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PDB: 52230 件

7Y0I
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Solution structures of ASH1L PHD domain in complex with H3K4me2 peptide
分子名称: ALA-ARG-THR-MLY-GLN-THR-ALA-ARG-LYS-SER-THR-GLY-GLY-LYS-ALA, Histone-lysine N-methyltransferase ASH1L, ZINC ION
著者Yu, M, Zeng, L.
登録日2022-06-05
公開日2022-10-12
実験手法SOLUTION NMR
主引用文献Structural insight into ASH1L PHD finger recognizing methylated histone H3K4 and promoting cell growth in prostate cancer.
Front Oncol, 12, 2022
7KKF
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Crystal Structure of S. cerevisiae Ess1
分子名称: Peptidyl-prolyl cis-trans isomerase ESS1
著者Namitz, K.E.W, Alicea-Velazquez, N.L, Cosgrove, M.S, Hanes, S.D.
登録日2020-10-27
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure analysis suggests Ess1 isomerizes the carboxy-terminal domain of RNA polymerase II via a bivalent anchoring mechanism.
Commun Biol, 4, 2021
7XZX
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Cryo-EM structure of the nucleosome in complex with p53 DNA-binding domain
分子名称: Cellular tumor antigen p53, DNA (193-MER), Histone H2A type 1-B/E, ...
著者Nishimura, M, Nozawa, K, Takizawa, Y, Kurumizaka, H.
登録日2022-06-03
公開日2022-10-12
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.53 Å)
主引用文献Structural basis for p53 binding to its nucleosomal target DNA sequence.
Pnas Nexus, 1, 2022
3B9B
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Structure of the E2 beryllium fluoride complex of the SERCA Ca2+-ATPase
分子名称: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, SODIUM ION, ...
著者Olesen, C, Picard, M, Winther, A.M.L, Morth, J.P, Moller, J.V, Nissen, P.
登録日2007-11-04
公開日2007-12-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献The structural basis of calcium transport by the calcium pump.
Nature, 450, 2007
7XT3
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Crystal Structure of Hepatitis virus A 2C protein 128-335 aa
分子名称: Genome polyprotein, PHOSPHATE ION
著者Chen, P, Wojdyla, J.A, Li, Z, Wang, M, Cui, S.
登録日2022-05-16
公開日2022-07-27
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Biochemical and structural characterization of hepatitis A virus 2C reveals an unusual ribonuclease activity on single-stranded RNA.
Nucleic Acids Res., 50, 2022
7F26
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Crystal structure of lysozyme
分子名称: Lysozyme C
著者Liang, M.
登録日2021-06-10
公開日2021-09-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Novel combined crystallization plate for high-throughput crystal screening and in situ data collection at a crystallography beamline.
Acta Crystallogr.,Sect.F, 77, 2021
3BDN
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Crystal Structure of the Lambda Repressor
分子名称: DNA (5'-D(*DAP*DAP*DTP*DAP*DCP*DCP*DAP*DCP*DTP*DGP*DGP*DCP*DGP*DGP*DTP*DGP*DAP*DTP*DAP*DT)-3'), DNA (5'-D(*DTP*DAP*DTP*DAP*DTP*DCP*DAP*DCP*DCP*DGP*DCP*DCP*DAP*DGP*DTP*DGP*DGP*DTP*DAP*DT)-3'), Lambda Repressor
著者Stayrook, S.E, Jaru-Ampornpan, P, Hochschild, A, Lewis, M.
登録日2007-11-15
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.909 Å)
主引用文献Crystal structure of the lambda repressor and a model for pairwise cooperative operator binding
Nature, 452, 2008
3BF0
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Crystal structure of Escherichia coli Signal peptide peptidase (SppA), Native crystals
分子名称: Protease 4
著者Paetzel, M.
登録日2007-11-20
公開日2007-12-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of a bacterial signal Peptide peptidase.
J.Mol.Biol., 376, 2008
7EQ9
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Cryo-EM structure of designed protein nanoparticle TIP60 (Truncated Icosahedral Protein composed of 60-mer fusion proteins)
分子名称: TIP60
著者Obata, J, Kawakami, N, Tsutsumi, A, Miyamoto, K, Kikkawa, M, Arai, R.
