1WIJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wij by Molmil](/molmil-images/mine/1wij) | Solution Structure of the DNA-Binding Domain of Ethylene-Insensitive3-Like3 | 分子名称: | ETHYLENE-INSENSITIVE3-like 3 protein | 著者 | Yamasaki, K, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2004-05-28 | 公開日 | 2004-11-28 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the major DNA-binding domain of Arabidopsis thaliana ethylene-insensitive3-like3. J.Mol.Biol., 348, 2005
|
|
8J0N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j0n by Molmil](/molmil-images/mine/8j0n) | cryo-EM structure of human EMC | 分子名称: | ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ER membrane protein complex subunit 2, ... | 著者 | Li, M, Zhang, C, Wu, J, Lei, M. | 登録日 | 2023-04-11 | 公開日 | 2024-04-03 | 最終更新日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Structural insights into human EMC and its interaction with VDAC. Aging (Albany NY), 16, 2024
|
|
6CXZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6cxz by Molmil](/molmil-images/mine/6cxz) | RNA octamer containing 2'-F, 4'-Calpha-Me U. | 分子名称: | CACODYLATE ION, COBALT HEXAMMINE(III), RNA (5'-R(*CP*GP*AP*AP*(U4M)P*UP*CP*G)-3') | 著者 | Harp, J.M, Egli, M. | 登録日 | 2018-04-04 | 公開日 | 2018-08-29 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural basis for the synergy of 4'- and 2'-modifications on siRNA nuclease resistance, thermal stability and RNAi activity. Nucleic Acids Res., 46, 2018
|
|
1WMG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wmg by Molmil](/molmil-images/mine/1wmg) | Crystal structure of the UNC5H2 death domain | 分子名称: | SULFATE ION, SULFITE ION, netrin receptor Unc5h2 | 著者 | Handa, N, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2004-07-09 | 公開日 | 2005-01-09 | 最終更新日 | 2011-11-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of the UNC5H2 death domain ACTA CRYSTALLOGR.,SECT.D, 62, 2006
|
|
8J4C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j4c by Molmil](/molmil-images/mine/8j4c) | YeeE(TsuA)-YeeD(TsuB) complex for thiosulfate uptake | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Spirochaeta thermophila YeeE(TsuA)-YeeD(TsuB),UPF0033 domain-containing protein, SirA-like domain-containing protein (chimera), ... | 著者 | Ikei, M, Miyazaki, R, Monden, K, Naito, Y, Takeuchi, A, Takahashi, Y.S, Tanaka, Y, Ichikawa, M, Tsukazaki, T. | 登録日 | 2023-04-19 | 公開日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.34 Å) | 主引用文献 | Structure and function of YeeE-YeeD complex for sophisticated thiosulfate uptake To Be Published
|
|
5UQH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uqh by Molmil](/molmil-images/mine/5uqh) | Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor p182 | 分子名称: | 1,2-ETHANEDIOL, INOSINIC ACID, ISOPROPYL ALCOHOL, ... | 著者 | Kim, Y, Maltseva, N, Makowska-Grzyska, M, Gu, M, Gollapalli, D, Hedstrom, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2017-02-08 | 公開日 | 2017-03-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the presence of TBK6 To Be Published
|
|
6JPP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jpp by Molmil](/molmil-images/mine/6jpp) | |
6T36
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6t36 by Molmil](/molmil-images/mine/6t36) | Crystal structure of the PTPN3 PDZ domain bound to the HBV core protein C-terminal peptide | 分子名称: | BROMIDE ION, Capsid protein, Tyrosine-protein phosphatase non-receptor type 3 | 著者 | Genera, M, Mechaly, A, Haouz, A, Caillet-Saguy, C. | 登録日 | 2019-10-10 | 公開日 | 2021-01-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein. Sci Rep, 11, 2021
|
|
7KEO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7keo by Molmil](/molmil-images/mine/7keo) | Crystal structure of K29-linked di-ubiquitin in complex with synthetic antigen binding fragment | 分子名称: | PHOSPHATE ION, Synthetic antigen binding fragment, heavy chain, ... | 著者 | Yu, Y, Zheng, Q, Erramilli, S, Pan, M, Kossiakoff, A, Liu, L, Zhao, M. | 登録日 | 2020-10-11 | 公開日 | 2021-07-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle. Nat.Chem.Biol., 17, 2021
|
|
6T6I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6t6i by Molmil](/molmil-images/mine/6t6i) | |
6F5M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6f5m by Molmil](/molmil-images/mine/6f5m) | Crystal structure of highly glycosylated human leukocyte elastase in complex with a thiazolidinedione inhibitor | 分子名称: | 5-[[4-[[(2~{S})-4-methyl-1-oxidanylidene-1-[(2-propylphenyl)amino]pentan-2-yl]carbamoyl]phenyl]methyl]-2-oxidanylidene-1,3-thiazol-1-ium-4-olate, ACETATE ION, Neutrophil elastase, ... | 著者 | Hochscherf, J, Pietsch, M, Tieu, W, Kuan, K, Hautmann, S, Abell, A, Guetschow, M, Niefind, K. | 登録日 | 2017-12-01 | 公開日 | 2018-08-08 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of highly glycosylated human leukocyte elastase in complex with an S2' site binding inhibitor. Acta Crystallogr F Struct Biol Commun, 74, 2018
|
|
6CCL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ccl by Molmil](/molmil-images/mine/6ccl) | Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with 1-benzyl-1H-imidazo[4,5-b]pyridine | 分子名称: | 1-benzyl-1H-imidazo[4,5-b]pyridine, DIMETHYL SULFOXIDE, Phosphopantetheine adenylyltransferase, ... | 著者 | Mamo, M, Appleton, B.A. | 登録日 | 2018-02-07 | 公開日 | 2018-03-14 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Fragment-Based Drug Discovery of Inhibitors of Phosphopantetheine Adenylyltransferase from Gram-Negative Bacteria. J. Med. Chem., 61, 2018
|
|
8JER
