
Crystal structure of DHQ1 from Salmonella typhi covalently modified by ligand 4
Summary for 6H5J
Entry DOI | 10.2210/pdb6h5j/pdb |
Descriptor | 3-dehydroquinate dehydratase, (3~{R})-3,4,5-tris(hydroxyl)cyclohexane-1-carboxylic acid (3 entities in total) |
Functional Keywords | lyase activity, chorismate biosynthetic process, 3-dehydroquinase, covalent inhibitor, lyase |
Biological source | Salmonella typhi |
Total number of polymer chains | 1 |
Total formula weight | 27857.16 |
Authors | Otero, J.M.,Maneiro, M.,Lence, E.,Sanz-Gaitero, M.,Thompson, P.,Hawkins, A.R.,Gonzalez-Bello, C.,van Raaij, M.J. (deposition date: 2018-07-24, release date: 2019-07-24, Last modification date: 2019-10-09) |
Primary citation | Maneiro, M.,Lence, E.,Sanz-Gaitero, M.,Otero, J.M.,van Raaij, M.J.,Thompson, P.,Hawkins, A.R.,Gonzalez-Bello, C. Hydroxylammonium Derivatives for Selective Active-site Lysine Modification in the Anti-virulence Bacterial Target DHQ1 Enzyme. Org Chem Front, 6:3127-3135, 2019 Cited by DOI: 10.1039/c9qo00453jPDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
Download full validation report