登録日2021-04-30
公開日2021-09-15
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Icosahedral 60-meric porous structure of designed supramolecular protein nanoparticle TIP60.
Chem.Commun.(Camb.), 57, 2021
3BFO
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Crystal structure of Ig-like C2-type 2 domain of the human Mucosa-associated lymphoid tissue lymphoma translocation protein 1
分子名称: Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Isoform 2)
著者Walker, J.R, Akutsu, M, Littler, D.R, Li, Y, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-11-22
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structure of the Ig-like C2-type 2 domain of the human Mucosa-associated lymphoid tissue lymphoma translocation protein 1.
To be Published
7Y4K
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Crystal structure of Ricin A chain bound with N2-(2-amino-4-oxo-3,4-dihydropteridine-7-carbonyl)glycyl-L-phenylalanyl-N6-((benzyloxy)carbonyl)-L-ornitine
分子名称: (2S)-2-[[(2S)-2-[2-[(2-azanyl-4-oxidanylidene-3H-pteridin-7-yl)carbonylamino]ethanoylamino]-3-phenyl-propanoyl]amino]-5-(phenylmethoxycarbonylamino)pentanoic acid, Ricin A chain, SULFATE ION
著者Katakura, S, Goto, M, Ohba, T, Kawata, R, Nagatsu, K, Higashi, S, Matsumoto, K, Kurisu, K, Ohtsuka, K, Saito, R.
登録日2022-06-15
公開日2022-11-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Pterin-based small molecule inhibitor capable of binding to the secondary pocket in the active site of ricin-toxin A chain.
Plos One, 17, 2022
3B08
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Crystal structure of the mouse HOIL1-L-NZF in complex with linear di-ubiquitin
分子名称: Polyubiquitin-C, RanBP-type and C3HC4-type zinc finger-containing protein 1, ZINC ION, ...
著者Sato, Y, Fujita, H, Yoshikawa, A, Yamashita, M, Yamagata, A, Kaiser, S.E, Iwai, K, Fukai, S.
登録日2011-06-07
公開日2011-12-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex
Proc.Natl.Acad.Sci.USA, 108, 2011
3BIS
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BU of 3bis by Molmil
Crystal Structure of the PD-L1
分子名称: Programmed cell death 1 ligand 1
著者Lin, D.Y, Tanaka, Y, Iwasaki, M, Gittis, A.G, Su, H.P, Mikami, B, Okazaki, T, Honjo, T, Minato, N, Garboczi, D.N.
登録日2007-11-30
公開日2008-02-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors.
Proc.Natl.Acad.Sci.Usa, 105, 2008
6IN5
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Crystal structure of H5N2 hemagglutinin G228S Q226L mutant with 3SLN from A/chicken/Taiwan/0502/2012
分子名称: Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose
著者Lin, T.H, Lee, M.S, Liu, J.S.
登録日2018-10-24
公開日2019-10-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.916 Å)
主引用文献crystal structure of H5 hemagglutinin from A/chicken/Taiwan/0502/2012
To Be Published
3EL0
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Crystal structure of the inhibitor Nelfinavir (NFV) in complex with a multi-drug resistant HIV-1 protease variant (L10I/G48V/I54V/V64I/V82A) (Refer: FLAP+ in citation)
分子名称: 2-[2-HYDROXY-3-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-4-PHENYL SULFANYL-BUTYL]-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID TERT-BUTYLAMIDE, ACETATE ION, PHOSPHATE ION, ...
著者Prabu-Jeyabalan, M, King, N.M.
登録日2008-09-19
公開日2009-09-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Extreme Entropy-Enthalpy Compensation in a Drug-Resistant Variant of HIV-1 Protease.
Acs Chem.Biol., 7, 2012
3EOX
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BU of 3eox by Molmil
High quality structure of cleaved PAI-1-stab
分子名称: Plasminogen activator inhibitor 1
著者Dewilde, M, Declerck, P.J, Rabijns, A, Strelkov, S.V.
登録日2008-09-29
公開日2009-02-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献High quality structure of cleaved PAI-1-stab.
J.Struct.Biol., 165, 2009
7F8Y
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Crystal structure of the cholecystokinin receptor CCKAR in complex with devazepide
分子名称: N-[(3S)-1-methyl-2-oxidanylidene-5-phenyl-3H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide, fusion protein of Cholecystokinin receptor type A and Endolysin
著者Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q.