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jer by Molmil](/molmil-images/mine/8jer) | Structure of Acipimox-GPR109A-G protein complex | 分子名称: | 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Yadav, M.K, Sarma, P, Chami, M, Banerjee, R, Shukla, A.K. | 登録日 | 2023-05-16 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Structure-guided engineering of biased-agonism in the human niacin receptor via single amino acid substitution. Nat Commun, 15, 2024
|
|
5GSA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gsa by Molmil](/molmil-images/mine/5gsa) | EED in complex with an allosteric PRC2 inhibitor | 分子名称: | Histone-lysine N-methyltransferase EZH2, N-(furan-2-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, Polycomb protein EED | 著者 | Zhao, K, Zhao, M, Luo, X, Zhang, H. | 登録日 | 2016-08-15 | 公開日 | 2017-02-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of Nat. Chem. Biol., 13, 2017
|
|
6CDT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6cdt by Molmil](/molmil-images/mine/6cdt) | |
8J0O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j0o by Molmil](/molmil-images/mine/8j0o) | cryo-EM structure of human EMC and VDAC | 分子名称: | ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ER membrane protein complex subunit 2, ... | 著者 | Li, M, Zhang, C, Wu, J, Lei, M. | 登録日 | 2023-04-11 | 公開日 | 2024-04-03 | 最終更新日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | Structural insights into human EMC and its interaction with VDAC. Aging (Albany NY), 16, 2024
|
|
2QZ4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qz4 by Molmil](/molmil-images/mine/2qz4) | Human paraplegin, AAA domain in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Paraplegin | 著者 | Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Herman, M.D, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, J, Sagemark, C, Sundstrom, M, Thorsell, A.G, Tresauges, L, Van Den Berg, S, Weigelt, J, Welin, M, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC) | 登録日 | 2007-08-16 | 公開日 | 2007-09-11 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Crystal Structure of the ATPase Domain of the Human AAA+ Protein Paraplegin/SPG7. Plos One, 4, 2009
|
|
6CRF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6crf by Molmil](/molmil-images/mine/6crf) | |
5UK3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uk3 by Molmil](/molmil-images/mine/5uk3) | |
5URQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5urq by Molmil](/molmil-images/mine/5urq) | Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor p176 | 分子名称: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase, N-{2-chloro-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]phenyl}-alpha-D-ribofuranosylamine, ... | 著者 | Kim, Y, Maltseva, N, Makowska-Grzyska, M, Gu, M, Gollapalli, D, Hedstrom, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2017-02-12 | 公開日 | 2017-03-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor p176 To Be Published
|
|
2QG5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qg5 by Molmil](/molmil-images/mine/2qg5) | Cryptosporidium parvum calcium dependent protein kinase cgd7_1840 | 分子名称: | Calcium/calmodulin-dependent protein kinase | 著者 | Lunin, V.V, Wernimont, A.K, Lew, J, Wasney, G, Kozieradzki, I, Vedadi, M, Bochkarev, A, Arrowsmith, C.H, Sundstrom, M, Weigelt, J, Edwards, A.E, Hui, R, Artz, J, Amani, M, Structural Genomics Consortium (SGC) | 登録日 | 2007-06-28 | 公開日 | 2007-09-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Cryptosporidium parvum calcium dependent protein kinase cgd7_1840 To be Published
|
|
5NCR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ncr by Molmil](/molmil-images/mine/5ncr) | OH1 from the Orf virus: a tyrosine phosphatase that displays distinct structural features and triple substrate specificity | 分子名称: | PHOSPHATE ION, SULFATE ION, tyrosine phosphatase | 著者 | Segovia, D, Haouz, A, Berois, M, Villarino, A, Andre-Leroux, G. | 登録日 | 2017-03-06 | 公開日 | 2017-08-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | OH1 from Orf Virus: A New Tyrosine Phosphatase that Displays Distinct Structural Features and Triple Substrate Specificity. J. Mol. Biol., 429, 2017
|
|
3LLM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3llm by Molmil](/molmil-images/mine/3llm) | Crystal Structure Analysis of a RNA Helicase | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase A, CACODYLATE ION, ... | 著者 | Schutz, P, Karlberg, T, Collins, R, Arrowsmith, C.H, Berglund, H, Bountra, C, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kraulis, P, Kotenyova, T, Kotzsch, A, Markova, N, Moche, M, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H.M, Structural Genomics Consortium (SGC) | 登録日 | 2010-01-29 | 公開日 | 2010-05-12 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein. J.Mol.Biol., 400, 2010
|
|
5UQF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uqf by Molmil](/molmil-images/mine/5uqf) | Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with IMP and the inhibitor P225 | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Kim, Y, Maltseva, N, Makowska-Grzyska, M, Gu, M, Gollapalli, D, Hedstrom, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2017-02-08 | 公開日 | 2017-03-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from
Campylobacter jejuni in the complex with IMP and the inhibitor P225 To Be Published
|
|
8JFV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jfv by Molmil](/molmil-images/mine/8jfv) | Crystal structure of Catabolite repressor acivator from E. coli in complex with sulisobenzone | 分子名称: | 1,2-ETHANEDIOL, 2-methoxy-4-oxidanyl-5-(phenylcarbonyl)benzenesulfonic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Neetu, N, Sharma, M, Mahto, J.K, Kumar, P. | 登録日 | 2023-05-19 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Sulisobenzone is a potent inhibitor of the global transcription factor Cra. J.Struct.Biol., 215, 2023
|
|