登録日2021-07-02
公開日2021-10-13
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of the human cholecystokinin receptors bound to agonists and antagonists.
Nat.Chem.Biol., 17, 2021
3EPM
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Crystal structure of Caulobacter crescentus ThiC
分子名称: 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, SULFATE ION, Thiamine biosynthesis protein thiC, ...
著者Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E.
登録日2008-09-29
公開日2008-10-28
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.793 Å)
主引用文献Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
6IM0
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Crystal structure of a highly thermostable carbonic anhydrase from Persephonella marina EX-H1
分子名称: BICARBONATE ION, CALCIUM ION, Carbonic anhydrase (Carbonate dehydratase), ...
著者Jin, M.S, Kim, S, Sung, J, Yeon, J, Choi, S.H.
登録日2018-10-21
公開日2019-07-17
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of a Highly Thermostable alpha-Carbonic Anhydrase from Persephonella marina EX-H1.
Mol.Cells, 42, 2019
7F8U
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Crystal structure of the cholecystokinin receptor CCKAR in complex with lintitript
分子名称: 2-[2-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]carbamoyl]indol-1-yl]ethanoic acid, Fusion protein of Cholecystokinin receptor type A and Endolysin
著者Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q.
登録日2021-07-02
公開日2021-10-13
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of the human cholecystokinin receptors bound to agonists and antagonists.
Nat.Chem.Biol., 17, 2021
7F8W
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Cryo-EM structure of the cholecystokinin receptor CCKBR in complex with gastrin-17 and Gq
分子名称: Gastrin-17, Gastrin/cholecystokinin type B receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q.
登録日2021-07-02
公開日2021-10-13
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structures of the human cholecystokinin receptors bound to agonists and antagonists.
Nat.Chem.Biol., 17, 2021
3EOE
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Crystal Structure of Pyruvate Kinase from toxoplasma gondii, 55.m00007
分子名称: GLYCEROL, Pyruvate kinase
著者Wernimont, A.K, Lew, J, Kozieradzki, I, Wasney, G, Hassani, A, Vedadi, M, Cossar, D, Schapiro, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Pizarro, J, Structural Genomics Consortium (SGC)
登録日2008-09-26
公開日2008-10-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The crystal structure of Toxoplasma gondii pyruvate kinase 1.
Plos One, 5, 2010
7F8V
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Cryo-EM structure of the cholecystokinin receptor CCKBR in complex with gastrin-17 and Gi
分子名称: Gastrin-17, Gastrin/cholecystokinin type B receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q.
登録日2021-07-02
公開日2021-10-13
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structures of the human cholecystokinin receptors bound to agonists and antagonists.
Nat.Chem.Biol., 17, 2021
3EC5
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The crystal structure of Thioflavin-T (ThT) binding OspA mutant
分子名称: Outer Surface Protein A, TETRAETHYLENE GLYCOL
著者Biancalana, M, Makabe, K, Koide, A, Koide, S.
登録日2008-08-28
公開日2009-02-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Molecular mechanism of thioflavin-T binding to the surface of beta-rich peptide self-assemblies
J.Mol.Biol., 385, 2009
7Y4M
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Crystal structure of Ricin A chain bound with N2-(2-amino-4-oxo-3,4-dihydropteridine-7-carbonyl)glycyl-L-phenylalanyl-N6-((benzyloxy)carbonyl)-L-lysine
分子名称: (2S)-2-[[(2S)-2-[2-[(2-azanyl-4-oxidanylidene-3H-pteridin-7-yl)carbonylamino]ethanoylamino]-3-phenyl-propanoyl]amino]-6-(phenylmethoxycarbonylamino)hexanoic acid, Ricin A chain, SULFATE ION
著者Katakura, S, Goto, M, Ohba, T, Kawata, R, Nagatsu, K, Higashi, S, Matsumoto, K, Kurisu, K, Ohtsuka, K, Saito, R.
登録日2022-06-15
公開日2022-11-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Pterin-based small molecule inhibitor capable of binding to the secondary pocket in the active site of ricin-toxin A chain.
Plos One, 17, 2022

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